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Xuankuo Xu
Institutions:
Bristol-Myers Squibb (United States),
AstraZeneca (United States)
Observed institutions:
Bristol-Myers Squibb (United States),
AstraZeneca (United States),
University of Delaware
ORCID:
0000-0002-5557-0284
Observed ORCID:
0000-0002-5557-0284
OpenAlex ID:
A5045339754
Biomanufacturing evolution from conventional to intensified processes for productivity improvement: a case study
2020
·
Jianlin Xu
, Xuankuo Xu
, et al.
·
mAbs
·
95
PDF
Protein aggregation and mitigation strategy in low pH viral inactivation for monoclonal antibody purification
2019
·
Weixin Jin
, Zizhuo Xing
, et al.
·
mAbs
·
61
PDF
Improving titer while maintaining quality of final formulated drug substance via optimization of CHO cell culture conditions in low-iron chemically defined media
2018
·
Jianlin Xu
, Matthew S. Rehmann
, et al.
·
mAbs
·
60
PDF
Understanding mAb aggregation during low pH viral inactivation and subsequent neutralization
2019
·
Ruben Wälchli
, Mariana Ressurreição
, et al.
·
Biotechnology and Bioengineering
·
59
Emerging biomaterials for downstream manufacturing of therapeutic proteins
2019
·
Yi Li
, David Stern
, et al.
·
Acta Biomaterialia
·
58
Contributions of depth filter components to protein adsorption in bioprocessing
2018
·
Ohnmar Khanal
, Nripen Singh
, et al.
·
Biotechnology and Bioengineering
·
51
Model assisted comparison of Protein A resins and multi-column chromatography for capture processes
2018
·
Daniel Baur
, James M. Angelo
, et al.
·
Journal of Biotechnology
·
49
A Predictive Approach to Correlating Protein Adsorption Isotherms on Ion-Exchange Media
2008
·
Xuankuo Xu
, Abraham M. Lenhoff
·
The Journal of Physical Chemistry B
·
47
Brown drug substance color investigation in cell culture manufacturing using chemically defined media: A case study
2013
·
Jianlin Xu
, Mi Jin
, et al.
·
Process Biochemistry
·
37
Model‐assisted process characterization and validation for a continuous two‐column protein A capture process
2018
·
Daniel Baur
, James Angelo
, et al.
·
Biotechnology and Bioengineering
·
35
Chromatography of proteins on charge-variant ion exchangers and implications for optimizing protein uptake rates
2007
·
John F. Langford
, Xuankuo Xu
, et al.
·
Journal of Chromatography A
·
32
One‐step affinity capture and precipitation for improved purification of an industrial monoclonal antibody using Z‐ELP functionalized nanocages
2017
·
Andrew R. Swartz
, Xuankuo Xu
, et al.
·
Biotechnology and Bioengineering
·
31
Binary adsorption of globular proteins on ion-exchange media
2009
·
Xuankuo Xu
, Abraham M. Lenhoff
·
Journal of Chromatography A
·
29
Model based strategies towards protein A resin lifetime optimization and supervision
2020
·
Fabian Feidl
, Martin F. Luna
, et al.
·
Journal of Chromatography A
·
26
DNA retention on depth filters
2018
·
Ohnmar Khanal
, Xuankuo Xu
, et al.
·
Journal of Membrane Science
·
26
Selective Capture and Recovery of Monoclonal Antibodies by Self-Assembling Supramolecular Polymers of High Affinity for Protein Binding
2020
·
Yi Li
, Lye Lin Lock
, et al.
·
Nano Letters
·
25
Experimental Design of the Multicolumn Countercurrent Solvent Gradient Purification (MCSGP) Unit for the Separation of PEGylated Proteins
2021
·
Tae Keun Kim
, Chiara Botti
, et al.
·
Industrial & Engineering Chemistry Research
·
24
PDF
Predictive mechanistic modeling of loading and elution in protein A chromatography
2023
·
Soumitra Bhoyar
, Vijesh Kumar
, et al.
·
Journal of Chromatography A
·
21
Behavior of host-cell-protein-rich aggregates in antibody capture and polishing chromatography
2023
·
Chase E. Herman
, Lie Min
, et al.
·
Journal of Chromatography A
·
21
PDF
Analytical characterization of host‐cell‐protein‐rich aggregates in monoclonal antibody solutions
2023
·
Chase E. Herman
, Lie Min
, et al.
·
Biotechnology Progress
·
20
PDF
Bioinspired supramolecular engineering of self-assembling immunofibers for high affinity binding of immunoglobulin G
2018
·
Yi Li
, Lye Lin Lock
, et al.
·
Biomaterials
·
20
PDF
Conformation Preservation of α-Helical Peptides within Supramolecular Filamentous Assemblies
2017
·
Yi Li
, Yuzhu Wang
, et al.
·
Biomacromolecules
·
19
Shrinking-core modeling of binary chromatographic breakthrough
2011
·
Steven J. Traylor
, Xuankuo Xu
, et al.
·
Journal of Chromatography A
·
19
Physiochemical properties of enveloped viruses and arginine dictate inactivation
2021
·
Christa L. Meingast
, Pratik U. Joshi
, et al.
·
Biotechnology Journal
·
17
High‐efficiency affinity precipitation of multiple industrial mAbs and Fc‐fusion proteins from cell culture harvests using Z‐ELP‐E2 nanocages
2018
·
Andrew R. Swartz
, Xuankuo Xu
, et al.
·
Biotechnology and Bioengineering
·
17
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Works count:
68
Citation count:
1,136
H-index:
20
I10-index:
37
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