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Joanna Obacz
Observed name:
Obacz, Joanna
Observed institutions:
Inserm,
Slovak Academy of Sciences,
University of Cambridge,
Oncogenesis Stress Signaling,
Centre Eugène Marquis,
Masaryk Memorial Cancer Institute,
Institute of Virology of the Slovak Academy of Sciences,
Université Rennes 1,
Université de Rennes
show all 9
ORCID:
0000-0002-4539-9946
Observed ORCID:
0000-0002-4539-9946
OpenAlex ID:
A5047183222
Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
2018
·
Susan E. Logue
, Eoghan P. McGrath
, et al.
·
Nature Communications
·
283
PDF
Dual IRE1 RNase functions dictate glioblastoma development
2018
·
Stéphanie Lhomond
, Tony Avril
, et al.
·
EMBO Molecular Medicine
·
176
PDF
Endoplasmic reticulum proteostasis in glioblastoma—From molecular mechanisms to therapeutic perspectives
2017
·
Joanna Obacz
, Tony Avril
, et al.
·
Science Signaling
·
139
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity
2023
·
Andrew A. Guirguis
, Yaara Ofir-Rosenfeld
, et al.
·
Cancer Discovery
·
131
Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation
2019
·
Marion Maurel
, Joanna Obacz
, et al.
·
EMBO Molecular Medicine
·
89
PDF
Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses
2013
·
Joanna Obacz
, Silvia Pastorekova
, et al.
·
Molecular Cancer
·
89
PDF
Regulation of tumor–stroma interactions by the unfolded protein response
2017
·
Joanna Obacz
, Tony Avril
, et al.
·
FEBS Journal
·
56
The role of AGR2 and AGR3 in cancer: Similar but not identical
2015
·
Joanna Obacz
, Martina Takacova
, et al.
·
European Journal of Cell Biology
·
56
CD90 Expression Controls Migration and Predicts Dasatinib Response in Glioblastoma
2017
·
Tony Avril
, Amandine Etcheverry
, et al.
·
Clinical Cancer Research
·
50
Enhancing Drug Delivery Efficacy Through Bilayer Coating of Zirconium-Based Metal–Organic Frameworks: Sustained Release and Improved Chemical Stability and Cellular Uptake for Cancer Therapy
2024
·
Xiewen Liu
, Joanna Obacz
, et al.
·
Chemistry of Materials
·
40
Use of preclinical models for malignant pleural mesothelioma
2021
·
Marie Shamseddin
, Joanna Obacz
, et al.
·
Thorax
·
32
PDF
Biological basis for novel mesothelioma therapies
2021
·
Joanna Obacz
, Henry Yung
, et al.
·
British Journal of Cancer
·
31
PDF
IRE1 endoribonuclease signaling promotes myeloid cell infiltration in glioblastoma
2023
·
Joanna Obacz
, Jérôme Archambeau
, et al.
·
Neuro-Oncology
·
25
PDF
Extracellular AGR3 regulates breast cancer cells migration via Src signaling
2019
·
Joanna Obacz
, Lucia Sommerova
, et al.
·
Oncology Letters
·
23
PDF
Anterior gradient protein 3 is associated with less aggressive tumors and better outcome of breast cancer patients
2015
·
Roman Hrstka
, Joanna Obacz
, et al.
·
OncoTargets and Therapy
·
23
PDF
Tamoxifen-Dependent Induction of AGR2 Is Associated with Increased Aggressiveness of Endometrial Cancer Cells
2017
·
Roman Hrstka
, Jan Podhorec
, et al.
·
Cancer Investigation
·
19
Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma
2024
·
Joanna Obacz
, Jose Antonio Valer
, et al.
·
European Respiratory Journal
·
16
PDF
Dual IRE1 RNase functions dictate glioblastoma development
2022
·
Stéphanie Lhomond
, Tony Avril
, et al.
·
EMBO Molecular Medicine
·
15
Erratum To: Dual IRE1 RNase functions dictate glioblastoma development
2023
·
Stéphanie Lhomond
, Tony Avril
, et al.
·
EMBO Molecular Medicine
·
6
Novel IRE1-dependent proinflammatory signaling controls tumor infiltration by myeloid cells
2019
·
Joanna Obacz
, Jérôme Archambeau
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
6
PDF
Inhibition of METTL3 by STC-15 induces RNA misprocessing that results in dsRNA formation and activates innate immunity
2025
·
Harry Fischl
, Tamsin J Samuels
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
5
Data from Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity
2023
·
Andrew A. Guirguis
, Yaara Ofir-Rosenfeld
, et al.
·
2
Abstract C077: STC-15, a small molecule inhibitor of the RNA methyltransferase METTL3, activates anti-tumor immunity and reshapes the tumor microenvironment
2023
·
Yaara Ofir-Rosenfeld
, Lina Vasiliauskaitė
, et al.
·
Molecular Cancer Therapeutics
·
1
Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma
2022
·
Joanna Obacz
, Reshma Nibhani
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
PDF
Abstract 3053: Combination of the MDM2 antagonist ASTX295 and Olaparib as a novel treatment option for BRCA2 mutant, TP53 wild-type solid tumors
2026
·
Antonio Morales
, Joanna Obacz
, et al.
·
Cancer Research
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Works count:
124
Citation count:
1,314
H-index:
16
I10-index:
18
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