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José Dias

New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease
2019 · Irina Zueva, José Dias, et al. · Neuropharmacology · 89
Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents
2018 · Gianluca Santoni, Julien de Sousa, et al. · Journal of Medicinal Chemistry · 60
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The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives
2024 · Camille Voros, José Dias, et al. · Chemico-Biological Interactions · 39
Association of Mitochondrial Lysyl-tRNA Synthetase with HIV-1 GagPol Involves Catalytic Domain of the Synthetase and Transframe and Integrase Domains of Pol
2011 · Lydia Kobbi, Guillaume Octobre, et al. · Journal of Molecular Biology · 36
Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase
2016 · Julien Renou, José Dias, et al. · RSC Advances · 33
From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series
2022 · Anže Meden, Damijan Knez, et al. · European Journal of Medicinal Chemistry · 32
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Small-angle X-ray Solution Scattering Study of the Multi-aminoacyl-tRNA Synthetase Complex Reveals an Elongated and Multi-armed particle
2013 · José Dias, Louis Renault, et al. · Journal of Biological Chemistry · 31
An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice
2016 · André-Guilhem Calas, José Dias, et al. · Chemico-Biological Interactions · 27
Discovery of multifunctional anti-Alzheimer’s agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters
2021 · Anna Pasieka, Dawid Panek, et al. · European Journal of Medicinal Chemistry · 25
Activation of Human Mitochondrial Lysyl-tRNA Synthetase upon Maturation of Its Premitochondrial Precursor
2012 · José Dias, Guillaume Octobre, et al. · Biochemistry · 22
Insights into the Regulation of the Ryanodine Receptor: Differential Effects of Mg2+and Ca2+on ATP Binding
2006 · José M. Dias, Csaba Szegedi, et al. · Biochemistry · 21
A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning
2022 · Ophélie Da Silva, Nicolas Probst, et al. · Journal of Medicinal Chemistry · 20
Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime
2020 · André-Guilhem Calas, Anne-Sophie Hanak, et al. · Biomolecules · 19
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Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases
2021 · Daniel Chavarria, Ophelie Da Silva, et al. · Antioxidants · 17
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Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
2021 · Lukas Gorecki, Vendula Hepnarova, et al. · Archives of Toxicology · 16
Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening
2020 · Jared A. Miles, Jeevak S. Kapure, et al. · Bioorganic & Medicinal Chemistry Letters · 12
Grid‐Type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions
2022 · Florian Nachon, Xavier Brazzolotto, et al. · ChemBioChem · 11
Lead Optimization of a Butyrylcholinesterase Inhibitor for the Treatment of Alzheimer’s Disease
2025 · Urban Košak, Nika Strašek Benedik, et al. · Journal of Medicinal Chemistry · 10
Effects of Small Molecule Modulators on ATP Binding to Skeletal Ryanodine Receptor
2009 · José M. Dias, Pia D. Vogel · The Protein Journal · 9
Inhibition of Human Cholinesterases and in vitro β‐Amyloid Aggregation by Rationally Designed Peptides
2023 · Ivan Sanchis, Roque Spinelli, et al. · ChemMedChem · 8
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Characterization of association of human mitochondrial lysyl-tRNA synthetase with HIV-1 Pol and tRNA3Lys
2018 · Fawzi Khoder-Agha, José M. Dias, et al. · BMC Biochemistry · 8
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Discovery of drug‐like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database
2021 · Jared A. Miles, Jia Hui Ng, et al. · Chemical Biology & Drug Design · 7
Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38α Mitogen-Activated Protein Kinase Inhibitors
2025 · Svit Ferjančič Benetik, Matic Proj, et al. · Journal of Medicinal Chemistry · 6
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N-Propargylpyrrolidine-based butyrylcholinesterase and monoamine oxidase inhibitors
2025 · Urban Košak, Damijan Knez, et al. · Chemico-Biological Interactions · 6
Chemoselective Hydrogenation of 6‐Alkynyl‐3‐fluoro‐2‐pyridinaldoximes: Access to First‐in‐Class 6‐Alkyl‐3‐Fluoro‐2‐pyridinaldoxime Scaffolds as New Reactivators of Sarin‐Inhibited Human Acetylcholinesterase with Increased Blood–Brain Barrier Permeability
2020 · Jagadeesh Yerri, José Dias, et al. · Chemistry - A European Journal · 6
Works count: 59
Citation count: 589
H-index: 15
I10-index: 18
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