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Houcemeddine Othman

Observed names: H Othman, H. Othman, Houcemedine Othman, Othman, Houcemeddine
Observed institutions: Tunis University, University of Carthage, University of the Witwatersrand, Hôpital Farhat Hached, Institut Pasteur de Tunis, Faculté de médecine de Tunis, Tunis El Manar University, University of Sousse
ORCID: 0000-0002-1159-6482
Observed ORCID: 0000-0002-1159-6482
OpenAlex ID: A5048842144
Interaction of the spike protein RBD from SARS-CoV-2 with ACE2: Similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphism
2020 · Houcemeddine Othman, Zied Bouslama, et al. · Biochemical and Biophysical Research Communications · 145
The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells
2019 · Ichrak Riahi-Chebbi, Soumaya Souid, et al. · Scientific Reports · 140
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A Review of Clinical Pharmacogenetics Studies in African Populations
2020 · Fouzia Radouani, Lyndon Zass, et al. · Personalized Medicine · 82
Helix aspersa maxima mucus exhibits antimelanogenic and antitumoral effects against melanoma cells
2018 · Chedli Ellijimi, Manel Ben Hammouda, et al. · Biomedicine & Pharmacotherapy · 70
Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression
2016 · Ons Zakraoui, Cezary Marcinkiewicz, et al. · Molecular Carcinogenesis · 69
PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells
2012 · Maram Morjen, Olfa Kallech-ziri, et al. · Matrix Biology · 68
Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides
2018 · Dorra Aissaoui, Saoussen Mlayah-Bellalouna, et al. · International Journal of Biological Macromolecules · 61
Anti-tumoral effect of scorpion peptides: Emerging new cellular targets and signaling pathways
2019 · Najet Srairi-Abid, Houcemeddine Othman, et al. · Cell Calcium · 54
Two distinct conformational states of Mycobacterium tuberculosis virulent factor early secreted antigenic target 6 kD a are behind the discrepancy around its biological functions
2015 · Amira Refai, Meriam Haoues, et al. · FEBS Journal · 40
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The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations
2021 · Jorge da Rocha, Houcemeddine Othman, et al. · Frontiers in Pharmacology · 39
Human OMICs and Computational Biology Research in Africa: Current Challenges and Prospects
2021 · Yosr Hamdi, Lyndon Zass, et al. · OMICS A Journal of Integrative Biology · 37
Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances their sensitivity to cisplatin
2017 · Manel B. Hammouda, Ichrak Riahi-Chebbi, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 34
In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect
2021 · Sondes Haddad-Boubaker, Houcemeddine Othman, et al. · BMC Bioinformatics · 32
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G6PD distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19
2021 · Jorge E. B. da Rocha, Houcemeddine Othman, et al. · The Pharmacogenomics Journal · 28
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In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion
2016 · Houcemeddine Othman, Silke Andrea Wieninger, et al. · Journal of Biomolecular Structure and Dynamics · 28
A thermoactive l-amino acid oxidase from Cerastes cerastes snake venom: Purification, biochemical and molecular characterization
2014 · Zaineb Abdelkafi-Koubaa, Jed Jebali, et al. · Toxicon · 24
SARS-CoV-2 Spike Protein Unlikely to Bind to Integrins via the Arg-Gly-Asp (RGD) Motif of the Receptor Binding Domain: Evidence From Structural Analysis and Microscale Accelerated Molecular Dynamics
2022 · Houcemeddine Othman, Haifa Ben Messaoud, et al. · Frontiers in Molecular Biosciences · 22
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The galactolipase activity of Fusarium solani (phospho)lipase
2014 · Raida Jallouli, Houcemeddine Othman, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 22
AaTs-1: A Tetrapeptide from Androctonus australis Scorpion Venom, Inhibiting U87 Glioblastoma Cells Proliferation by p53 and FPRL-1 Up-Regulations
2021 · Dorra Aissaoui-Zid, Mohamed-Chiheb Saada, et al. · Molecules · 21
Identification of Novel BRCA1 and RAD50 Mutations Associated With Breast Cancer Predisposition in Tunisian Patients
2020 · Najah Mighri, Yosr Hamdi, et al. · Frontiers in Genetics · 20
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AaHIV a sodium channel scorpion toxin inhibits the proliferation of DU145 prostate cancer cells
2019 · Rym BenAissa, Houcemeddine Othman, et al. · Biochemical and Biophysical Research Communications · 19
African Global Representation in Biomedical Sciences
2021 · Nicola Mulder, Lyndon Zass, et al. · Annual Review of Biomedical Data Science · 17
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Genome Tunisia Project: paving the way for precision medicine in North Africa
2024 · Yosr Hamdi, Mediha Trabelsi, et al. · Genome Medicine · 15
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AaTX1, from Androctonus australis scorpion venom: Purification, synthesis and characterization in dopaminergic neurons
2014 · Saoussen Mlayah-Bellalouna, Martial Dufour, et al. · Toxicon · 15
An Integrative Computational Approach for the Prediction of Human‐Plasmodium Protein‐Protein Interactions
2020 · Kais Ghedira, Yosr Hamdi, et al. · BioMed Research International · 12
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Works count: 90
Citation count: 1,310
H-index: 20
I10-index: 32
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