Get started
Author

Valerie M. Chappe

Observed names: Chappe, V., V Chappe, V. Chappe, VALERIE CHAPPE, Valerie Chappe, Valérie Chappe, Valérie M. Chappe
ORCID: 0000-0002-8339-1363
Observed ORCID: 0000-0002-8339-1363
OpenAlex ID: A5044766852
Development of Substituted Benzo[c]quinolizinium Compounds as Novel Activators of the Cystic Fibrosis Chloride Channel
1999 · Frédéric Becq, Yvette Mettey, et al. · Journal of Biological Chemistry · 115
PDF
ClC Channels and Transporters: Structure, Physiological Functions, and Implications in Human Chloride Channelopathies
2017 · Diogo R. Poroca, Ryan M. Pelis, et al. · Frontiers in Pharmacology · 110
PDF
Animal Models in the Pathophysiology of Cystic Fibrosis
2019 · Anna Semaniakou, Roger P. Croll, et al. · Frontiers in Pharmacology · 106
PDF
Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA
2003 · V Chappe, D A Hinkson, et al. · The Journal of Physiology · 96
The role of ghrelin in the regulation of glucose homeostasis
2016 · Bader N. Alamri, Kyungsoo Shin, et al. · Hormone Molecular Biology and Clinical Investigation · 93
PDF
Phosphorylation of CFTR by PKA promotes binding of the regulatory domain
2005 · Valerie Chappe, Thomas Irvine, et al. · The EMBO Journal · 86
PDF
Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator
2003 · Valerie Chappe, Deborah A. Hinkson, et al. · Proceedings of the National Academy of Sciences · 86
Structural basis for specificity and potency of xanthine derivatives as activators of the CFTR chloride channel
1998 · V. Chappe, Y. Mettey, et al. · British Journal of Pharmacology · 65
PDF
PKC phosphorylation modulates PKA-dependent binding of the R domain to other domains of CFTR
2008 · Gage Seavilleklein, Noha Amer, et al. · American Journal of Physiology-Cell Physiology · 40
VIP regulates CFTR membrane expression and function in Calu-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1- and PKCε-dependent manner
2014 · Walaa Alshafie, Frederic G. Chappe, et al. · American Journal of Physiology-Cell Physiology · 27
Vasoactive Intestinal Peptide Increases Cystic Fibrosis Transmembrane Conductance Regulator Levels in the Apical Membrane of Calu-3 Cells through a Protein Kinase C-Dependent Mechanism
2008 · Frédéric Chappe, Matthew E. Loewen, et al. · Journal of Pharmacology and Experimental Therapeutics · 25
Pharmacological and Signaling Properties of Endogenous P2Y1 Receptors in Cystic Fibrosis Transmembrane Conductance Regulator-Expressing Chinese Hamster Ovary Cells
2004 · Brice Marcet, Valérie Chappe, et al. · Journal of Pharmacology and Experimental Therapeutics · 24
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Confers Glibenclamide Sensitivity to Outwardly Rectifying Chloride Channel (ORCC) in Hi-5 Insect Cells
1999 · M. Julien, B. Verrier, et al. · The Journal of Membrane Biology · 23
Rescue of Functional F508del Cystic Fibrosis Transmembrane Conductance Regulator by Vasoactive Intestinal Peptide in the Human Nasal Epithelial Cell Line JME/CF15
2009 · Sara Rafferty, Nicole Alcolado, et al. · Journal of Pharmacology and Experimental Therapeutics · 22
Cystic fibrosis transmembrane conductance regulator dysfunction in VIP knockout mice
2014 · Nicole G. Alcolado, Dustin J. Conrad, et al. · American Journal of Physiology-Cell Physiology · 17
Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA
2003 · V. Chappe, D. A. Hinkson, et al. · The Journal of Physiology · 16
Iron chelation as novel treatment for lung inflammation in cystic fibrosis
2017 · Maral Aali, Alexa Caldwell, et al. · Medical Hypotheses · 14
Disrupted local innervation results in less VIP expression in CF mice tissues
2020 · Anna Semaniakou, Sarah Brothers, et al. · Journal of Cystic Fibrosis · 12
VIP-dependent increase in F508del-CFTR membrane localization is mediated by PKCε
2011 · Nicole Alcolado, Dustin J. Conrad, et al. · American Journal of Physiology-Cell Physiology · 12
VIP reduction in the pancreas of F508del homozygous CF mice and early signs of Cystic Fibrosis Related Diabetes (CFRD)
2021 · Anna Semaniakou, Frederic Chappe, et al. · Journal of Cystic Fibrosis · 10
Negative Regulation of CFTR Activity by Extracellular ATP Involves P2Y2 Receptors in CFTR-expressing CHO Cells
2003 · B. Marcet, V. Chappe, et al. · The Journal of Membrane Biology · 10
Anti-Inflammatory Effects of the Iron Chelator, DIBI, in Experimental Acute Lung Injury
2022 · Christian Lehmann, Nazli Alizadeh-Tabrizi, et al. · Molecules · 9
PDF
Lung-Protective Ventilation Attenuates Mechanical Injury While Hypercapnia Attenuates Biological Injury in a Rat Model of Ventilator-Associated Lung Injury
2022 · Nada Ismaiel, Sara Whynot, et al. · Frontiers in Physiology · 9
PDF
Changes in the R‐region interactions depend on phosphorylation and contribute to PKA and PKC regulation of the cystic fibrosis transmembrane conductance regulator chloride channel
2019 · Diogo R. Poroca, Noha Amer, et al. · FASEB BioAdvances · 9
PDF
Working to Have a Normal Life With Cystic Fibrosis in an Adherence-Driven Health Care System
2019 · Marilyn Macdonald, Ariella Lang, et al. · Respiratory Care · 3
PDF
Works count: 38
Citation count: 1,048
H-index: 16
I10-index: 21
Year
Topic
Type