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Osne F. Kirzner
Observed names:
O F Kirzner,
O Kirzner,
Osne F Kirzner,
Osne Kirzner,
osne kirzner
Institution:
Amsterdam University Medical Centers
Observed institutions:
Amsterdam UMC Location University of Amsterdam,
Netherlands Heart Institute,
Amsterdam University Medical Centers,
Amsterdam Cardiovascular Sciences,
University of Amsterdam
OpenAlex ID:
A5045439481
SCN10A-short gene therapy to restore conduction and protect against malignant cardiac arrhythmias
2025
·
Jianan Wang
, Arie O Verkerk
, et al.
·
European Heart Journal
·
19
AAV6 vectors provide superior gene transfer compared to AAV9 vectors following intramyocardial administration
2025
·
Jianan Wang
, Timo Jonker
, et al.
·
Molecular Therapy — Methods & Clinical Development
·
7
AAV6-mediated gene transfer of HCN1-ddd generates slightly faster baseline beating rates as compared to Hcn2 yet with a potential risk for pro-arrhythmia
2023
·
A Cervera Barea
, J Wang
, et al.
·
European Heart Journal
·
1
PDF
AAV-mediated long-term TBX18 expression causes cardiac fibrosis and fails to induce pacemaker activity in rodents
2026
·
Jianan Wang
, Mathilde R. Rivaud
, et al.
·
Journal of Clinical Investigation
PDF
Engineering of bidirectional cardiomyocyte-specific promoters to independently express two transgenes in AAV gene therapy
2026
·
R N Visser
, T Jonker
, et al.
·
European Journal of Heart Failure
AAV6-HCN4t-mediated biological pacing in rodent and porcine models of complete AV block
2026
·
Evelien Birza
, Jianan Wang
, et al.
·
Journal of Molecular and Cellular Cardiology Plus
Adeno-associated virus (AAV)-TBX18 does not generate biological pacemaker activity, unlike AAV-Hcn2
2025
·
Jianan Wang
, Mathilde R. Rivaud
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
AAV6-HCN4t-mediated biological pacing as a potential life-saving therapy for congenital complete heart block
2025
·
Jianan Wang
, Evelien E. Birza
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Bs-499652-005 Aav-hcn4t-mediated Biological Pacing as a Potential Life-saving Therapy for Congenital Complete Heart Block
2025
·
Jianan Wang
, Evelien Birza
, et al.
·
Heart Rhythm
PDF
Po-05-203 Aav6-mediated Gene Transfer of Hcn1-δδδ Generates More Potent Pacing Than Hcn2 yet With a Potential Risk for Pro-arrhythmia
2024
·
Aina Cervera i Barea
, Jianan Wang
, et al.
·
Heart Rhythm
PDF
Po-05-204 Long-term Tbx18 Overexpression at Non-cytotoxic Levels Induces Abnormal Automaticity by Destabilizing Resting Membrane Potential
2024
·
Jianan Wang
, Mathilde Rivaud
, et al.
·
Heart Rhythm
HCN2-based biological pacing in a modified rat AV-block model
2024
·
T Jonker
, K Park
, et al.
·
Cardiovascular Research
PDF
Po-02-242 Aav6-ctnt-hcn2/skm1 Gene Transfer Enables a Transient Biological Pacemaker Activity in a Porcine Model of Cavb
2023
·
Aina Cervera i Barea
, Jianan Wang
, et al.
·
Heart Rhythm
PDF
Po-02-244 Aav6-mediated Gfp Gene Transfer Induces Tachyarrhythmias in a Porcine Model of Av Block
2023
·
Aina Cervera i Barea
, Jianan Wang
, et al.
·
Heart Rhythm
PDF
Bs-514-02 Transient Biological Pacing Based on Aav6-hcn2/skm1 Gene Transfer in Pigs With Complete Heart Block
2022
·
Aina Cervera i Barea
, Jianan Wang
, et al.
·
Heart Rhythm
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Works count:
15
Citation count:
27
H-index:
2
I10-index:
1
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