Get started
Author

Goichi Honda

Large-scale identification and characterization of human genes that activate NF-κB and MAPK signaling pathways
2003 · Akio Matsuda, Yutaka Suzuki, et al. · Oncogene · 400
Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation.
1987 · K. Suzuki, H. Kusumoto, et al. · The EMBO Journal · 367
PDF
An atherogenic stimulus homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells
1992 · T Hayashi, G Honda, et al. · Blood · 163
PDF
Antithrombotic effect of recombinant human thrombomodulin on thrombin- induced thromboembolism in mice
1990 · K Gomi, M Zushi, et al. · Blood · 142
PDF
A domain Composed of Epidermal Growth Factor-like Structures of Human Thrombomodulin Is Essential for Thrombin Binding and for Protein C Activation
1989 · K Suzuki, T Hayashi, et al. · Journal of Biological Chemistry · 111
Thrombomodulin Protects Endothelial Cells From a Calcineurin Inhibitor–Induced Cytotoxicity by Upregulation of Extracellular Signal–Regulated Kinase/Myeloid Leukemia Cell-1 Signaling
2012 · Takayuki Ikezoe, Jing Yang, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 59
Thrombomodulin alfa treatment in patients with acute promyelocytic leukemia and disseminated intravascular coagulation: A retrospective analysis of an open-label, multicenter, post-marketing surveillance study cohort
2014 · Tadashi Matsushita, Jyunichi Watanabe, et al. · Thrombosis Research · 47
Aspartic acid 349 in the fourth epidermal growth factor-like structure of human thrombomodulin plays a role in its Ca(2+)-mediated binding to protein C.
1991 · M. Zushi, K. Gomi, et al. · Journal of Biological Chemistry · 45
Post-marketing surveillance of thrombomodulin alfa, a novel treatment of disseminated intravascular coagulation - Safety and efficacy in 1,032 patients with hematologic malignancy
2014 · Hidesaku Asakura, Hoyu Takahashi, et al. · Thrombosis Research · 37
The fifth epidermal growth factor-like region of thrombomodulin exerts cytoprotective function and prevents SOS in a murine model
2016 · T Ikezoe, J Yang, et al. · Bone Marrow Transplantation · 31
G-protein coupled receptor 15 mediates angiogenesis and cytoprotective function of thrombomodulin
2017 · Bin Pan, Xiangmin Wang, et al. · Scientific Reports · 30
PDF
The fifth epidermal growth factor like region of thrombomodulin alleviates LPS-induced sepsis through interacting with GPR15
2017 · Bin Pan, Xiangmin Wang, et al. · Thrombosis and Haemostasis · 28
A case of thrombomodulin mutation causing defective thrombin binding with absence of protein C and TAFI activation
2020 · Masahiko Okada, Norio Tominaga, et al. · Blood Advances · 27
PDF
The Fifth Epidermal Growth Factor–like Region of Thrombomodulin Alleviates Murine Graft-versus-Host Disease in a G-Protein Coupled Receptor 15 Dependent Manner
2017 · Bin Pan, Xiangmin Wang, et al. · Transplantation and Cellular Therapy · 25
Recombinant soluble human thrombomodulin (thrombomodulin alfa) in the treatment of neonatal disseminated intravascular coagulation
2013 · Akira Shirahata, Jun Mimuro, et al. · European Journal of Pediatrics · 25
Thrombomodulin enhances the antifibrinolytic and antileukemic effects of all–trans retinoic acid in acute promyelocytic leukemia cells
2012 · Takayuki Ikezoe, Jing Yang, et al. · Experimental Hematology · 23
PDF
An evaluation of the Japanese Society on Thrombosis and Hemostasis criteria for disseminated intravascular coagulation as a predictor of prognosis in patients with infection
2021 · Seiji Madoiwa, Goichi Honda, et al. · International Journal of Laboratory Hematology · 21
LFA-1 and Mac-1 integrins bind to the serine/threonine-rich domain of thrombomodulin
2016 · Eiji Kawamoto, Takayuki Okamoto, et al. · Biochemical and Biophysical Research Communications · 20
PDF
Human soluble thrombomodulin-induced blockade of peripheral HMGB1-dependent allodynia in mice requires both the lectin-like and EGF-like domains
2017 · Yusuke Hayashi, Ryuichi Tsujita, et al. · Biochemical and Biophysical Research Communications · 18
Hypofibrinogenemia is associated with a high degree of risk in infectious diseases: a post-hoc analysis of post-marketing surveillance of patients with disseminated intravascular coagulation treated with thrombomodulin alfa
2021 · Kazuo Kawasugi, Hideo Wada, et al. · Thrombosis Journal · 15
PDF
Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain
2018 · Xiangmin Wang, Bin Pan, et al. · Haematologica · 15
Benefit Profile of Thrombomodulin Alfa Combined with Antithrombin Concentrate in Patients with Sepsis-Induced Disseminated Intravascular Coagulation
2022 · Atsushi Murao, Takayuki Kato, et al. · Clinical and Applied Thrombosis/Hemostasis · 14
Sepsis-Associated DIC with Decreased Levels of Antithrombin and Fibrinogen is the Target for Combination Therapy with Thrombomodulin Alfa and Antithrombin
2023 · Hideo Wada, Kazuo Kawasugi, et al. · TH Open · 13
PDF
Surveillance of the safety and efficacy of recombinant human soluble thrombomodulin in patients with obstetrical disseminated intravascular coagulation
2017 · Takao Kobayashi, Masahiro Kajiki, et al. · Thrombosis Research · 13
Postmarketing Surveillance of Recombinant Human Soluble Thrombomodulin (Thrombomodulin α) in Pediatric Patients With Disseminated Intravascular Coagulation
2014 · Akira Shirahata, Jun Mimuro, et al. · Clinical and Applied Thrombosis/Hemostasis · 12
Works count: 63
Citation count: 1,777
H-index: 18
I10-index: 28
Year
Topic
Type