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Daisuke Iejima

Enhanced optineurin E50K–TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma
2013 · Yuriko Minegishi, Daisuke Iejima, et al. · Human Molecular Genetics · 144
Significance of optineurin mutations in glaucoma and other diseases
2016 · Yuriko Minegishi, Mao Nakayama, et al. · Progress in Retinal and Eye Research · 126
Overexpression of HtrA1 and Exposure to Mainstream Cigarette Smoke Leads to Choroidal Neovascularization and Subretinal Deposits in Aged Mice
2014 · Mao Nakayama, Daisuke Iejima, et al. · Investigative Ophthalmology & Visual Science · 69
CCT2 Mutations Evoke Leber Congenital Amaurosis due to Chaperone Complex Instability
2016 · Yuriko Minegishi, XunLun Sheng, et al. · Scientific Reports · 48
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Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency
2020 · Lizhu Yang, Kaoru Fujinami, et al. · Scientific Reports · 41
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METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma
2022 · Yang Pan, Akiko Suga, et al. · Journal of Clinical Investigation · 39
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Differential Inducibility of Human and Porcine Dental Pulp-Derived Cells into Odontoblasts
2007 · Akiko Tonomura, Yoshinori Sumita, et al. · Connective Tissue Research · 35
HTRA1 (High Temperature Requirement A Serine Peptidase 1) Gene Is Transcriptionally Regulated by Insertion/Deletion Nucleotides Located at the 3′ End of the ARMS2 (Age-related Maculopathy Susceptibility 2) Gene in Patients with Age-related Macular Degeneration
2014 · Daisuke Iejima, Takeshi Itabashi, et al. · Journal of Biological Chemistry · 34
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Clinical and Genetic Characteristics of 18 Patients from 13 Japanese Families with CRX-associated retinal disorder: Identification of Genotype-phenotype Association
2020 · Yu Fujinami-Yokokawa, Kaoru Fujinami, et al. · Scientific Reports · 33
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Novel mutations in the RS1 gene in Japanese patients with X-linked congenital retinoschisis
2019 · Hiroyuki Kondo, Kazuma Oku, et al. · Human Genome Variation · 24
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HTRA1 Overexpression Induces the Exudative Form of Age-related Macular Degeneration.
2015 · Daisuke Iejima, Mao Nakayama, et al. · PubMed · 24
Binding of Gtf2i-β/δ transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in vitro
2021 · Yang Pan, Daisuke Iejima, et al. · Journal of Biological Chemistry · 15
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Novel biallelic loss-of-function KCNV2 variants in cone dystrophy with supernormal rod responses
2019 · Tomoko Kutsuma, Satoshi Katagiri, et al. · Documenta Ophthalmologica · 15
Effect of Timolol on Optineurin Aggregation in Transformed Induced Pluripotent Stem Cells Derived From Patient With Familial Glaucoma
2018 · Satoshi Inagaki, Kazuhide Kawase, et al. · Investigative Ophthalmology & Visual Science · 15
FRS2β, a potential prognostic gene for non-small cell lung cancer, encodes a feedback inhibitor of EGF receptor family members by ERK binding
2010 · D Iejima, Y Minegishi, et al. · Oncogene · 11
The membrane-linked adaptor FRS2β fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis
2021 · Yasuto Takeuchi, Natsuko Kimura, et al. · Proceedings of the National Academy of Sciences · 8
A collagen–phosphophoryn sponge as a scaffold for bone tissue engineering
2003 · Daisuke Iejima, Takashi Saito, et al. · Journal of Biomaterials Science Polymer Edition · 8
Clinical features and molecular mechanisms of RP1L1 variants causing occult macular dystrophy
2025 · Yang Pan, Daisuke Iejima, et al. · Human Genetics and Genomics Advances · 1
Characterization of Optineurin E50K knock-in mouse model with normal tension glaucoma and evaluation of TBK1 inhibitor Amlexanox
2017 · Mao Nakayama, Yuriko Minegishi, et al. · Investigative Ophthalmology & Visual Science · 1
Human HTRA1 expression is enhanced by indel mutation in the HTRA1 regulatory element region.
2015 · Daisuke Iejima, Mao Nakayama, et al. · Investigative Ophthalmology & Visual Science · 1
Abstract 2673: The cytoplasmic adaptor FRS2beta fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis
2021 · Noriko Gotoh, Yasuto Takeuchi, et al. · Cancer Research
Mechanisms of transcriptional regulation of ARMS2/HTRA1 locus as risk factor for age-related macular degeneration
2019 · Takeshi Iwata, Daisuke Iejima, et al. · Investigative Ophthalmology & Visual Science
Critical roles of FRS2beta for creating the cytokine-rich precancerous microenvironment for mammary tumorigenesis
2019 · Tatsunori Nishimura, Natsuko Kimura, et al. · 日本分子生物学会年会プログラム・要旨集(Web)
The oligodendrocyte derived from familial glaucoma patients-iPSCs decreases neuroprotective action for retinal ganglion cells
2018 · Satoshi Inagaki, Kazuhide Kawase, et al. · Investigative Ophthalmology & Visual Science
Function analysis of HTRA1 regulatory element in Patients with Exudative Age-Related Macular Degeneration
2017 · Daisuke Iejima, Takeshi Iwata · Investigative Ophthalmology & Visual Science
Works count: 28
Citation count: 692
H-index: 14
I10-index: 15
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