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Igor José dos Santos Nascimento

Observed names: Igor José dos Santos Nascimentos, Igor J. S. Nascimento, Igor J. dos Santos Nascimento, Igor Jose dos Santos Nascimento, Igor José Dos Santos Nascimento, Igor José do Santos Nascimento, Igor José dos S. Nascimento, Igor José dos Santos Nascimento, Igor Nascimento, Igor. J.S. Nascimento, Nascimento, Igor J. S.
ORCID: 0000-0002-2664-4336
Observed ORCID: 0000-0002-2664-4336
OpenAlex ID: A5045328085
The New Era of Drug Discovery: The Power of Computer-aided Drug Design (CADD)
2022 · Igor José dos Santos Nascimento, Thiago Mendonça de Aquino, et al. · Letters in Drug Design & Discovery · 116
Drug Repurposing: A Strategy for Discovering Inhibitors against Emerging Viral Infections
2020 · Igor José dos Santos Nascimento, Thiago Mendonça de Aquino, et al. · Current Medicinal Chemistry · 63
Computer-aided design of 1,4-naphthoquinone-based inhibitors targeting cruzain and rhodesain cysteine proteases
2021 · Leandro Rocha Silva, Ari Souza Guimarães, et al. · Bioorganic & Medicinal Chemistry · 59
Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors
2021 · Igor José dos Santos Nascimento, Paulo Fernando da Silva Santos-Júnior, et al. · European Journal of Medicinal Chemistry · 50
Cruzain and Rhodesain Inhibitors: Last Decade of Advances in Seeking for New Compounds Against American and African Trypanosomiases
2021 · Igor José dos Santos Nascimento, Thiago Mendonça de Aquino, et al. · Current Topics in Medicinal Chemistry · 48
Advances in Computational Methods to Discover New NS2B-NS3 Inhibitors Useful Against Dengue and Zika Viruses
2022 · Igor José dos Santos Nascimento, Érica Erlanny da Silva Rodrigues, et al. · Current Topics in Medicinal Chemistry · 46
Exploring N-myristoyltransferase as a promising drug target against parasitic neglected tropical diseases
2023 · Igor José dos Santos Nascimento, Misael de Azevedo Teotônio Cavalcanti, et al. · European Journal of Medicinal Chemistry · 39
Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes
2021 · Thiago M. de Aquino, Paulo H. B. França, et al. · Medicinal Chemistry · 38
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Dynamic Cross-Correlation Matrix (DCCM) Reveals New Insights to Discover New NLRP3 Inhibitors Useful as Anti-Inflammatory Drugs
2022 · Igor José dos Santos Nascimento, Marianny De Souza, et al. · ECMC 2022 · 37
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TNF-α Inhibitors from Natural Compounds: An Overview, CADD Approaches, and their Exploration for Anti-inflammatory Agents
2021 · Edeildo Ferreira da Silva-Júnior, Igor José dos Santos Nascimento · Combinatorial Chemistry & High Throughput Screening · 32
Repurposing FDA-approved Drugs Targeting SARS-CoV2 3CL pro : A Study by Applying Virtual Screening, Molecular Dynamics, MM-PBSA Calculations and Covalent Docking
2022 · Igor José dos Santos Nascimento, Thiago Mendonça de Aquino, et al. · Letters in Drug Design & Discovery · 29
Computer-Aided Drug Design of Anti-inflammatory Agents Targeting Microsomal Prostaglandin E2Synthase-1 (mPGES-1)
2022 · Igor José dos Santos Nascimento, Thiago Mendonça de Aquino, et al. · Current Medicinal Chemistry · 28
Molecular Docking and Dynamics Simulation Studies of a Dataset of NLRP3 Inflammasome Inhibitors
2022 · Igor J. dos Santos Nascimento, Thiago M. de Aquino, et al. · Recent Advances in Inflammation & Allergy Drug Discovery · 27
The new psychoactive substances 25H-NBOMe and 25H-NBOH induce abnormal development in the zebrafish embryo and interact in the DNA major groove
2021 · Wellington Alves de Barros, Camila da Silva Nunes, et al. · Current Research in Toxicology · 26
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The Power of Molecular Dynamics Simulations and Their Applications to Discover Cysteine Protease Inhibitors
2023 · Igor José dos Santos Nascimento, Joilly Nilce Santana Gomes, et al. · Mini-Reviews in Medicinal Chemistry · 25
ACW-02 an Acridine Triazolidine Derivative Presents Antileishmanial Activity Mediated by DNA Interaction and Immunomodulation
2023 · Sonaly Lima Albino, Willian Charles da Silva Moura, et al. · Pharmaceuticals · 24
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Molecular Modeling Targeting Transmembrane Serine Protease 2 (TMPRSS2) as an Alternative Drug Target Against Coronaviruses
2021 · Igor José dos Santos Nascimento, Edeildo Ferreira da Silva-Júnior, et al. · Current Drug Targets · 24
Strategies in Medicinal Chemistry to Discover New Hit Compounds against Ebola Virus: Challenges and Perspectives in Drug Discovery
2022 · Igor José dos Santos Nascimento, Paulo Fernando da Silva Santos-Júnior, et al. · Mini-Reviews in Medicinal Chemistry · 20
Synthesis of hybrids thiazole–quinoline, thiazole–indole and their analogs: in vitro anti-proliferative effects on cancer cell lines, DNA binding properties and molecular modeling
2021 · Paulo Fernando da S. Santos-Junior, Igor José dos S. Nascimento, et al. · New Journal of Chemistry · 20
Molecular Modeling Applied to Design of Cysteine Protease Inhibitors – A Powerful Tool for the Identification of Hit Compounds Against Neglected Tropical Diseases
2020 · Igor José dos Santos Nascimento, Thiago Mendonça de Aquino, et al. · Frontiers in computational chemistry · 20
Molecular Dynamics Simulations in Drug Discovery
2024 · Igor José dos Santos Nascimento, Ricardo Olimpio de Moura · Mini-Reviews in Medicinal Chemistry · 19
Targeting cysteine protease B to discover antileishmanial drugs: Directions and advances
2025 · Éric de Oliveira Rios, Sonaly Lima Albino, et al. · European Journal of Medicinal Chemistry · 15
Anticancer Drug Discovery from Natural Compounds Targeting PI3K/AKT/mTOR Signaling Pathway
2024 · Manuele Figueiredo da Silva, Arestides Alves Lins, et al. · Current Medicinal Chemistry · 15
Targeting SmCB1: Perspectives and Insights to Design Antischistosomal Drugs
2023 · Igor José dos Santos Nascimento, Sonaly Lima Albino, et al. · Current Medicinal Chemistry · 14
Potentiating‐antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi‐drug resistant (MDR) strains
2023 · Ana Carolina Justino de Araújo, Priscilla Ramos Freitas, et al. · Fundamental and Clinical Pharmacology · 14
Works count: 88
Citation count: 1,060
H-index: 20
I10-index: 31
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