Author

Joan C. Krepinsky

Observed names: J KREPINSKY, J. C. Krepinsky, J. KREPINSKY, Joan C Krepinsky, Joan Krepinsky, Joan C. Krepinsky, Krepinsky, Joan, Krepinsky, Joan C.

Institution: McMaster University

Observed institutions: Western University, Dalhousie University, University of Toronto, St. Joseph’s Healthcare Hamilton, The University of Texas Southwestern Medical Center, McMaster University

ORCID: 0000-0002-6761-909X

Observed ORCID: 0000-0002-6761-909X

OpenAlex ID: A5046438155

RhoA/Rho-Kinase Contribute to the Pathogenesis of Diabetic Renal Disease

2008 · Fangfang Peng, Dongcheng Wu, et al. · Diabetes · 184

Prolonged sulfonylurea-induced hypoglycemia in diabetic patients with end-stage renal disease

2000 · Joan Krepinsky, Alistair J. Ingram, et al. · American Journal of Kidney Diseases · 114

PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells

2009 · Dongcheng Wu, Fangfang Peng, et al. · Journal of the American Society of Nephrology · 109

Caveolin-1 phosphorylation is required for stretch-induced EGFR and Akt activation in mesangial cells

2007 · B ZHANG, F PENG, et al. · Cellular Signalling · 108

High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells

2015 · Renzhong Li, Lalita Uttarwar, et al. · Journal of Biological Chemistry · 90

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Nitric Oxide Inhibits Stretch-Induced MAPK Activation in Mesangial Cells Through RhoA Inactivation

2003 · Joan C. Krepinsky, Alistair J. Ingram, et al. · Journal of the American Society of Nephrology · 77

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TGFβ-induced RhoA activation and fibronectin production in mesangial cells require caveolae

2008 · Fangfang Peng, Baifang Zhang, et al. · American Journal of Physiology-Renal Physiology · 72

Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression

2011 · Rohan Samarakoon, Subhanir S. Chitnis, et al. · PLoS ONE · 68

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Endoplasmic reticulum stress as a driver and therapeutic target for kidney disease

2025 · Jae Hyun Byun, Paul F. Lebeau, et al. · Nature Reviews Nephrology · 65

Endoplasmic Reticulum Stress and Renal Disease

2009 · Jeffrey G. Dickhout, Joan C. Krepinsky · Antioxidants and Redox Signaling · 62

Collagen I induction by high glucose levels is mediated by epidermal growth factor receptor and phosphoinositide 3-kinase/Akt signalling in mesangial cells

2007 · D. Wu, F. Peng, et al. · Diabetologia · 61

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RhoA Activation in Mesangial Cells by Mechanical Strain Depends on Caveolae and Caveolin-1 Interaction

2006 · Fangfang Peng, Dongcheng Wu, et al. · Journal of the American Society of Nephrology · 56

Mechanical Strain-Induced RhoA Activation Requires NADPH Oxidase-Mediated ROS Generation in Caveolae

2010 · Ying Zhang, Fangfang Peng, et al. · Antioxidants and Redox Signaling · 55

Akt Mediates Mechanical Strain-Induced Collagen Production by Mesangial Cells

2005 · Joan C. Krepinsky, Yanxia Li, et al. · Journal of the American Society of Nephrology · 53

Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions

2018 · Elizabeth D. Crane, Ali A. Al-Hashimi, et al. · JCI Insight · 51

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SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis

2014 · Tony N. Wang, Xing Chen, et al. · Journal of the American Society of Nephrology · 51

SREBP-1 activation by glucose mediates TGF-β upregulation in mesangial cells

2011 · Lalita Uttarwar, Bo Gao, et al. · American Journal of Physiology-Renal Physiology · 48

Endoplasmic reticulum stress inhibition attenuates hypertensive chronic kidney disease through reduction in proteinuria

2017 · Zahraa Mohammed-Ali, Chao Lu, et al. · Scientific Reports · 46

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Activation of mesangial cell MAPK in responseto homocysteine

2004 · Alistair J. Ingram, Joan C. Krepinsky, et al. · Kidney International · 46

Colchicine attenuates renal injury in a model of hypertensive chronic kidney disease

2013 · Tianxiu Guan, Bo Gao, et al. · American Journal of Physiology-Renal Physiology · 45

Follistatin Protects Against Glomerular Mesangial Cell Apoptosis and Oxidative Stress to Ameliorate Chronic Kidney Disease

2019 · Neel Mehta, Agata L. Gava, et al. · Antioxidants and Redox Signaling · 43

Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy

2019 · Richard Van Krieken, Neel Mehta, et al. · Journal of Biological Chemistry · 43

SREBP-1 is a novel mediator of TGFβ1 signaling in mesangial cells

2014 · Guang Chen, Tony Wang, et al. · Journal of Molecular Cell Biology · 43

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HB-EGF release mediates glucose-induced activation of the epidermal growth factor receptor in mesangial cells

2011 · L. Uttarwar, F. Peng, et al. · American Journal of Physiology-Renal Physiology · 42

Caveolin-1 in the Pathogenesis of Diabetic Nephropathy: Potential Therapeutic Target?

2017 · Richard Van Krieken, Joan C. Krepinsky · Current Diabetes Reports · 38

Works count: 109

Citation count: 2,403

H-index: 30

I10-index: 53