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Hua‐Chen Chan

Plasma L5 levels are elevated in ischemic stroke patients and enhance platelet aggregation
2015 · Ming-Yi Shen, Fang-Yu Chen, et al. · Blood · 87
Highly electronegative LDL from patients with ST-elevation myocardial infarction triggers platelet activation and aggregation
2013 · Hua-Chen Chan, Liang-Yin Ke, et al. · Blood · 82
Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo
2018 · Yu‐Chen Wang, An‐Sheng Lee, et al. · Aging Cell · 58
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Chemical composition-oriented receptor selectivity of L5, a naturally occurring atherogenic low-density lipoprotein
2011 · Liang-Yin Ke, David A. Engler, et al. · Pure and Applied Chemistry · 38
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Suppressor of cytokine signaling 1 gene expression and polymorphisms in systemic lupus erythematosus
2010 · HC Chan, LY Ke, et al. · Lupus · 36
Role of Low‐Density Lipoprotein in Early Vascular Aging Associated With Systemic Lupus Erythematosus
2020 · Hua‐Chen Chan, Hsiu‐Chuan Chan, et al. · Arthritis & Rheumatology · 33
Electronegative low-density lipoprotein induces cardiomyocyte apoptosis indirectly through endothelial cell-released chemokines
2012 · An-Sheng Lee, Guei-Jane Wang, et al. · APOPTOSIS · 31
Increased APOE glycosylation plays a key role in the atherogenicity of L5 low‐density lipoprotein
2020 · Liang‐Yin Ke, Hua‐Chen Chan, et al. · The FASEB Journal · 30
Molecular and Cellular Mechanisms of Electronegative Lipoproteins in Cardiovascular Diseases
2020 · Liang-Yin Ke, Shi Hui Law, et al. · Biomedicines · 27
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Range of L5 LDL levels in healthy adults and L5’s predictive power in patients with hyperlipidemia or coronary artery disease
2018 · Chih-Sheng Chu, Hua-Chen Chan, et al. · Scientific Reports · 26
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Clinical Significance of Electronegative Low-Density Lipoprotein Cholesterol in Atherothrombosis
2020 · Chih-Sheng Chu, Shi Hui Law, et al. · Biomedicines · 24
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Role of apolipoprotein E in electronegative low-density lipoprotein-induced mitochondrial dysfunction in cardiomyocytes
2020 · Wei-Yu Chen, Yun-Fang Chen, et al. · Metabolism · 24
Increased LDL electronegativity in chronic kidney disease disrupts calcium homeostasis resulting in cardiac dysfunction
2015 · Kuan-Cheng Chang, An-Sheng Lee, et al. · Journal of Molecular and Cellular Cardiology · 23
Untargeted Lipidomic Profiling Reveals Lysophosphatidylcholine and Ceramide as Atherosclerotic Risk Factors in apolipoprotein E Knockout Mice
2023 · Shi-Hui Law, Hua-Chen Chan, et al. · International Journal of Molecular Sciences · 20
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Enhanced Sphingomyelinase Activity Contributes to the Apoptotic Capacity of Electronegative Low-Density Lipoprotein
2016 · Liang-Yin Ke, Hua-Chen Chan, et al. · Journal of Medicinal Chemistry · 20
An Increased Plasma Level of ApoCIII-Rich Electronegative High-Density Lipoprotein May Contribute to Cognitive Impairment in Alzheimer’s Disease
2020 · Hua-Chen Chan, Liang-Yin Ke, et al. · Biomedicines · 18
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Gender disparity in LDL-induced cardiovascular damage and the protective role of estrogens against electronegative LDL
2014 · An-Sheng Lee, Wei-Yu Chen, et al. · Cardiovascular Diabetology · 18
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Electronegative Low-Density Lipoprotein L5 Induces Adipose Tissue Inflammation Associated With Metabolic Syndrome
2017 · Liang-Yin Ke, Hua-Chen Chan, et al. · The Journal of Clinical Endocrinology & Metabolism · 17
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Electronegative low density lipoprotein induces renal apoptosis and fibrosis: STRA6 signaling involved
2016 · Chao-Hung Chen, Chao-Hung Chen, et al. · Journal of Lipid Research · 16
Efficiency comparison of PGBR extract and γ‐oryzanol in antioxidative stress and anti‐inflammatory properties against metabolic syndrome
2019 · Hui‐Li Lin, Shih‐Hsiung Lin, et al. · Journal of Food Biochemistry · 14
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Next-Generation Sequencing Profiles of the Methylome and Transcriptome in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis
2019 · Chia-Chun Tseng, Yuan-Zhao Lin, et al. · Journal of Clinical Medicine · 14
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Increased Expression of Suppressor of Cytokine Signaling 1 mRNA in Patients With Rheumatoid Arthritis
2010 · Hua‐Chen Chan, Liang‐Yin Ke, et al. · The Kaohsiung Journal of Medical Sciences · 14
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Four Statin Benefit Groups Defined by The 2013 ACC/AHA New Cholesterol Guideline are Characterized by Increased Plasma Level of Electronegative Low-Density Lipoprotein.
2016 · Chih-Sheng Chu, Liang-Yin Ke, et al. · PubMed · 12
Disruption of retinoid homeostasis induces RBP4 overproduction in diabetes: O-GlcNAcylation involved
2020 · Shyi-Jang Shin, Chao-Hung Chen, et al. · Metabolism · 11
Electronegative LDL-mediated cardiac electrical remodeling in a rat model of chronic kidney disease
2017 · An-Sheng Lee, Wei-Yu Chen, et al. · Scientific Reports · 11
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Works count: 51
Citation count: 751
H-index: 17
I10-index: 25
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