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Michał Mlącki
Observed names:
M. Mlacki,
M. Mlącki,
Michal Mlacki,
Michal Mlącki
Institution:
Molecure SA (Poland)
Observed institutions:
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego,
Hospital Quirón Teknon,
OncoArendi Therapeutics (Poland),
Molecure SA (Poland),
IDCQ Hospitales y Sanidad, S.L.U.,
Polish Academy of Sciences
show all 6
ORCID:
0000-0002-4034-6933
Observed ORCID:
0000-0002-4034-6933
OpenAlex ID:
A5047935758
Works
20
Awards
1
Recent discoveries concerning the involvement of transcription factors from the Grainyhead-like family in cancer
2015
·
Michal Mlacki
, Agnieszka Kikulska
, et al.
·
Experimental Biology and Medicine
·
68
Loss of Grainy Head-Like 1 Is Associated with Disruption of the Epidermal Barrier and Squamous Cell Carcinoma of the Skin
2014
·
Michal Mlacki
, Charbel Darido
, et al.
·
PLoS ONE
·
64
PDF
OATD-02 Validates the Benefits of Pharmacological Inhibition of Arginase 1 and 2 in Cancer
2022
·
Marcin Mikołaj Grzybowski
, Paulina Seweryna Stańczak
, et al.
·
Cancers
·
44
PDF
Metabolomic reprogramming of the tumor microenvironment by dual arginase inhibitor OATD-02 boosts anticancer immunity
2025
·
Marcin Mikołaj Grzybowski
, Yasemin Uçal
, et al.
·
Scientific Reports
·
34
PDF
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis
2020
·
Robert Koralewski
, Barbara Dymek
, et al.
·
Journal of Medicinal Chemistry
·
32
Epithelial-macrophage-dendritic cell interactions impact alarmins expression in asthma and COPD
2020
·
Magdalena Paplinska-Goryca
, Paulina Misiukiewicz-Stepien
, et al.
·
Clinical Immunology
·
29
PDF
Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis
2022
·
Piotr Sklepkiewicz
, Barbara A. Dymek
, et al.
·
European Journal of Pharmacology
·
27
Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis
2022
·
Barbara Dymek
, Piotr Sklepkiewicz
, et al.
·
Journal of Inflammation Research
·
22
PDF
Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma
2023
·
Piotr Sklepkiewicz
, Barbara Dymek
, et al.
·
International Journal of Molecular Sciences
·
17
PDF
S100A6 activates EGFR and its downstream signaling in HaCaT keratinocytes
2019
·
Agnieszka Graczyk‐Jarzynka
, Barbara Sobiak
, et al.
·
Journal of Cellular Physiology
·
14
CHIT1 is a novel therapeutic target in idiopathic pulmonary fibrosis (IPF): anti-fibrotic efficacy of OATD-01, a potent and selective chitinase inhibitor in the mouse model of pulmonary fibrosis
2018
·
Barbara Dymek
, Piotr Sklepkiewicz
, et al.
·
European Respiratory Journal
·
10
Consequences of the loss of the Grainyhead-like 1 gene for renal gene expression, regulation of blood pressure and heart rate in a mouse model
2015
·
Magdalena Pawlak
, Agnieszka Walkowska
, et al.
·
Acta Biochimica Polonica
·
10
Chitinase-1 inhibition attenuates metabolic dysregulation and restores homeostasis in MASH animal models
2025
·
Katarzyna Drzewicka
, Katarzyna M. Głuchowska
, et al.
·
Frontiers in Immunology
·
4
PDF
Threonine 454 phosphorylation in Grainyhead-like 3 is important for its function and regulation by the p38 MAPK pathway
2018
·
Ewa Krzywinska
, Marek Dominick Zorawski
, et al.
·
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
·
2
PDF
Exploring CHIT1 and YKL-40 in tuberculous pleural effusion: Insights and implications
2025
·
Natalia Przysucha
, Magdalena Paplińska-Goryca
, et al.
·
Tuberculosis
·
1
Therapeutic efficacy of the chitotriosidase inhibitors in STAM model of non-alcoholic steatohepatitis
2020
·
Michal Mlacki
, Barbara Dymek
, et al.
·
Journal of Hepatology
·
1
PDF
The therapeutic efficacy of OAT-889 (dual AMCase/CHIT1 inhibitor) in comparison to montelukast in HDM-induced model of chronic airway inflammation in mice
2017
·
Barbara Dymek
, Piotr Sklepkiewicz
, et al.
·
European Respiratory Journal
·
1
Chitinase-1 Inhibition Reverses Metabolic Dysregulation and Restores Homeostasis in MASH Animal Models
2024
·
Katarzyna Drzewicka
, Katarzyna Głuchowska
, et al.
·
SSRN Electronic Journal
1689P OATD-02 validates the benefits of pharmacological inhibition of arginase 1 and 2 in cancer
2022
·
M.M. Grzybowski
, R. Blaszczyk
, et al.
·
Annals of Oncology
PDF
Clinical Development of OATD-01 - a Novel, Chitinase Inhibitor for Treatment of Interstitial Lung Diseases
2019
·
R. Dyjas
, J. Lipner
, et al.
·
American Journal of Respiratory and Critical Care Medicine
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Works count:
20
Citation count:
380
H-index:
10
I10-index:
12
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