Author

Earl V. Martin

Observed names: E Martin, E. Martin, E. V. MARTIN, Earl Martin

Institution: Mount Saint Vincent University

Observed institutions: Dalhousie University, Mount Saint Vincent University, National Research Council Canada, University of Nebraska Medical Center

ORCID: 0009-0005-9144-046X

Observed ORCID: 0009-0005-9144-046X

OpenAlex ID: A5047406282

Carbamates with Differential Mechanism of Inhibition Toward Acetylcholinesterase and Butyrylcholinesterase

2008 · Sultan Darvesh, Katherine V. Darvesh, et al. · Journal of Medicinal Chemistry · 158

Inhibition of Human Cholinesterases by Drugs Used to Treat Alzheimer Disease

2003 · Sultan Darvesh, Ryan Walsh, et al. · Alzheimer Disease & Associated Disorders · 157

Butyrylcholinesterase Is Associated With β-Amyloid Plaques in the Transgenic APP SWE /PSEN1dE9 Mouse Model of Alzheimer Disease

2011 · Sultan Darvesh, Meghan K. Cash, et al. · Journal of Neuropathology & Experimental Neurology · 153

Cholinesterase Inhibition in Alzheimer's Disease: Is Specificity the Answer?

2014 · Ian R. Macdonald, Kenneth Rockwood, et al. · Journal of Alzheimer s Disease · 84

Early Detection of Cerebral Glucose Uptake Changes in the 5XFAD Mouse

2014 · I.R. Macdonald, D.R. DeBay, et al. · Current Alzheimer Research · 82

Probing the Peripheral Site of Human Butyrylcholinesterase

2012 · Ian R. Macdonald, Earl Martin, et al. · Biochemistry · 78

Structure–activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives

2004 · Sultan Darvesh, Robert S. McDonald, et al. · Bioorganic & Medicinal Chemistry · 58

Selective reversible inhibition of human butyrylcholinesterase by aryl amide derivatives of phenothiazine

2007 · Sultan Darvesh, Robert S. McDonald, et al. · Bioorganic & Medicinal Chemistry · 53

Biochemical and Histochemical Comparison of Cholinesterases in Normal and Alzheimer Brain Tissues

2010 · S. Darvesh, G.A. Reid, et al. · Current Alzheimer Research · 45

Distribution of phospholipids around gramicidin and D-.beta.-hydroxybutyrate dehydrogenase as measured by resonance energy transfer

1988 · Suke Wang, Earl Martin, et al. · Biochemistry · 43

On the active site for hydrolysis of aryl amides and choline esters by human cholinesterases

2006 · Sultan Darvesh, Robert S. McDonald, et al. · Bioorganic & Medicinal Chemistry · 42

Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants

2010 · Sultan Darvesh, Ian R. Pottie, et al. · Bioorganic & Medicinal Chemistry · 41

A method to describe enzyme-catalyzed reactions by combining steady state and time course enzyme kinetic parameters

2009 · Ryan Walsh, Earl Martin, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 37

Differential effects of lipid-lowering agents on human cholinesterases

2003 · Sultan Darvesh, Earl Martin, et al. · Clinical Biochemistry · 37

Synergistic inhibition of butyrylcholinesterase by galantamine and citalopram

2011 · Ryan Walsh, Kenneth Rockwood, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 35

Butyrylcholinesterase-knockout reduces fibrillar β-amyloid and conserves 18FDG retention in 5XFAD mouse model of Alzheimer’s disease

2017 · Drew R. DeBay, George A. Reid, et al. · Brain Research · 33

A versatile equation to describe reversible enzyme inhibition and activation kinetics: Modeling β-galactosidase and butyrylcholinesterase

2007 · Ryan Walsh, Earl Martin, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 30

Butyrylcholinesterase-Mediated Enhancement of the Enzymatic Activity of Trypsin

2001 · Sultan Darvesh, Rohit Kumar, et al. · Cellular and Molecular Neurobiology · 29

Homocysteine Thiolactone and Human Cholinesterases

2006 · Sultan Darvesh, Ryan Walsh, et al. · Cellular and Molecular Neurobiology · 28

Targeting butyrylcholinesterase for preclinical single photon emission computed tomography (SPECT) imaging of Alzheimer's disease

2017 · Drew R. DeBay, George A. Reid, et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions · 27

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The kinetics and equilibrium of the hydration of phthalaldehyde

1979 · Robert S. McDonald, Earl V. Martin · Canadian Journal of Chemistry · 26

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Limitations of conventional inhibitor classifications

2011 · Ryan Walsh, Earl Martin, et al. · Integrative Biology · 24

Cholinesterases in cardiac ganglia and modulation of canine intrinsic cardiac neuronal activity

1998 · S Darvesh, S.E MacDonald, et al. · Journal of the Autonomic Nervous System · 24

Cholinesterase inhibitors modify the activity of intrinsic cardiac neurons

2004 · Sultan Darvesh, Rakesh C. Arora, et al. · Experimental Neurology · 19

Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems

2013 · Sultan Darvesh, Ian R. Macdonald, et al. · Bioorganic & Medicinal Chemistry Letters · 18

Works count: 56

Citation count: 1,446

H-index: 23

I10-index: 30