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Sorin Tunaru
Observed names:
S Tunaru,
S. Tunaru,
Tunaru, S.
Institutions:
Institute of Biochemistry,
Romanian Academy
Observed institutions:
Max Planck Society,
Heidelberg University,
Max Planck Institute for Heart and Lung Research,
Bioterra University Bucharest,
Institute of Biochemistry,
Romanian Academy
show all 6
ORCID:
0000-0002-6005-1737
Observed ORCID:
0000-0002-6005-1737
OpenAlex ID:
A5044617923
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
2003
·
Sorin Tunaru
, Jukka Kero
, et al.
·
Nature Medicine
·
805
An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81
2010
·
Kashan Ahmed
, Sorin Tunaru
, et al.
·
Cell Metabolism
·
469
PDF
Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes
2015
·
Cong Tang
, Kashan Ahmed
, et al.
·
Nature Medicine
·
341
GPR109A, GPR109B and GPR81, a family of hydroxy-carboxylic acid receptors
2009
·
Kashan Ahmed
, Sorin Tunaru
, et al.
·
Trends in Pharmacological Sciences
·
260
Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP 3 receptors
2012
·
Sorin Tunaru
, Till F. Althoff
, et al.
·
Proceedings of the National Academy of Sciences
·
221
PDF
Nicotinic acid– and monomethyl fumarate–induced flushing involves GPR109A expressed by keratinocytes and COX-2–dependent prostanoid formation in mice
2010
·
Julien Hanson
, Andreas Gille
, et al.
·
Journal of Clinical Investigation
·
204
PDF
Conserved MIP receptor–ligand pair regulates Platynereis larval settlement
2013
·
Markus Conzelmann
, Elizabeth A. Williams
, et al.
·
Proceedings of the National Academy of Sciences
·
157
PDF
Characterization of Determinants of Ligand Binding to the Nicotinic Acid Receptor GPR109A (HM74A/PUMA-G)
2005
·
Sorin Tunaru
, Jens Lättig
, et al.
·
Molecular Pharmacology
·
131
Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development
2007
·
Jukka Kero
, Kashan Ahmed
, et al.
·
Journal of Clinical Investigation
·
127
PDF
Nicotinic acid (niacin): new lipid-independent mechanisms of action and therapeutic potentials
2011
·
Martina Lukasova
, Julien Hanson
, et al.
·
Trends in Pharmacological Sciences
·
112
20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1
2018
·
Sorin Tunaru
, Remy Bonnavion
, et al.
·
Nature Communications
·
98
PDF
Deorphanization of GPR109B as a Receptor for the β-Oxidation Intermediate 3-OH-octanoic Acid and Its Role in the Regulation of Lipolysis
2009
·
Kashan Ahmed
, Sorin Tunaru
, et al.
·
Journal of Biological Chemistry
·
95
Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63
2003
·
Anke Niedernberg
, Sorin Tunaru
, et al.
·
Cellular Signalling
·
73
Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis
2017
·
K. Schmitz
, R. Brunkhorst
, et al.
·
Acta Neuropathologica Communications
·
64
PDF
The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity
2017
·
Stephan W. Hohmann
, Carlo Angioni
, et al.
·
Scientific Reports
·
64
PDF
A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development
2019
·
Christian S. M. Helker
, Sri-Teja Mullapudi
, et al.
·
Development
·
43
PDF
Arachidonic Acid Metabolite 19(S)-HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor
2016
·
Sorin Tunaru
, Ramesh Chennupati
, et al.
·
PLoS ONE
·
35
PDF
Comparative Analysis of Functional Assays for Characterization of Agonist Ligands at G Protein–Coupled Receptors
2003
·
Anke Niedernberg
, Sorin Tunaru
, et al.
·
SLAS DISCOVERY
·
33
PDF
The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons
2017
·
Sebastian Zinn
, Marco Sisignano
, et al.
·
Journal of Biological Chemistry
·
31
Nicotinamide Limits Replication of Mycobacterium tuberculosis and Bacille Calmette-Guérin Within Macrophages
2019
·
Jason D Simmons
, Glenna J Peterson
, et al.
·
The Journal of Infectious Diseases
·
23
PDF
A novel luminescence-based method for the detection of functionally active antibodies to muscarinic acetylcholine receptors of the M3 type (mAchR3) in patients' sera
2014
·
B Preuss
, S Tunaru
, et al.
·
Clinical & Experimental Immunology
·
21
The antimalarial artemisinin is a non-electrophilic agonist of the transient receptor potential ankyrin type 1 receptor-channel
2022
·
Debora-Elena Huţanu
, George Oprita
, et al.
·
European Journal of Pharmacology
·
8
Oleic acid released by sensory neurons inhibits TRPV1-mediated thermal hypersensitivity via GPR40
2024
·
Maksim Sendetski
, Saskia Wedel
, et al.
·
iScience
·
7
Statins activate temperature-gated transient receptor potential ion channels
2025
·
George Oprita
, Dan Domocos
, et al.
·
European Journal of Pharmacology
·
3
Inhibition of TRPM8 function by prostacyclin receptor agonists requires coupling to Gq/11 proteins
2023
·
Cosmin Trif
, Alexandra‐Maria Banica
, et al.
·
British Journal of Pharmacology
·
2
PDF
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Works count:
35
Citation count:
3,431
H-index:
21
I10-index:
21
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