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Younghoon Jang
Observed names:
Y H Jang,
Young Hoon Jang
Institutions:
National Institutes of Health,
Changwon National University,
National Institute of Diabetes and Digestive and Kidney Diseases
Observed institutions:
National Institutes of Health,
Changwon National University,
National Institute of Diabetes and Digestive and Kidney Diseases,
Samsung Biomedical Research Institute,
Pusan National University,
Sungkyunkwan University
show all 6
ORCID:
0000-0002-5705-4945
Observed ORCID:
0000-0002-5705-4945
OpenAlex ID:
A5045670192
Histone H3 lysine 4 methyltransferase KMT2D
2017
·
Eugene Froimchuk
, Younghoon Jang
, et al.
·
Gene
·
307
Somatic Mutations Increase Hepatic Clonal Fitness and Regeneration in Chronic Liver Disease
2019
·
Min Zhu
, Tianshi Lu
, et al.
·
Cell
·
244
PDF
Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis
2017
·
Ji-Eun Lee
, Young-Kwon Park
, et al.
·
Nature Communications
·
209
PDF
MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis
2017
·
Binbin Lai
, Ji-Eun Lee
, et al.
·
Nucleic Acids Research
·
188
HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis
2018
·
Yuqing Sun
, Bo Zhou
, et al.
·
Cancer Cell
·
160
PDF
H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development
2018
·
Younghoon Jang
, Aaron Broun
, et al.
·
Nucleic Acids Research
·
147
MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping
2017
·
Katarzyna Placek
, Gangqing Hu
, et al.
·
Nature Immunology
·
95
Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function
2018
·
Lenan Zhuang
, Younghoon Jang
, et al.
·
Nature Communications
·
82
PDF
MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner
2023
·
Guojia Xie
, Ji-Eun Lee
, et al.
·
Nature Genetics
·
73
PDF
H3K4 Methyltransferase Activity Is Required for MLL4 Protein Stability
2016
·
Younghoon Jang
, Chaochen Wang
, et al.
·
Journal of Molecular Biology
·
63
Metabolic Effects of Ketogenic Diets: Exploring Whole-Body Metabolism in Connection with Adipose Tissue and Other Metabolic Organs
2024
·
Yusra Ahmad
, Dong Soo Seo
, et al.
·
International Journal of Molecular Sciences
·
59
PDF
Cathepsin D as a potential therapeutic target to enhance anticancer drug-induced apoptosis via RNF183-mediated destabilization of Bcl-xL in cancer cells
2022
·
Seung Un Seo
, Seon Min Woo
, et al.
·
Cell Death and Disease
·
57
PDF
Prognostic significance and function of phosphorylated ribosomal protein S6 in esophageal squamous cell carcinoma
2012
·
Seok-Hyung Kim
, Young Hoon Jang
, et al.
·
Modern Pathology
·
56
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF
2019
·
Yi Zhang
, Younghoon Jang
, et al.
·
Nature Communications
·
53
Phospholipase D-mediated autophagic regulation is a potential target for cancer therapy
2013
·
Y H Jang
, K Y Choi
, et al.
·
Cell Death and Differentiation
·
53
Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells
2009
·
Dong Woo Kang
, Ji Young Lee
, et al.
·
Experimental & Molecular Medicine
·
53
PDF
N-Formyl-Methionyl-Leucyl-Phenylalanine (fMLP) Promotes Osteoblast Differentiation via the N-Formyl Peptide Receptor 1-mediated Signaling Pathway in Human Mesenchymal Stem Cells from Bone Marrow
2011
·
Min Kyoung Shin
, Young Hoon Jang
, et al.
·
Journal of Biological Chemistry
·
42
Assessment on acute and multigenerational toxicity of 1,3-diphenylguanidine (DPG) on freshwater water fleas (Moina macrocopa): Developmental, reproductive and oxidative stress effects
2024
·
Suman Thodhal Yoganandham
, Soo-Yeon Kim
, et al.
·
Environmental Chemistry and Ecotoxicology
·
24
Cleavage of phospholipase D1 by caspase promotes apoptosis via modulation of the p53-dependent cell death pathway
2008
·
Y H Jang
, S Namkoong
, et al.
·
Cell Death and Differentiation
·
24
Phospholipase D1 is upregulated by vorinostat and confers resistance to vorinostat in glioblastoma
2020
·
Dong Woo Kang
, Won Chan Hwang
, et al.
·
Journal of Cellular Physiology
·
23
PDF
MED1 is a lipogenesis coactivator required for postnatal adipose expansion
2021
·
Younghoon Jang
, Young-Kwon Park
, et al.
·
Genes & Development
·
22
PDF
Differential regulation of apoptosis by caspase-mediated cleavage of phospholipase D isozymes
2008
·
Young Hoon Jang
, Bong-Hyun Ahn
, et al.
·
Cellular Signalling
·
21
Clinicopathologic significance and function of mammalian target of rapamycin activation in esophageal squamous cell carcinoma
2012
·
Seok-Hyung Kim
, Gia Cac Chau
, et al.
·
Human Pathology
·
17
Nuclear Localization of Phospholipase D1 Mediates the Activation of Nuclear Protein Kinase Cα and Extracellular Signal-regulated Kinase Signaling Pathways
2010
·
Young Hoon Jang
, Do Sik Min
·
Journal of Biological Chemistry
·
17
Inhibition of phospholipase D2 augments histone deacetylase inhibitor-induced cell death in breast cancer cells
2020
·
Won Chan Hwang
, Dong Woo Kang
, et al.
·
Biological Research
·
12
PDF
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Works count:
43
Citation count:
2,167
H-index:
21
I10-index:
27
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