Author

Leandro Silva da Costa

Observed names: LEANDRO SILVA DA COSTA, Leandro S. da Costa, Leandro Silva Da Costa

Observed institutions: Universidade Federal do Rio de Janeiro, Inserm, Aarhus University, Université Paris-Saclay, La Ligue Contre le Cancer, Hôpital Paul-Brousse

ORCID: 0000-0001-9697-4894

Observed ORCID: 0000-0001-9697-4894

OpenAlex ID: A5044286490

The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling

2019 · Mena Abdel-Nour, Leticia A. M. Carneiro, et al. · Science · 125

RNA viruses promote activation of the NLRP3 inflammasome through cytopathogenic effect-induced potassium efflux

2019 · Leandro Silva da Costa, Ahmed Outlioua, et al. · Cell Death and Disease · 118

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Mitochondrial and bioenergetic dysfunction in human hepatic cells infected with dengue 2 virus

2007 · Tatiana El-Bacha, Victor Midlej, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 110

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The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing

2016 · Marie Pourcelot, Naima Zemirli, et al. · BMC Biology · 78

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Infection of Endothelial Cells by Dengue Virus Induces ROS Production by Different Sources Affecting Virus Replication, Cellular Activation, Death and Vascular Permeability

2022 · Lana Monteiro Meuren, Elisa Beatriz Prestes, et al. · Frontiers in Immunology · 68

Macrophages as target cells for Mayaro virus infection: involvement of reactive oxygen species in the inflammatory response during virus replication

2016 · MARIANA G. CAVALHEIRO, LEANDRO SILVA DA COSTA, et al. · Anais da Academia Brasileira de Ciências · 51

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Anthocyanin-Rich Grape Pomace Extract (Vitis vinifera L.) from Wine Industry Affects Mitochondrial Bioenergetics and Glucose Metabolism in Human Hepatocarcinoma HepG2 Cells

2018 · Nathalia De Sales, Leandro Silva da Costa, et al. · Molecules · 46

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Mitochondrial Bioenergetic Alterations in Mouse Neuroblastoma Cells Infected with Sindbis Virus: Implications to Viral Replication and Neuronal Death

2012 · Leandro Silva da Costa, Ana Paula Pereira da Silva, et al. · PLoS ONE · 46

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DH82 Canine and RAW264.7 Murine Macrophage Cell Lines Display Distinct Activation Profiles Upon Interaction With Leishmania infantum and Leishmania amazonensis

2020 · Natalia Rocha Nadaes, Leandro Silva da Costa, et al. · Frontiers in Cellular and Infection Microbiology · 18

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Fragment‐Based Drug Discovery of Novel High‐affinity, Selective, and Anti‐inflammatory Inhibitors of the Keap1‐Nrf2 Protein‐Protein Interaction

2025 · Chunyu Lin, Dilip Narayanan, et al. · Angewandte Chemie International Edition · 10

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Large-scale deep learning identifies the antiviral potential of PKI-179 and MTI-31 against coronaviruses

2024 · Demi van der Horst, Madalina E. Carter-Timofte, et al. · Antiviral Research · 8

SAM68 directs STING signaling to apoptosis in macrophages

2024 · Demi van der Horst, Naziia Kurmasheva, et al. · Communications Biology · 8

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NRF2 activators and the inhibitor of nuclear export, selinexor, restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1 through an NRF2-independent mechanism

2026 · Fakhar H. Waqas, Leandro Silva da Costa, et al. · Communications Biology · 4

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Organelle Separation and Cell Signaling

2017 · Leandro Silva Da Costa, Damien Arnoult · Methods in molecular biology · 3

A TAK1-Driven NLRP1 Inflammasome Pathway Revealed by Phosphatase-Targeting Environmental Toxins

2026 · Margaux Paradis, Léana Gorse, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1

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Fragment‐Based Drug Discovery of Novel High‐affinity, Selective, and Anti‐inflammatory Inhibitors of the Keap1‐Nrf2 Protein‐Protein Interaction

2025 · Chunyu Lin, Dilip Narayanan, et al. · Angewandte Chemie

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S12.16 mitochondrial dysfunction in neuroblastoma cells infected with sindbis virus

2008 · Leandro S. da Costa, Antonio Galina, et al. · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Works count: 17

Citation count: 694

H-index: 10

I10-index: 10