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Shawn P. Maddaford

Observed names: S. MADDAFORD, S. Maddaford, S. P. MADDAFORD, Shawn Maddaford, Shawn. P. Maddaford
Observed institutions: University of Calgary, University of Toronto, York University, NeurAxon (Canada), Talon Pharmaceuticals (Canada), MaRS, Hôpital Saint-François d'Assise, Université Laval, University of Manitoba
OpenAlex ID: A5048557604
Triptan-induced enhancement of neuronal nitric oxide synthase in trigeminal ganglion dural afferents underlies increased responsiveness to potential migraine triggers
2010 · M. De Felice, M. H. Ossipov, et al. · Brain · 133
Palladium(II) Acetate Catalyzed Stereoselective C -Glycosidation of Peracetylated Glycals with Arylboronic Acids
2001 · Jailall Ramnauth, Odile Poulin, et al. · Organic Letters · 124
Total Synthesis of (+)-Xestoquinone Using an Asymmetric Palladium-Catalyzed Polyene Cyclization
1996 · Shawn P. Maddaford, Neil G. Andersen, et al. · Journal of the American Chemical Society · 111
Stereoselective C -Glycoside Formation by a Rhodium(I)-Catalyzed 1,4-Addition of Arylboronic Acids to Acetylated Enones Derived from Glycals
2001 · Jailall Ramnauth, Odile Poulin, et al. · Organic Letters · 83
A Modified in Situ Suzuki Cross-Coupling of Haloarenes for the Preparation of C2-Symmetric Biaryls
1996 · Neil G. Andersen, Shawn P. Maddaford, et al. · The Journal of Organic Chemistry · 75
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Scope and Limitations of the Palladium-Catalyzed Cross-Coupling Reaction of in situ Generated Organoboranes with Aryl and Vinyl Halides
1994 · Shawn P. Maddaford, Brian A. Keay · The Journal of Organic Chemistry · 66
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Discovery ofcis-N-(1-(4-(Methylamino)cyclohexyl)indolin-6-yl)thiophene-2-carboximidamide: A 1,6-Disubstituted Indoline Derivative as a Highly Selective Inhibitor of Human Neuronal Nitric Oxide Synthase (nNOS) without Any Cardiovascular Liabilities
2011 · Subhash C. Annedi, Jailall Ramnauth, et al. · Journal of Medicinal Chemistry · 41
Synthesis of Functionalized Naphthalenes from Substituted 1-Methoxybenzocyclobutenes
1996 · Neil G. Andersen, Shawn P. Maddaford, et al. · The Journal of Organic Chemistry · 38
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Discovery ofN-(3-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl) thiophene-2-carboximidamide as a Selective Inhibitor of Human Neuronal Nitric Oxide Synthase (nNOS) for the Treatment of Pain
2011 · Subhash C. Annedi, Shawn P. Maddaford, et al. · Journal of Medicinal Chemistry · 33
Design, Synthesis, and Biological Evaluation of 3,4-Dihydroquinolin-2(1H)-one and 1,2,3,4-Tetrahydroquinoline-Based Selective Human Neuronal Nitric Oxide Synthase (nNOS) Inhibitors
2011 · Jailall Ramnauth, Joanne Speed, et al. · Journal of Medicinal Chemistry · 33
Novel 2-aminobenzothiazoles as selective neuronal nitric oxide synthase inhibitors
2007 · Joanne Patman, Namrta Bhardwaj, et al. · Bioorganic & Medicinal Chemistry Letters · 33
Chapter 2 Advancements in the Development of Nitric Oxide Synthase Inhibitors
2009 · Shawn Maddaford, Subhash C. Annedi, et al. · Annual reports in medicinal chemistry · 31
A Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA) of Anthranilamide Derivatives That Are Multidrug Resistance Modulators
2006 · Philippe Labrie, Shawn P. Maddaford, et al. · Journal of Medicinal Chemistry · 31
A general asymmetric synthesis of (-)-.alpha.-dimethylretrodendrin and its diastereomers
1993 · Shawn P. Maddaford, James L. Charlton · The Journal of Organic Chemistry · 30
In vitro activity of novel dual action MDR anthranilamide modulators with inhibitory activity at CYP-450
2006 · Philippe Labrie, Shawn. P. Maddaford, et al. · Bioorganic & Medicinal Chemistry · 25
Effect of the glycine transporter 1 inhibitor ALX-5407 on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset
2021 · Imane Frouni, Sébastien Belliveau, et al. · European Journal of Pharmacology · 24
NOpiates: Novel Dual Action Neuronal Nitric Oxide Synthase Inhibitors with μ-Opioid Agonist Activity
2012 · Paul Renton, Brenda Green, et al. · ACS Medicinal Chemistry Letters · 24
Discovery of a potent, orally bioavailable and highly selective human neuronal nitric oxide synthase (nNOS) inhibitor, N-(1-(piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide as a pre-clinical development candidate for the treatment of migraine
2012 · Subhash C. Annedi, Shawn P. Maddaford, et al. · European Journal of Medicinal Chemistry · 23
In vitro activity of novel dual action MDR anthranilamide modulators with inhibitory activity on CYP-450 (Part 2)
2007 · Philippe Labrie, Shawn P. Maddaford, et al. · Bioorganic & Medicinal Chemistry · 23
Identification of a novel non-carbohydrate molecule that binds to the ribosomal A-site RNA
2004 · Shawn P. Maddaford, Mina Motamed, et al. · Bioorganic & Medicinal Chemistry Letters · 21
1,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors
2011 · Paul Renton, Joanne Speed, et al. · Bioorganic & Medicinal Chemistry Letters · 20
First-in-Class, Dual-Action, 3,5-Disubstituted Indole Derivatives Having Human Nitric Oxide Synthase (nNOS) and Norepinephrine Reuptake Inhibitory (NERI) Activity for the Treatment of Neuropathic Pain
2012 · Gabriela Mladenova, Subhash C. Annedi, et al. · Journal of Medicinal Chemistry · 18
3,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase (nNOS) inhibitors
2012 · Subhash C. Annedi, Shawn P. Maddaford, et al. · Bioorganic & Medicinal Chemistry Letters · 18
1,6-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors
2011 · Shawn Maddaford, Paul Renton, et al. · Bioorganic & Medicinal Chemistry Letters · 17
1996 Merck Frosst Award Lecture Synthetic adventures along a Rocky Mountain road
1997 · Brian A. Keay, Shawn P. Maddaford, et al. · Canadian Journal of Chemistry · 17
Works count: 45
Citation count: 1,177
H-index: 20
I10-index: 29
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