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Jeff Smith
Observed names:
J Jeff Smith,
J. J. Smith,
J. Jeff Smith,
J. Jeff Smith,
Jeffery Smith
Institution:
Clatterbridge Cancer Centre NHS Foundation Trust
Observed institutions:
Queen Alexandra Hospital,
Clatterbridge Cancer Centre NHS Foundation Trust,
Bristol-Myers Squibb (United States),
Precision BioSciences (United States),
Liverpool University Hospitals NHS Foundation Trust,
Jounce Therapeutics (United States)
show all 6
ORCID:
0000-0002-0038-3748
Observed ORCID:
0000-0002-0038-3748
OpenAlex ID:
A5046587179
Integration of a CD19 CAR into the TCR Alpha Chain Locus Streamlines Production of Allogeneic Gene-Edited CAR T Cells
2017
·
Daniel T. MacLeod
, Jeyaraj Antony
, et al.
·
Molecular Therapy
·
277
PDF
Heritable targeted mutagenesis in maize using a designed endonuclease
2009
·
Huirong Gao
, Jeff Smith
, et al.
·
The Plant Journal
·
241
Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol
2018
·
Lili Wang
, Jeff Smith
, et al.
·
Nature Biotechnology
·
120
Mitochondrial targeted meganuclease as a platform to eliminate mutant mtDNA in vivo
2021
·
Ugne Zekonyte
, Sandra R. Bacman
, et al.
·
Nature Communications
·
94
PDF
Targeted DNA excision in Arabidopsis by a re-engineered homing endonuclease
2012
·
Mauricio S Antunes
, J Jeff Smith
, et al.
·
BMC Biotechnology
·
60
PDF
Targeting the hepatitis B cccDNA with a sequence-specific ARCUS nuclease to eliminate hepatitis B virus in vivo
2022
·
Cassandra L. Gorsuch
, Paige Nemec
, et al.
·
Molecular Therapy
·
54
PDF
Population Cellular Kinetics of Lisocabtagene Maraleucel, an Autologous CD19-Directed Chimeric Antigen Receptor T-Cell Product, in Patients with Relapsed/Refractory Large B-Cell Lymphoma
2021
·
Ken Ogasawara
, Michael Dodds
, et al.
·
Clinical Pharmacokinetics
·
51
PDF
Transient Expression of Virally Delivered Meganuclease In Planta Generates Inherited Genomic Deletions
2015
·
Arik Honig
, Ira Marton
, et al.
·
Molecular Plant
·
48
PDF
Efficient elimination of MELAS-associated m.3243G mutant mitochondrial DNA by an engineered mitoARCUS nuclease
2023
·
Wendy K. Shoop
, Janel Lape
, et al.
·
Nature Metabolism
·
46
PDF
In Vivo Cellular Expansion of Lisocabtagene Maraleucel and Association With Efficacy and Safety in Relapsed/Refractory Large B‐Cell Lymphoma
2022
·
Ken Ogasawara
, James Lymp
, et al.
·
Clinical Pharmacology & Therapeutics
·
39
PDF
Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors
2023
·
Ben Umiker
, Yasmin Hashambhoy-Ramsay
, et al.
·
Molecular Cancer Therapeutics
·
35
Management of secondary central nervous system lymphoma
2022
·
Kate Cwynarski
, Thomas Cummin
, et al.
·
British Journal of Haematology
·
26
Treatment-related outcomes and patterns of relapse in secondary CNS involvement by large B-cell lymphoma
2026
·
Juan Pablo Alderuccio
, Diva Baggio
, et al.
·
Blood
·
7
579. Meganucleases as an Efficient Tool for Genome Editing
2016
·
Victor V. Bartsevich
, John Morris
, et al.
·
Molecular Therapy
·
7
PDF
Cytoplasmic male sterility and abortive seed traits generated through mitochondrial genome editing coupled with allotopic expression of atp1 in tobacco
2023
·
Ralph E. Dewey
, Devarshi Selote
, et al.
·
Frontiers in Plant Science
·
6
Treating Transthyretin Amyloidosis via Adeno-Associated Virus Vector Delivery of Meganucleases
2022
·
Jenny A. Greig
, Camilo Breton
, et al.
·
Human Gene Therapy
·
6
High-efficiency homology-directed insertion into the genome using the engineered homing endonuclease ARCUS
2025
·
Laura Christian Resly
, Alan L Tubbs
, et al.
·
Nucleic Acids Research
·
5
PDF
T cell receptor knockout efficiency utilizing an engineered meganuclease is influenced by stimulation conditions.
2016
·
Audrey E Brown
, Daniel T MacLeod
, et al.
·
The Journal of Immunology
·
3
PBCAR19B, an Immune Evading Allogeneic CAR T Stealth Cell, Demonstrates Potent Anti-Tumor Responses and Prolonged B Cell Depletion Supporting Sustained Immune Evasion in Patients with Relapsed/Refractory (R/R) B-Cell Lymphoma (NHL)
2024
·
Usama Gergis
, Aaron Martin
, et al.
·
Blood
·
2
LBP-022 Preclinical safety data for PBGENE-HBV gene editing program supports advancement to clinical trials as a potentially curative treatment for chronic hepatitis B
2024
·
Emily Harrison
, Keely Dulmage
, et al.
·
Journal of Hepatology
·
2
Rho 1-2 meganuclease, an allele-specific gene-editing therapy, rejuvenates rod photoreceptor structure and function in a pig model of autosomal dominant Retinitis Pigmentosa (adRP).
2021
·
Archana Jalligampala
, Jennifer Noel
, et al.
·
Investigative Ophthalmology & Visual Science
·
2
217 Evaluating biomarkers of JTX-8064 (anti-LILRB2/ILT4 monoclonal antibody) in an ex vivo human tumor histoculture system to inform clinical development
2020
·
Yasmin Hashambhoy-Ramsay
, Vikki Spaulding
, et al.
·
Regular and Young Investigator Award Abstracts
·
2
LBP-043 First evidence of elimination and inactivation of cccDNA in liver biopsies collected from patients with chronic hepatitis B treated with PBGENE-HBV
2026
·
Man-Fung Yuen
, Alina Jucov
, et al.
·
Journal of Hepatology
·
1
RHO1-2 meganuclease gene editing targets human P23H rhodopsin-induced retinitis pigmentosa to rejuvenate rods and maintain cones
2025
·
Archana Jalligampala
, Jacob M. Young
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
PDF
200. Generation of CAR-T Cells Lacking T Cell Receptor and Human Leukocyte Antigen Using Engineered Meganucleases
2016
·
Christina Pham
, Aaron Martin
, et al.
·
Molecular Therapy
·
1
PDF
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Works count:
90
Citation count:
1,137
H-index:
12
I10-index:
12
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