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Lucas Villas Bôas Hoelz

Observed names: Hoelz, Lucas V.B., Hoelz, Lucas Villas Boas, Hoelz, Lucas Villas Bôas, L. V. B. Hoelz, L.V.B. Hoelz, Lucas Hoelz, Lucas V. B. Hoelz, Lucas V.B. Hoelz, Lucas VB Hoelz, Lucas Villas Boas Hoelz, Lucas Villas-Boas Hoelz
Observed institutions: Universidade Federal do Rio de Janeiro, Universidade Federal Fluminense, Instituto Federal do Rio de Janeiro, Instituto de Biofísica Carlos Chagas Filho, Instituto Oswaldo Cruz, Instituto de Tecnologia em Fármacos, Fundação Oswaldo Cruz
ORCID: 0000-0001-5592-3089
Observed ORCID: 0000-0001-5592-3089
OpenAlex ID: A5045550967
The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication
2017 · Carolina Q. Sacramento, Gabrielle R. de Melo, et al. · Scientific Reports · 250
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Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo
2019 · Caroline S. de Freitas, Luiza M. Higa, et al. · PLoS neglected tropical diseases · 125
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In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19
2021 · Carolina Q Sacramento, Natalia Fintelman-Rodrigues, et al. · Journal of Antimicrobial Chemotherapy · 119
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Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication
2018 · André C. Ferreira, Patrícia A. Reis, et al. · Antimicrobial Agents and Chemotherapy · 107
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Evaluation of 7-arylaminopyrazolo[1,5-a]pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors
2016 · Luís Felipe S.P. Azeredo, Julia P. Coutinho, et al. · European Journal of Medicinal Chemistry · 85
Pyrroles as Privileged Scaffolds in the Search for New Potential HIV Inhibitors
2021 · Maria da Conceição Avelino Dias Bianco, Debora Inacio Leite Firmino Marinho, et al. · Pharmaceuticals · 63
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Plasmodium Falciparum Dihydroorotate Dehydrogenase: A Drug Target against Malaria
2018 · Lucas VB Hoelz, Felipe A Calil, et al. · Future Medicinal Chemistry · 60
Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors
2020 · Flávia F. Silveira, Juliana O. de Souza, et al. · European Journal of Medicinal Chemistry · 48
Structural and Functional Analysis of a Platelet-Activating Lysophosphatidylcholine of Trypanosoma cruzi
2014 · Felipe Gazos-Lopes, Mauricio M. Oliveira, et al. · PLoS neglected tropical diseases · 37
Receptor-dependent (RD) 3D-QSAR approach of a series of benzylpiperidine inhibitors of human acetylcholinesterase (HuAChE)
2010 · Jocley Queiroz Araújo, Monique Araújo de Brito, et al. · European Journal of Medicinal Chemistry · 30
New pyrazolopyrimidine derivatives as Leishmania amazonensis arginase inhibitors
2019 · Livia M. Feitosa, Edson R. da Silva, et al. · Bioorganic & Medicinal Chemistry · 24
Quantitative structure-activity relationships of antioxidant phenolic compounds.
2010 · Lucas Villas Bôas Hoelz, Bruno A. C. Horta, et al. · Journal of chemical and pharmaceutical research · 24
New 1,2,3‐triazole‐based analogues of benznidazole for use against Trypanosoma cruzi infection: In vitro and in vivo evaluations
2018 · Débora Inácio Leite, Fábio de Vasconcellos Fontes, et al. · Chemical Biology & Drug Design · 22
Ponatinib: A Review of the History of Medicinal Chemistry behind Its Development
2024 · Mayara Nascimento, Stefany Moura, et al. · Pharmaceuticals · 21
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P2X7 receptor inhibition by 2-amino-3-aryl-1,4-naphthoquinones
2020 · Daniela de Luna Martins, Adriel Alves Borges, et al. · Bioorganic Chemistry · 21
Synthesis of benzoylthiourea derivatives and analysis of their antibacterial performance against planktonic Staphylococcus aureus and its biofilms
2020 · L.C.S. Pinheiro, L.V.B. Hoelz, et al. · Letters in Applied Microbiology · 19
Molecular dynamics simulations of the free and inhibitor-bound cruzain systems in aqueous solvent: insights on the inhibition mechanism in acidic pH
2015 · L.V.B. Hoelz, V.F. Leal, et al. · Journal of Biomolecular Structure and Dynamics · 18
A Selective Adenylyl Cyclase 1 Inhibitor Relieves Pain Without Causing Tolerance
2022 · Gianna Giacoletti, Tatum Price, et al. · Frontiers in Pharmacology · 17
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Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors
2019 · Daniel T. G. Gonzaga, Felipe H. Oliveira, et al. · Frontiers in Chemistry · 17
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Antileishmanial Chemotherapy: A Literature Review
2016 · Mônica Macedo Bastos, Lucas Villas Bôas Hoelz, et al. · Revista Virtual de Química · 17
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Imatinib derivatives as inhibitors of K562 cells in chronic myeloid leukemia
2017 · Liviane D. Azevedo, Mônica M. Bastos, et al. · Medicinal Chemistry Research · 16
Kinetic resolution of (±)-1,2-O-isopropylidene-3,6-di-O-benzyl-myo-inositol by lipases: An experimental and theoretical study on the reaction of a key precursor of chiral inositols
2011 · Alessandro Bolis Costa Simas, Angelo Amaro Theodoro da Silva, et al. · Journal of Molecular Catalysis B Enzymatic · 15
Phenylamino-pyrimidine (PAP) Privileged Structure: Synthesis and Medicinal Applications
2020 · Luiz Claudio Ferreira Pimentel, Anna Claudia Cunha, et al. · Current Topics in Medicinal Chemistry · 13
Synthesis, biological evaluation and molecular modeling of pseudo-peptides based statine as inhibitors for human tissue kallikrein 5
2016 · Lucas V.B. Hoelz, Bruna C. Zorzanelli, et al. · European Journal of Medicinal Chemistry · 11
Solvent Free, Microwave Assisted Conversion of Aldehydes into Nitriles and Oximes in the Presence of NH2OH·HCl and TiO2
2009 · Lucas Villas-Boas Hoelz, Biank Tomaz Gonçalves, et al. · Molecules · 11
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Works count: 54
Citation count: 1,281
H-index: 17
I10-index: 28
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