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Julie A. Spicer

Structure−Activity Relationships for Substituted Bis(acridine-4-carboxamides): A New Class of Anticancer Agents
1999 · Swarna A. Gamage, Julie A. Spicer, et al. · Journal of Medicinal Chemistry · 170
Structure−Activity Relationships for Pyrido-, Imidazo-, Pyrazolo-, Pyrazino-, and Pyrrolophenazinecarboxamides as Topoisomerase-Targeted Anticancer Agents
2002 · Swarna A. Gamage, Julie A. Spicer, et al. · Journal of Medicinal Chemistry · 150
Bis(phenazine-1-carboxamides): Structure−Activity Relationships for a New Class of Dual Topoisomerase I/II-Directed Anticancer Drugs
2000 · Julie A. Spicer, Swarna A. Gamage, et al. · Journal of Medicinal Chemistry · 109
Activation of a PAK-MEK signalling pathway in malaria parasite-infected erythrocytes
2011 · Audrey Sicard, Jean-Philippe Semblat, et al. · Cellular Microbiology · 90
A Selective and Slowly Reversible Inhibitor of l -Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells
2016 · Kristiina M. Huttunen, Mikko Gynther, et al. · Journal of Medicinal Chemistry · 71
Structure−Activity Relationships for Acridine-Substituted Analogues of the Mixed Topoisomerase I/II InhibitorN-[2-(Dimethylamino)ethyl]acridine-4-carboxamide
1997 · Julie A. Spicer, Swarna A. Gamage, et al. · Journal of Medicinal Chemistry · 69
Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family
2016 · Jeff B. Smaill, Andrea J. Gonzales, et al. · Journal of Medicinal Chemistry · 66
Identification of Conjugated Triene Oxidation Products of .alpha.-Farnesene in Apple Skin
1995 · Daryl D. Rowan, John M. Allen, et al. · Journal of Agricultural and Food Chemistry · 64
Dicationic Bis(9-methylphenazine-1-carboxamides): Relationships between Biological Activity and Linker Chain Structure for a Series of Potent Topoisomerase Targeted Anticancer Drugs
2001 · Swarna A. Gamage, Julie A. Spicer, et al. · Journal of Medicinal Chemistry · 61
4-Anilino-5-carboxamido-2-pyridone Derivatives as Noncompetitive Inhibitors of Mitogen-Activated Protein Kinase Kinase
2007 · Julie A. Spicer, Gordon W. Rewcastle, et al. · Journal of Medicinal Chemistry · 52
l -Type amino acid transporter 1 (lat1)-mediated targeted delivery of perforin inhibitors
2015 · Kristiina M. Huttunen, Johanna Huttunen, et al. · International Journal of Pharmaceutics · 44
Perforin inhibition protects from lethal endothelial damage during fulminant viral hepatitis
2018 · M. Welz, S. Eickhoff, et al. · Nature Communications · 41
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IFN-γ+ cytotoxic CD4+ T lymphocytes are involved in the pathogenesis of colitis induced by IL-23 and the food colorant Red 40
2022 · Lili Chen, Zhengxiang He, et al. · Cellular and Molecular Immunology · 39
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Systemic and Brain Pharmacokinetics of Perforin Inhibitor Prodrugs
2016 · Mikko Gynther, Darryl S. Pickering, et al. · Molecular Pharmaceutics · 39
Dihydrofuro[3,4-c]pyridinones as Inhibitors of the Cytolytic Effects of the Pore-Forming Glycoprotein Perforin
2008 · Gersande Lena, Joseph A. Trapani, et al. · Journal of Medicinal Chemistry · 36
Exploration of a Series of 5-Arylidene-2-thioxoimidazolidin-4-ones as Inhibitors of the Cytolytic Protein Perforin
2013 · Julie A. Spicer, Gersande Lena, et al. · Journal of Medicinal Chemistry · 34
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Inhibition of the cellular function of perforin by 1-amino-2,4-dicyanopyrido[1,2-a]benzimidazoles
2011 · Dani M. Lyons, Kristiina M. Huttunen, et al. · Bioorganic & Medicinal Chemistry · 30
Advancements in oral insulin: A century of research and the emergence of targeted nanoparticle strategies
2024 · Yue Han, Julie Spicer, et al. · European Journal of Lipid Science and Technology · 28
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Effects of a Small-Molecule Perforin Inhibitor in a Mouse Model of CD8 T Cell–Mediated Neuroinflammation
2023 · Carmen Gonzalez-Fierro, Coralie Fonte, et al. · Neurology Neuroimmunology & Neuroinflammation · 24
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Synthesis and evaluation of unsymmetrical bis(arylcarboxamides) designed as topoisomerase-Targeted anticancer drugs
2002 · Julie A Spicer, Swarna A Gamage, et al. · Bioorganic & Medicinal Chemistry · 23
A new synthesis of substituted acridine-4-carboxylic acids and the anticancer drug N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA)
1997 · Swarna A. Gamage, Julie A. Spicer, et al. · Tetrahedron Letters · 21
Diarylthiophenes as inhibitors of the pore-forming protein perforin
2015 · Christian K. Miller, Kristiina M. Huttunen, et al. · Bioorganic & Medicinal Chemistry Letters · 19
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Inhibition of the pore-forming protein perforin by a series of aryl-substituted isobenzofuran-1(3H)-ones
2011 · Julie A. Spicer, Kristiina M. Huttunen, et al. · Bioorganic & Medicinal Chemistry · 19
Benzenesulphonamide inhibitors of the cytolytic protein perforin
2016 · Julie A. Spicer, Christian K. Miller, et al. · Bioorganic & Medicinal Chemistry Letters · 18
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Dimeric analogues of non-cationic tricyclic aromatic carboxamides are a new class of cytotoxic agents.
1999 · J A Spicer, S A Gamage, et al. · PubMed · 18
Works count: 53
Citation count: 1,454
H-index: 21
I10-index: 30
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