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Leonardo Giovannoni

Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer.
2003 · Monica Santimaria, Giovanni Moscatelli, et al. · PubMed · 293
Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis.
1999 · F Viti, L Tarli, et al. · PubMed · 206
The tumour-targeting human L19-IL2 immunocytokine: Preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced renal cell carcinoma
2010 · Manfred Johannsen, Gianluca Spitaleri, et al. · European Journal of Cancer · 186
Intralesional administration of L19-IL2/L19-TNF in stage III or stage IVM1a melanoma patients: results of a phase II study
2015 · Riccardo Danielli, Roberto Patuzzo, et al. · Cancer Immunology Immunotherapy · 180
Expression of the oncofetal ED-B–containing fibronectin isoform in hematologic tumors enables ED-B–targeted 131I-L19SIP radioimmunotherapy in Hodgkin lymphoma patients
2009 · Stefanie Sauer, Paola A. Erba, et al. · Blood · 174
A Dose-Escalation and Signal-Generating Study of the Immunocytokine L19-IL2 in Combination with Dacarbazine for the Therapy of Patients with Metastatic Melanoma
2011 · Thomas K. Eigentler, Benjamin Weide, et al. · Clinical Cancer Research · 147
Antibody-Mediated Delivery of Interleukin-2 to the Stroma of Breast Cancer Strongly Enhances the Potency of Chemotherapy
2008 · Jessica Mårlind, Manuela Kaspar, et al. · Clinical Cancer Research · 127
Antibody-Based Delivery of Interleukin-2 to Neovasculature Has Potent Activity Against Acute Myeloid Leukemia
2013 · Katrin L. Gutbrodt, Christoph Schliemann, et al. · Science Translational Medicine · 110
A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage 1 1Edited by J. Karn
1999 · Salvatore Demartis, Adrian Huber, et al. · Journal of Molecular Biology · 106
Intralesional Treatment of Stage III Metastatic Melanoma Patients with L19–IL2 Results in Sustained Clinical and Systemic Immunologic Responses
2014 · Benjamin Weide, Thomas K. Eigentler, et al. · Cancer Immunology Research · 99
Phase I/II study of the tumour-targeting human monoclonal antibody–cytokine fusion protein L19-TNF in patients with advanced solid tumours
2012 · G. Spitaleri, R. Berardi, et al. · Journal of Cancer Research and Clinical Oncology · 97
The antibody-based targeted delivery of TNF in combination with doxorubicin eradicates sarcomas in mice and confers protective immunity
2013 · T Hemmerle, P Probst, et al. · British Journal of Cancer · 88
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Isolated limb perfusion with the tumor‐targeting human monoclonal antibody–cytokine fusion protein L19‐TNF plus melphalan and mild hyperthermia in patients with locally advanced extremity melanoma
2012 · Francesco Papadia, Valeria Basso, et al. · Journal of Surgical Oncology · 84
Radretumab Radioimmunotherapy in Patients with Brain Metastasis: A 124I-L19SIP Dosimetric PET Study
2013 · Gian Luca Poli, Claudia Bianchi, et al. · Cancer Immunology Research · 83
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Radioimmunotherapy with Radretumab in Patients with Relapsed Hematologic Malignancies
2012 · Paola A. Erba, Martina Sollini, et al. · Journal of Nuclear Medicine · 80
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The tumor-targeting immunocytokine F16-IL2 in combination with doxorubicin: dose escalation in patients with advanced solid tumors and expansion into patients with metastatic breast cancer
2015 · Chiara Catania, Michela Maur, et al. · Cell Adhesion & Migration · 65
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Phase 0 Microdosing PET Study Using the Human Mini Antibody F16SIP in Head and Neck Cancer Patients
2013 · Derrek A. Heuveling, Remco de Bree, et al. · Journal of Nuclear Medicine · 53
Targeting Interleukin-2 to the Bone Marrow Stroma for Therapy of Acute Myeloid Leukemia Relapsing after Allogeneic Hematopoietic Stem Cell Transplantation
2015 · Christoph Schliemann, Katrin L. Gutbrodt, et al. · Cancer Immunology Research · 49
Expression, engineering and characterization of the tumor-targeting heterodimeric immunocytokine F8-IL12
2010 · Roberto Sommavilla, Nadine Pasche, et al. · Protein Engineering Design and Selection · 42
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Isolation of anti-angiogenesis antibodies from a large combinatorial repertoire by colony filter screening
2001 · L. Giovannoni · Nucleic Acids Research · 42
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Radioimmunotherapy with Tenarad, a 131I-labelled antibody fragment targeting the extra-domain A1 of tenascin-C, in patients with refractory Hodgkin's lymphoma
2014 · Luigi Aloj, Laura D’Ambrosio, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 36
Armed antibodies for cancer treatment: a promising tool in a changing era
2014 · Riccardo Danielli, Roberto Patuzzo, et al. · Cancer Immunology Immunotherapy · 34
A phase IB clinical trial with Dekavil (F8-IL10), an immunoregulatory 'armed antibody' for the treatment of rheumatoid arthritis, used in combination wiIh methotrexate.
2014 · M Galeazzi, L Bazzichi, et al. · PubMed · 34
Abundant in vitro expression of the oncofetal ED-B-containing fibronectin translates into selective pharmacodelivery of 131I-L19SIP in a prostate cancer patient
2013 · Ricarda Locher, Paola A. Erba, et al. · Journal of Cancer Research and Clinical Oncology · 31
A general method for the selection of high-level scFv and IgG antibody expression by stably transfected mammalian cells
2008 · K. Zuberbuhler, A. Palumbo, et al. · Protein Engineering Design and Selection · 31
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Works count: 76
Citation count: 2,633
H-index: 26
I10-index: 30
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