Author

William Billard

Observed names: W Billard, W. Billard

OpenAlex ID: A5044379726

Characterization of the binding of 3H-SCH 23390, a selective D-1 receptor antagonist ligand, in rat striatum

1984 · William Billard, Vilma Ruperto, et al. · Life Sciences · 567

Identification of the primary muscarinic autoreceptor subtype in rat striatum as m2 through a correlation of in vivo microdialysis and in vitro receptor binding data.

1995 · W Billard, H Binch, et al. · Journal of Pharmacology and Experimental Therapeutics · 103

Design and synthesis of piperidinyl piperidine analogues as potent and selective M2 muscarinic receptor antagonists

2000 · Yuguang Wang, Samuel Chackalamannil, et al. · Bioorganic & Medicinal Chemistry Letters · 96

Pharmacology of SCH 34826, an orally active enkephalinase inhibitor analgesic.

1988 · R E Chipkin, J G Berger, et al. · Journal of Pharmacology and Experimental Therapeutics · 93

SCH 57790, a selective muscarinic M2 receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals

2001 · Galen J. Carey, William Billard, et al. · European Journal of Pharmacology · 74

Muscarinic agonists and antagonists in the treatment of Alzheimer's disease

2001 · W Greenlee, J Clader, et al. · Il Farmaco · 73

Facilitation of acetylcholine release and improvement in cognition by a selective M2 muscarinic antagonist, SCH 72788

2001 · Jean E. Lachowicz, Ruth A. Duffy, et al. · Life Sciences · 38

Relative activities of SCH 23390 and its analogs in three tests for D1/DA1 dopamine receptor antagonism

1986 · Allen Barnett, Ho-sam Ahn, et al. · European Journal of Pharmacology · 38

Selective affinity of 1-N-trifluoroethyl benzoidiazepines for cerebellar type 1 receptor sites

1984 · L.C. Iorio, A. Barnett, et al. · Life Sciences · 37

Benzazepines: Structure-Activity Relationships Between D1 Receptor Blockade and Selected Pharmacological Effects

1986 · Louis C. Iorio, Allen Barnett, et al. · Advances in experimental medicine and biology · 31

Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity

2003 · John W Clader, William Billard, et al. · Bioorganic & Medicinal Chemistry · 27

Selective affinity of the benzodiazepines quazepam and 2-oxo-quazepam for BZ1 binding site and demonstration of 3H-2-oxo-quazepam as a BZ1 selective radioligand

1988 · W. Billard, G. Crosby, et al. · Life Sciences · 27

Substituted 2-(R)-Methyl piperazines as muscarinic M2 selective ligands

2002 · Joseph A Kozlowski, Guowei Zhou, et al. · Bioorganic & Medicinal Chemistry Letters · 20

Diphenylsulfone muscarinic antagonists: piperidine derivatives with high m2 selectivity and improved potency

2000 · William Billard, Herbert Binch, et al. · Bioorganic & Medicinal Chemistry Letters · 17

Diphenyl sulfoxides as selective antagonists of the muscarinic M2 receptor

2000 · Joseph A Kozlowski, Derek B Lowe, et al. · Bioorganic & Medicinal Chemistry Letters · 16

Sulfhydryl Reactivity: Mechanism of Action of Several Antiviral Compounds—Selenocystine, 4-(2-Propinyloxy)-β-Nitrostyrene, and Acetylaranotin

1974 · William Billard, Edwin Peets · Antimicrobial Agents and Chemotherapy · 15

Benzylidene ketal derivatives as M2 muscarinic receptor antagonists

2000 · Craig D Boyle, Samuel Chackalamannil, et al. · Bioorganic & Medicinal Chemistry Letters · 13

Novel Receptor Specificity of Selected Benzodiazepines

1985 · Allen Barnett, Louis C. Iorio, et al. · Clinical Neuropharmacology · 13

Improving the Oral Efficacy of CNS Drug Candidates: Discovery of Highly Orally Efficacious Piperidinyl Piperidine M2 Muscarinic Receptor Antagonists

2002 · Yuguang Wang, Samuel Chackalamannil, et al. · Journal of Medicinal Chemistry · 11

Potentiation of the hypoglycemic effect of insulin by thiorphan, an enkephalinase inhibitor

1984 · Richard E. Chipkin, William Kreutner, et al. · European Journal of Pharmacology · 11

Metabolic stabilization of benzylidene ketal M2 muscarinic receptor antagonists via halonaphthoic acid substitution

2001 · Craig D. Boyle, Samuel Chackalamannil, et al. · Bioorganic & Medicinal Chemistry Letters · 10

In vitro and in vivo effects of thiorphan: an inhibitor of enkephalinase A.

1982 · R E Chipkin, L C Iorio, et al. · PubMed · 10

Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M2 muscarinic receptor antagonists via benzamide modification

2002 · Craig D. Boyle, Susan F. Vice, et al. · Bioorganic & Medicinal Chemistry Letters · 7

The metabolism of chlorpheniramine maleate in the dog and rat.

1972 · E A Peets, R Weinstein, et al. · PubMed · 7

Relationship of yeast-injection induced changes in brain Met-enkephalin and analgesia

1982 · Richard E. Chipkin, William Billard, et al. · Peptides · 5

Works count: 28

Citation count: 1,363

H-index: 15

I10-index: 22