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Florian Kloß
Observed names:
Florian Kloss,
Kloss, Florian,
Kloß, Florian
Institution:
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)
Observed institutions:
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI),
BioControl Jena (Germany),
Friedrich Schiller University Jena
ORCID:
0000-0003-2283-1457
Observed ORCID:
0000-0003-2283-1457
OpenAlex ID:
A5045286945
Antibiotics from neglected bacterial sources
2013
·
Sacha J. Pidot
, Sébastien Coyne
, et al.
·
International Journal of Medical Microbiology
·
136
The Molecular Basis of Conjugated Polyyne Biosynthesis in Phytopathogenic Bacteria
2014
·
Claudia Ross
, Kirstin Scherlach
, et al.
·
Angewandte Chemie International Edition
·
85
Metal‐Free Synthesis of Pharmaceutically Important Biaryls by Photosplicing
2018
·
Florian Kloss
, Toni Neuwirth
, et al.
·
Angewandte Chemie International Edition
·
64
In Vivo Dearomatization of the Potent Antituberculosis Agent BTZ043 via Meisenheimer Complex Formation
2017
·
Florian Kloss
, Viktor Krchnak
, et al.
·
Angewandte Chemie International Edition
·
63
Antiterminator‐Mediated Unveiling of Cryptic Polythioamides in an Anaerobic Bacterium
2012
·
Swantje Behnken
, Thorger Lincke
, et al.
·
Angewandte Chemie International Edition
·
55
Metal‐Free 1,5‐Regioselective Azide–Alkyne [3+2]‐Cycloaddition
2011
·
Florian Kloss
, Uwe Köhn
, et al.
·
Chemistry - An Asian Journal
·
47
Mode of action of closthioamide: the first member of the polythioamide class of bacterial DNA gyrase inhibitors
2015
·
Alina Iulia Chiriac
, Florian Kloss
, et al.
·
Journal of Antimicrobial Chemotherapy
·
46
Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke
2022
·
Lynn Bitar
, Timo Uphaus
, et al.
·
Science Translational Medicine
·
38
AgRP neurons control feeding behaviour at cortical synapses via peripherally derived lysophospholipids
2022
·
Heiko Endle
, Guilherme Horta
, et al.
·
Nature Metabolism
·
37
Formation of a Dinuclear Copper(I) Complex from the Clostridium‐Derived Antibiotic Closthioamide
2013
·
Florian Kloss
, Sacha Pidot
, et al.
·
Angewandte Chemie International Edition
·
37
Highly Efficient Total Synthesis of the Clostridium‐Derived anti‐MRSA Antibiotic Closthioamide
2011
·
Florian Kloss
, Thorger Lincke
, et al.
·
European Journal of Organic Chemistry
·
35
Safety, bactericidal activity, and pharmacokinetics of the antituberculosis drug candidate BTZ-043 in South Africa (PanACEA-BTZ-043–02): an open-label, dose-expansion, randomised, controlled, phase 1b/2a trial
2025
·
Norbert Heinrich
, Veronique de Jager
, et al.
·
The Lancet Microbe
·
30
PDF
Reconstitution of Iterative Thioamidation in Closthioamide Biosynthesis Reveals Tailoring Strategy for Nonribosomal Peptide Backbones
2019
·
Kyle L. Dunbar
, Maria Dell
, et al.
·
Angewandte Chemie International Edition
·
27
PDF
Disruption of Membrane Integrity by the Bacterium-Derived Antifungal Jagaricin
2019
·
Daniel Fischer
, Guido Gessner
, et al.
·
Antimicrobial Agents and Chemotherapy
·
26
PDF
The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis
2025
·
Andreas Römpp
, Axel Treu
, et al.
·
Nature Communications
·
23
PDF
Mapping of the Modular Closthioamide Architecture Reveals Crucial Motifs of Polythioamide Antibiotics
2014
·
Florian Kloss
, Alina Iulia Chiriac
, et al.
·
Chemistry - A European Journal
·
22
Natural products in antibiotic development: is the success story over?
2022
·
Freddy A Bernal
, Peter Hammann
, et al.
·
Current Opinion in Biotechnology
·
19
The Molecular Basis of Conjugated Polyyne Biosynthesis in Phytopathogenic Bacteria
2014
·
Claudia Ross
, Kirstin Scherlach
, et al.
·
Angewandte Chemie
·
19
Antiterminator‐Mediated Unveiling of Cryptic Polythioamides in an Anaerobic Bacterium
2012
·
Swantje Behnken
, Thorger Lincke
, et al.
·
Angewandte Chemie
·
19
Metal‐Free Aryl Cross‐Coupling Directed by Traceless Linkers
2019
·
Veit G. Haensch
, Toni Neuwirth
, et al.
·
Chemistry - A European Journal
·
18
PDF
Investigation of amino acid containing [FeFe] hydrogenase models concerning pendant base effects
2009
·
Ulf-Peter Apfel
, Christian R. Kowol
, et al.
·
Journal of Inorganic Biochemistry
·
18
Deazaflavin metabolite produced by endosymbiotic bacteria controls fungal host reproduction
2024
·
Ingrid Richter
, Mahmudul Hasan
, et al.
·
The ISME Journal
·
17
Pharmacokinetics and Efficacy of the Benzothiazinone BTZ-043 against Tuberculous Mycobacteria inside Granulomas in the Guinea Pig Model
2023
·
Emmelie Eckhardt
, Yan Li
, et al.
·
Antimicrobial Agents and Chemotherapy
·
15
PDF
Metal‐Free Synthesis of Pharmaceutically Important Biaryls by Photosplicing
2018
·
Florian Kloss
, Toni Neuwirth
, et al.
·
Angewandte Chemie
·
15
Formation of a Dinuclear Copper(I) Complex from the Clostridium‐Derived Antibiotic Closthioamide
2013
·
Florian Kloss
, Sacha Pidot
, et al.
·
Angewandte Chemie
·
15
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Works count:
69
Citation count:
1,075
H-index:
19
I10-index:
28
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