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Pierre Laurin

Observed names: P. Laurin, PIERRE LAURIN
OpenAlex ID: A5045052502
A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors
2018 · Lyne Gagnon, Martin Leduc, et al. · American Journal Of Pathology · 138
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Phase 2 clinical trial of PBI-4050 in patients with idiopathic pulmonary fibrosis
2018 · Nasreen Khalil, Helene Manganas, et al. · European Respiratory Journal · 109
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Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency
2018 · Amy D. Shapiro, Charles Nakar, et al. · Blood · 48
Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver disease
2020 · Jean-Christophe Simard, Jean-François Thibodeau, et al. · Scientific Reports · 33
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Fatty acid receptor modulator PBI-4050 inhibits kidney fibrosis and improves glycemic control
2018 · Yan Li, Sungjin Chung, et al. · JCI Insight · 32
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PBI-4050 Reduces Stellate Cell Activation and Liver Fibrosis through Modulation of Intracellular ATP Levels and the Liver Kinase B1/AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway
2018 · Brigitte Grouix, Francois Sarra-Bournet, et al. · Journal of Pharmacology and Experimental Therapeutics · 31
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PBI-4050 reduces pulmonary hypertension, lung fibrosis, and right ventricular dysfunction in heart failure
2019 · Quang T Nguyen, Mohamed J Nsaibia, et al. · Cardiovascular Research · 30
Fourteen-Day Evolution of COVID-19 Symptoms during the Third Wave in Nonvaccinated Subjects and Effects of Hesperidin Therapy: A Randomized, Double-Blinded, Placebo-Controlled Study
2022 · Jocelyn Dupuis, Pierre Laurin, et al. · Evidence-based Complementary and Alternative Medicine · 16
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Design and Synthesis of New 1,3,5‐Trisubstituted Triazines for the Treatment of Cancer and Inflammation
2018 · Boulos Zacharie, Shaun D. Abbott, et al. · ChemistryOpen · 14
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Fourteen-days Evolution of COVID-19 Symptoms During the Third Wave in Non-vaccinated Subjects and Effects of Hesperidin Therapy: A randomized, double-blinded, placebo-controlled study
2021 · Jocelyn Dupuis, Pierre Laurin, et al. · medRxiv · 3
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P72 Oral Treatment With Pbi-4050, a Novel First-in-class Anti-fibrotic Compound, Reduces Hepatic Fibrosis and Hepatocellular Carcinoma
2014 · L. Gagnon, L. Geerts, et al. · Journal of Hepatology · 3
Fo008fatty Acid Receptors Gpr40/gpr84: Two Promising Targets in Kidney Fibrosis
2019 · Lyne Gagnon, Martin Leduc, et al. · Nephrology Dialysis Transplantation · 2
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Sp345activation of the Free-fatty Acid Receptor Gpr40 Improves Anemia in Mouse Models of Kidney Disease Via a Novel Epo-independent Mechanism of Action
2019 · Lyne Gagnon, Jean-Francois Thibodeau, et al. · Nephrology Dialysis Transplantation · 2
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Abstract 19469: PBI-4050 Reduces Cardiovascular Biomarkers in Type II Diabetic Patients With Metabolic Syndrome
2016 · Pierre Laurin, Brigitte Grouix, et al. · Circulation · 2
Sp102oral Treatment With Pbi-4050 Reduces Kidney Fibrosis
2015 · Lyne Gagnon, Martin Leduc, et al. · Nephrology Dialysis Transplantation · 2
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Oral Treatment with PBI-1402 Increases Hemoglobin Level and Red Blood Cell Count: A Novel Approach to Treating Chemotherapy-Induced Anemia.
2007 · Lyne Gagnon, Jean Barabe, et al. · Blood · 2
PBI-4547 Improves Glucose Metabolism and Insulin Resistance, and Reduces Liver Damage in a High-Fat Diet Mouse Model of Obesity and Metabolic Syndrome
2018 · MARTIN LEDUC, BRIGITTE GROUIX, et al. · Diabetes · 1
PBI-4050 reduces expression of fibrosis biomarkers in the BioMAP SAEMyoF primary human small airway epithelial cells and lung myofibroblasts system
2017 · Lyne Gagnon, Brigitte Grouix, et al. · 1
PBI-4050 reduces liver damage and fibrosis in a high-fat diet mouse model of obesity and metabolic syndrome
2017 · B. Grouix, F. Sarra-Bournet, et al. · Journal of Hepatology · 1
Sp251treatment Efficacy of Pbi-4050, an Orally Active Antifibrotic Agent, Can Be Monitored by Following Urinary Biomarkers in 5/6-nephrectomized Rats
2016 · Lyne Gagnon, François Sarra-Bournet, et al. · Nephrology Dialysis Transplantation · 1
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PBI-4050 Decreases Hepatic Stellate Cell Activation and Ameliorates Fibrosis in Carbon Tetrachloride (CCL4)- Induced Hepatic Fibrosis Model
2016 · F. Sarra-Bournet, B. Grouix, et al. · Journal of Hepatology · 1
Fp445pbi-4050 Protects Against Renal and Pancreatic Fibrosis in Type Ii Diabetes
2015 · Lyne Gagnon, Ming-Zhi Zhang, et al. · Nephrology Dialysis Transplantation · 1
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Renal fibrosis and progression
2013 · M. Leduc, L. Gervais, et al. · Nephrology Dialysis Transplantation · 1
PBI-1402: A New Candidate for the Treatment of Anemia.
2006 · Lyne Gagnon, Jean Barabé, et al. · Blood · 1
ING-006 Modulation of GPR40 and GPR84: The Bright/Dark Side Targets in IPF Pathogenesis
2025 · L. Gagnon, K. Brochu-Gaudreau, et al. · American Journal of Respiratory and Critical Care Medicine
Works count: 49
Citation count: 475
H-index: 9
I10-index: 9
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