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Author

Edward Pokrishevsky

Observed name: Pokrishevsky, Edward
ORCID: 0000-0003-4051-8878
Observed ORCID: 0000-0003-4051-8878
OpenAlex ID: A5047398548
Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms
2014 · Leslie I. Grad, Justin J. Yerbury, et al. · Proceedings of the National Academy of Sciences · 433
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Intermolecular transmission of superoxide dismutase 1 misfolding in living cells
2011 · Leslie I. Grad, Will C. Guest, et al. · Proceedings of the National Academy of Sciences · 272
Aberrant Localization of FUS and TDP43 Is Associated with Misfolding of SOD1 in Amyotrophic Lateral Sclerosis
2012 · Edward Pokrishevsky, Leslie I. Grad, et al. · PLoS ONE · 183
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TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion
2016 · Edward Pokrishevsky, Leslie I. Grad, et al. · Scientific Reports · 92
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Generalization of the Prion Hypothesis to Other Neurodegenerative Diseases: An Imperfect Fit
2011 · Will C. Guest, J. Maxwell Silverman, et al. · Journal of Toxicology and Environmental Health · 66
Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding
2014 · Leslie I Grad, Edward Pokrishevsky, et al. · Prion · 55
Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells
2018 · Edward Pokrishevsky, Luke McAlary, et al. · Scientific Reports · 45
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Spinal cord homogenates from SOD1 familial amyotrophic lateral sclerosis induce SOD1 aggregation in living cells
2017 · Edward Pokrishevsky, Ran Ha Hong, et al. · PLoS ONE · 41
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Tryptophan 32 mediates SOD1 toxicity in a in vivo motor neuron model of ALS and is a promising target for small molecule therapeutics
2018 · Michèle G. DuVal, Vijaya K. Hinge, et al. · Neurobiology of Disease · 36
Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1
2024 · Edward Pokrishevsky, Michéle G. DuVal, et al. · Journal of Biological Chemistry · 12
Intercellular Prion-Like Conversion and Transmission of Cu/Zn Superoxide Dismutase (SOD1) in Cell Culture
2017 · Leslie I. Grad, Edward Pokrishevsky, et al. · Methods in molecular biology · 5
Induction of Cu/Zn Superoxide Dismutase (SOD1) Aggregation in Living Cells
2018 · Edward Pokrishevsky, Jeremy Nan, et al. · Methods in molecular biology · 2
P4‐163: the Pathological Interactome of Tdp‐43 Includes Human Wildtype Sod1
2019 · Edward Pokrishevsky, Michele DuVal, et al. · Alzheimer s & Dementia
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Induction of wild-type SOD1 misfolding, aggregation and its cell-to-cell propagation
2019 · Pokrishevsky, Edward · cIRcle (University of British Columbia)
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Aberrant localization of fused in sarcoma (FUS) and TAR DNA binding protein (TDP)-43 triggers misfolding of human Cu/Zn superoxide dismutase (SOD1)
2011 · Pokrishevsky, Edward · cIRcle (University of British Columbia)
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Works count: 15
Citation count: 1,242
H-index: 10
I10-index: 10
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