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Philip Hasel
Institutions:
UK Dementia Research Institute,
University of Edinburgh
Observed institutions:
NYU Langone Health,
UK Dementia Research Institute,
Simons Initiative for the Developing Brain,
New York University,
University of Edinburgh
ORCID:
0000-0003-4378-3685
Observed ORCID:
0000-0003-4378-3685
OpenAlex ID:
A5044428518
Works
24
Awards
1
Neuroinflammatory astrocyte subtypes in the mouse brain
2021
·
Philip Hasel
, Indigo V. L. Rose
, et al.
·
Nature Neuroscience
·
636
Neurotoxic reactive astrocytes induce cell death via saturated lipids
2021
·
Kevin A. Guttenplan
, Maya K. Weigel
, et al.
·
Nature
·
610
Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease
2022
·
Jessica S. Sadick
, Michael R. O’Dea
, et al.
·
Neuron
·
458
PDF
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism
2017
·
Philip Hasel
, Owen Dando
, et al.
·
Nature Communications
·
316
PDF
Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2
2015
·
Karen F.S. Bell
, Bashayer Al-Mubarak
, et al.
·
Nature Communications
·
199
PDF
Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system
2015
·
Paul S. Baxter
, Karen F.S. Bell
, et al.
·
Nature Communications
·
144
PDF
Molecular and metabolic heterogeneity of astrocytes and microglia
2023
·
Philip Hasel
, William H. Aisenberg
, et al.
·
Cell Metabolism
·
136
Astrocytes
2021
·
Philip Hasel
, Shane A. Liddelow
·
Current Biology
·
104
PDF
Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease
2022
·
Emilie L. Castranio
, Philip Hasel
, et al.
·
Alzheimer s & Dementia
·
77
PDF
Mitochondrial Calcium Uptake Modulates Synaptic Vesicle Endocytosis in Central Nerve Terminals
2015
·
Jamie Roslin Keynes Marland
, Philip Hasel
, et al.
·
Journal of Biological Chemistry
·
77
PDF
Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates
2025
·
Philip Hasel
, Melissa L. Cooper
, et al.
·
Cell Reports
·
52
The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences
2018
·
Sean McKay
, Tomás J. Ryan
, et al.
·
Cell Reports
·
47
PDF
Selective dendritic susceptibility to bioenergetic, excitotoxic and redox perturbations in cortical neurons
2014
·
Philip Hasel
, Sean Mckay
, et al.
·
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
·
39
PDF
Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ Signaling
2016
·
Nóra M. Márkus
, Philip Hasel
, et al.
·
PLoS ONE
·
36
PDF
Mixed-species RNA-seq for elucidation of non-cell-autonomous control of gene transcription
2018
·
Jing Qiu
, Owen Dando
, et al.
·
Nature Protocols
·
30
Are we there yet? Exploring astrocyte heterogeneity one cell at a time
2024
·
Michael R. O'Dea
, Philip Hasel
·
Glia
·
28
PDF
Isoform-dependent APOE secretion modulates neuroinflammation
2021
·
Philip Hasel
, Shane A. Liddelow
·
Nature Reviews Neurology
·
21
Temporal and spatial analysis of astrocytes following stroke identifies novel drivers of reactivity
2023
·
Rachel D Kim
, Anne E Marchildon
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
20
PDF
Correction: Author Correction: Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism
2018
·
Philip Hasel
, Owen Dando
, et al.
·
Nature Communications
·
8
PDF
Erratum: Corrigendum: Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system
2017
·
Paul S. Baxter
, Karen F. S. Bell
, et al.
·
Nature Communications
·
3
The role of neuronal activity in regulating metabolism in mouse and human astrocytes
2017
·
Zoeb Jiwaji
, Philip Hasel
, et al.
·
The Lancet
·
1
Astrocytes transform the transcriptomic and epigenetic landscape of developing cortical neurons to promote activity via intrinsic excitability control
2026
·
Alison C. Todd
, Jing Qiu
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
Multi‐modal sequencing analysis of astrocytes in human and mouse reveals strategically positioned novel reactive sub‐states
2022
·
Philip Hasel
, Michael O'Dea
, et al.
·
Alzheimer s & Dementia
Investigation into the destructive and adaptive responses of neural cells to stress
2017
·
Philip Hasel
·
ERA
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Works count:
24
Citation count:
3,042
H-index:
18
I10-index:
18
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