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Ruby L.C. Hoo

Observed names: Hoo, Ruby, R. L. C. Hoo, R.L.C. Hoo, Ruby C.L. Hoo, Ruby L C Hoo, Ruby L. C. Hoo, Ruby LC Hoo, Ruby Lai Chong Hoo, Ruby Lai-Chong Hoo, Ruby Lai-chong Hoo, Ruby Lai‐Chong Hoo, RubyLaiChong Hoo, Ruby C.L. Hoo, Ruby L. C. Hoo, Ruby L.-C. Hoo, Ruby L.C. Hoo
ORCID: 0000-0001-9633-7078
Observed ORCID: 0000-0001-9633-7078
OpenAlex ID: A5047335684
Adiponectin Mediates the Metabolic Effects of FGF21 on Glucose Homeostasis and Insulin Sensitivity in Mice
2013 · Zhuofeng Lin, Haishan Tian, et al. · Cell Metabolism · 690
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Lipocalin-2 Is an Inflammatory Marker Closely Associated with Obesity, Insulin Resistance, and Hyperglycemia in Humans
2006 · Yu Wang, Karen S L Lam, et al. · Clinical Chemistry · 577
Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation
2019 · Yong Pan, Xiaoyan Hui, et al. · Journal of Clinical Investigation · 494
Testosterone Selectively Reduces the High Molecular Weight Form of Adiponectin by Inhibiting Its Secretion from Adipocytes
2005 · Aimin Xu, Kok Weng Chan, et al. · Journal of Biological Chemistry · 419
Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin
2014 · Suk Yu Yau, Ang Li, et al. · Proceedings of the National Academy of Sciences · 326
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice
2005 · Aimin Xu, Michael C. Lam, et al. · Proceedings of the National Academy of Sciences · 315
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Adiponectin Modulates the Glycogen Synthase Kinase-3β/β-Catenin Signaling Pathway and Attenuates Mammary Tumorigenesis of MDA-MB-231 Cells in Nude Mice
2006 · Yu Wang, Janice B. Lam, et al. · Cancer Research · 271
Post-translational Modifications of the Four Conserved Lysine Residues within the Collagenous Domain of Adiponectin Are Required for the Formation of Its High Molecular Weight Oligomeric Complex
2006 · Yu Wang, Karen S.L. Lam, et al. · Journal of Biological Chemistry · 256
Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes
2006 · Baoying Chen, Karen S.L. Lam, et al. · Biochemical and Biophysical Research Communications · 238
Chronic adiponectin deficiency leads to Alzheimer’s disease-like cognitive impairments and pathologies through AMPK inactivation and cerebral insulin resistance in aged mice
2016 · Roy Chun-Laam Ng, On-Yin Cheng, et al. · Molecular Neurodegeneration · 183
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Growth Hormone Induces Hepatic Production of Fibroblast Growth Factor 21 through a Mechanism Dependent on Lipolysis in Adipocytes
2011 · Wei Chen, Ruby Lai-chong Hoo, et al. · Journal of Biological Chemistry · 140
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CRAF Methylation by PRMT6 Regulates Aerobic Glycolysis–Driven Hepatocarcinogenesis via ERK‐Dependent PKM2 Nuclear Relocalization and Activation
2019 · Tin‐Lok Wong, Kai‐Yu Ng, et al. · Hepatology · 130
Adiponectin Is Required for PPARγ-Mediated Improvement of Endothelial Function in Diabetic Mice
2011 · Wing Tak Wong, Xiao Yu Tian, et al. · Cell Metabolism · 115
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Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16INK4A Signaling Pathway
2010 · Junlei Chang, Yiming Li, et al. · Diabetes · 113
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An MMP-9 exclusive neutralizing antibody attenuates blood-brain barrier breakdown in mice with stroke and reduces stroke patient-derived MMP-9 activity
2023 · Yabin Ji, Qiang Gao, et al. · Pharmacological Research · 109
Adipocyte fatty acid-binding protein exacerbates cerebral ischaemia injury by disrupting the blood–brain barrier
2020 · Boya Liao, Leiluo Geng, et al. · European Heart Journal · 107
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Selective Elevation of Adiponectin Production by the Natural Compounds Derived from a Medicinal Herb Alleviates Insulin Resistance and Glucose Intolerance in Obese Mice
2008 · Aimin Xu, Hongbing Wang, et al. · Endocrinology · 106
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Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells
2021 · Xiaoping Wu, Lingling Shu, et al. · Advanced Science · 101
A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes
2017 · Lingling Shu, Ruby L. C. Hoo, et al. · Nature Communications · 101
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The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti-inflammatory activity
2010 · Ruby LC Hoo, Janice YL Wong, et al. · Nutrition & Metabolism · 101
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The Novel Perspectives of Adipokines on Brain Health
2019 · Thomas Ho-yin Lee, Kenneth King-yip Cheng, et al. · International Journal of Molecular Sciences · 100
Thiazolidinedione increases serum soluble receptor for advanced glycation end-products in type 2 diabetes
2007 · K. C. B. Tan, W. S. Chow, et al. · Diabetologia · 91
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The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages
2021 · Kelvin Ka Lok Wu, KeKao Long, et al. · Nature Communications · 90
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Pharmacological inhibition of adipocyte fatty acid binding protein alleviates both acute liver injury and non-alcoholic steatohepatitis in mice
2012 · Ruby L.C. Hoo, Ida P.C. Lee, et al. · Journal of Hepatology · 90
Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury†
2008 · Mingyan Zhou, Aimin Xu, et al. · Hepatology · 82
Works count: 74
Citation count: 6,235
H-index: 34
I10-index: 50
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