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Petra Břehová
Observed names:
Brehova, P.,
Břehová, P. (Petra),
Břehová, Petra,
Petra Brehova,
Petra Doláková,
Petra Doláková‡
show all 6
Institutions:
Czech Academy of Sciences,
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry
Observed institutions:
Czech Academy of Sciences,
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry
ORCID:
0000-0001-5353-889X
Observed ORCID:
0000-0001-5353-889X
OpenAlex ID:
A5046499559
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP)
2021
·
Markéta Pimková Polidarová
, Petra Břehová
, et al.
·
Journal of Medicinal Chemistry
·
44
Acyclic nucleoside bisphosphonates: Synthesis and properties of chiral 2-amino-4,6-bis[(phosphonomethoxy)alkoxy]pyrimidines
2008
·
Petra Doláková
, Martin Dračínský
, et al.
·
European Journal of Medicinal Chemistry
·
35
Synthesis of Ester Prodrugs of 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as Anti-Poxvirus Agents
2010
·
Marcela Krečmerová
, Antonín Holý
, et al.
·
Journal of Medicinal Chemistry
·
32
Synthetic Stimulator of Interferon Genes (STING) Agonists Induce a Cytokine-Mediated Anti-Hepatitis B Virus Response in Nonparenchymal Liver Cells
2022
·
Marketa Pimkova Polidarova
, Lenka Vanekova
, et al.
·
ACS Infectious Diseases
·
23
Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential
2022
·
Milan Dejmek
, Michal Šála
, et al.
·
Structure
·
19
STING Agonist-Mediated Cytokine Secretion Is Accompanied by Monocyte Apoptosis
2022
·
Marketa Pimkova Polidarova
, Petra Brehova
, et al.
·
ACS Infectious Diseases
·
18
Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction
2023
·
Gal Chaim Nuta
, Yuval Gilad
, et al.
·
Autophagy
·
17
PDF
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping
2023
·
Petra Břehová
, Eva Řezníčková
, et al.
·
Journal of Medicinal Chemistry
·
16
PDF
The efficient synthesis of 2-arylpyrimidine acyclic nucleoside phosphonates using Liebeskind–Srogl cross-coupling reaction
2011
·
Petra Břehová
, Michal Česnek
, et al.
·
Tetrahedron
·
15
Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases
2016
·
Petra Břehová
, Markéta Šmídková
, et al.
·
ChemMedChem
·
12
Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-1-yl)methyl]uracils through the “click” protocol
2011
·
Petr Jansa
, Petr Špaček
, et al.
·
Collection of Czechoslovak Chemical Communications
·
12
The separation of cyclic diadenosine diphosphorothioate and the diastereomers of its difluorinated derivative and the estimation of the binding constants and ionic mobilities of their complexes with 2‐hydroxypropyl‐β‐cyclodextrin by affinity capillary electrophoresis
2024
·
Sille Štěpánová
, Petra Břehová
, et al.
·
Electrophoresis
·
9
PDF
Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases
2021
·
Petra Břehová
, Ema Chaloupecká
, et al.
·
European Journal of Medicinal Chemistry
·
9
The preparation of 3H-labeled acyclic nucleoside phosphonates and study of their stability
2010
·
Tomáš Elbert
, Petra Břehová
, et al.
·
Collection of Czechoslovak Chemical Communications
·
9
Synthesis of Analogues of Acyclic Nucleoside Diphosphates Containing a (Phosphonomethyl)phosphanyl Moiety and Studies of Their Phosphorylation
2009
·
Petra Doláková
, Martin Dračínský
, et al.
·
European Journal of Organic Chemistry
·
9
Efficient Synthesis of Pyrimidinecarbonitriles and Their Derivatives
2007
·
Petra Doláková
, Milena Masojídková
, et al.
·
Heterocycles
·
8
The synthesis of the 8-C-substituted 2,6-diamino-9-[2-(phosphonomethoxy)ethyl]purine (PMEDAP) derivatives by diverse cross-coupling reactions
2011
·
Ondřej Sedláček
, Petra Břehová
, et al.
·
Canadian Journal of Chemistry
·
7
Synthesis of Base Substituted 2-Hydroxy-3-(purin-9-yl)-propanoic Acids and 4-(Purin-9-yl)-3-butenoic Acids
2003
·
Petra Doláková‡
, Milena Masojídková
, et al.
·
Nucleosides Nucleotides & Nucleic Acids
·
7
Structure–activity relationship study of small-molecule inhibitor of Atg12-Atg3 protein–protein interaction
2024
·
Krystof Skach
, Jiri Boserle
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
4
Acidity constants and protonation sites of cyclic dinucleotides determined by capillary electrophoresis, quantum chemical calculations, and NMR spectroscopy
2023
·
Sille Štěpánová
, Erik Andris
, et al.
·
Electrophoresis
·
4
PDF
Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus
2018
·
Ondřej Baszczyňski
, Martin Maxmilian Kaiser
, et al.
·
Antiviral chemistry & chemotherapy
·
4
PDF
Inhibition of human purine nucleoside phosphorylase by tenofovir phosphate congeners
2010
·
Ivan Votruba
, Jana Trýznová
, et al.
·
Collection of Czechoslovak Chemical Communications
·
3
Synthesis and immunobiological activity of base substituted 2-amino-3-(purin-9-yl)propanoic acid derivatives
2005
·
Petra Doláková
, Antonín Holý
, et al.
·
Bioorganic & Medicinal Chemistry
·
2
The efficient synthesis of 2-aryl substituted pyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling
2011
·
Michal Česnek
, Petra Břehová
, et al.
·
1
Acyclic purine and pyrimidine nucleotide analogs as ecto-5′-nucleotidase (CD73) inhibitors
2025
·
Stephanie Federico
, Christian Renn
, et al.
·
European Journal of Medicinal Chemistry
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Works count:
39
Citation count:
319
H-index:
11
I10-index:
11
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