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Stephen J Harper

Observed names: Harper, Stephen, S. Harper, S. J. Harper, Stephen Harper
ORCID: 0000-0002-6029-8668
Observed ORCID: 0000-0002-6029-8668
OpenAlex ID: A5048042636
Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
2022 · Andrew Poole, Vijaykumar Karuppiah, et al. · Nature Communications · 115
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Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA
2020 · Christopher J. Holland, Rory M. Crean, et al. · Journal of Clinical Investigation · 93
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Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains
2014 · Stephen Harper, Hayley E. Gratton, et al. · Biochemistry · 54
TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide–HLA Complex
2020 · Charlotte H Coles, Rachel M Mulvaney, et al. · The Journal of Immunology · 53
Structural characterization of the apo form and NADH binary complex of human lactate dehydrogenase
2014 · Sally Dempster, Stephen Harper, et al. · Acta Crystallographica Section D Biological Crystallography · 30
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T-cell receptor structures and predictive models reveal comparable alpha and beta chain structural diversity despite differing genetic complexity
2025 · Nele P. Quast, Brennan Abanades, et al. · Communications Biology · 29
T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4
2020 · Charlotte H. Coles, Catriona McMurran, et al. · Journal of Biological Chemistry · 29
Structure of the USP15 N-Terminal Domains: A β-Hairpin Mediates Close Association between the DUSP and UBL Domains
2011 · Stephen Harper, Tabot M. D. Besong, et al. · Biochemistry · 27
Tuning the potency and selectivity of ImmTAC molecules by affinity modulation
2023 · Ian B Robertson, Rachel Mulvaney, et al. · Clinical & Experimental Immunology · 22
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Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy
2020 · Rory M. Crean, Bruce J. MacLachlan, et al. · Molecular Therapy — Oncolytics · 16
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Unconventional modes of peptide–HLA-I presentation change the rules of TCR engagement
2022 · Jade R Hopkins, Bruce J MacLachlan, et al. · Discovery Immunology · 15
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Broadening alloselectivity of T cell receptors by structure guided engineering
2024 · Vijaykumar Karuppiah, Dhaval Sangani, et al. · Scientific Reports · 9
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High-affinity T cell receptor ImmTAC® bispecific efficiently redirects T cells to kill tumor cells expressing the cancer–testis antigen PRAME
2024 · Ana R Ribeiro, Camille Britton-Rivet, et al. · Immunotherapy Advances · 8
Determining T-cell receptor binding orientation and Peptide-HLA interactions using cross-linking mass spectrometry
2025 · Thomas Powell, Vijaykumar Karuppiah, et al. · Journal of Biological Chemistry · 4
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Abstract 2271: Tebentafusp recognition of melanoma cells is restricted by HLA-A0201 presentation of a gp100 peptide
2020 · David Cole, Ross Robinson, et al. · Cancer Research · 1
Assay limitations of osmotic reflection coefficient of isolated mouse glomeruli ex vivo.
2009 · Leslie May Sage, David O Bates, et al. · The FASEB Journal · 1
Crystal structure of the T-cell receptor GVY01 bound to HLA A2*01-GVYDGREHTV
2019 · C.H. Coles, C. McMurran, et al. · Worldwide Protein Data Bank
Crystal structure of the T-cell receptor NYE_S2 bound to HLA A2*01-SLLMWITQV
2019 · C.H. Coles, R. Mulvaney, et al. · Worldwide Protein Data Bank
Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV
2019 · C.H. Coles, R. Mulvaney, et al. · Worldwide Protein Data Bank
Structural Characterisation of the Apo-form of Human Lactate Dehydrogenase M Isozyme
2013 · S. Dempster, S. Harper, et al. · Worldwide Protein Data Bank
Structural characterisation of the NADH binary complex of human lactate dehydrogenase M isozyme
2013 · S. Dempster, S. Harper, et al. · Worldwide Protein Data Bank
Glucose is the component of diabetic plasma that increases vascular permeability
2006 · Rachel Morvah Perrin, Stephen J Harper, et al. · The FASEB Journal
PC34 ANTIBODIES SPECIFIC TO THE C TERMINUS OF VEGF165b, DETECT PROTEIN IN NORMAL HUMAN PLASMA
2004 · Y. Qiu, R. M. Perrin, et al. · Microcirculation
Works count: 24
Citation count: 508
H-index: 11
I10-index: 11
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