Author

Thierry Defrance

Observed names: DEFRANCE, Thierry, Defrance, T DeFrance, T Defrance, T. Defrance, TH. DEFRANCE, THIERRY DEFRANCE, Thierry DeFrance, Thierry T. Defrance

Institutions: Lyon 1 Université, École Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Inserm, Université de Lyon, Hospices Civils de Lyon, Hôpital Edouard Herriot, Centre International de Recherche en Infectiologie

Observed institutions: Lyon 1 Université, École Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Inserm, Institut Pasteur, Université de Lyon, Centre de Recherche des Cordeliers, Hospices Civils de Lyon, Hôpital Edouard Herriot, Centre International de Recherche en Infectiologie, Hôpital Albert Michallon, Structure Fédérative de Recherche Biosciences, Université Jean Monnet, University of Reggio Calabria, University of Naples Federico II, Institut Curie, Université Jean Monnet, University of Amsterdam

ORCID: 0000-0002-6943-358X

Observed ORCID: 0000-0002-6943-358X

OpenAlex ID: A5048916540

Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes.

1992 · F Rousset, E Garcia, et al. · Proceedings of the National Academy of Sciences · 1,238

Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.

1992 · T Defrance, B Vanbervliet, et al. · The Journal of Experimental Medicine · 638

Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities.

1986 · T Yokota, T Otsuka, et al. · Proceedings of the National Academy of Sciences · 501

Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

1987 · T Defrance, J P Aubry, et al. · The Journal of Experimental Medicine · 446

TLR Agonists Selectively Promote Terminal Plasma Cell Differentiation of B Cell Subsets Specialized in Thymus-Independent Responses

2007 · Laurent Genestier, Morgan Taillardet, et al. · The Journal of Immunology · 319

Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway

2003 · Catherine Kern, Jean-François Cornuel, et al. · Blood · 314

Interleukin 13 is a B cell stimulating factor.

1994 · T Defrance, P Carayon, et al. · The Journal of Experimental Medicine · 294

Activation of human B lymphocytes through CD40 and interleukin 4

1989 · Alain Vallé, Caroline E. Zuber, et al. · European Journal of Immunology · 221

Immunogenicity and efficacy of heterologous ChAdOx1–BNT162b2 vaccination

2021 · Bruno Pozzetto, Vincent Legros, et al. · Nature · 210

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Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants

2019 · Alice Koenig, Chien-Chia Chen, et al. · Nature Communications · 208

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B cell growth-promoting activity of recombinant human interleukin 4.

1987 · T Defrance, B Vanbervliet, et al. · The Journal of Immunology · 205

Modulation and Functional Involvement of CB2 Peripheral Cannabinoid Receptors During B-Cell Differentiation

1998 · Pierre Carayon, Jean Marchand, et al. · Blood · 178

Triggering of CD40 Antigen Inhibits Fludarabine-Induced Apoptosis in B Chronic Lymphocytic Leukemia Cells

1998 · Maria Fiammetta Romano, Annalisa Lamberti, et al. · Blood · 144

T cell-independent B cell memory

2011 · Thierry Defrance, Morgan Taillardet, et al. · Current Opinion in Immunology · 141

Regulation of Fc receptor for IgE (CD23) and class II MHC antigen expression on Burkitt's lymphoma cell lines by human IL-4 and IFN-gamma.

1988 · F Rousset, R W Malefijt, et al. · The Journal of Immunology · 139

Responsiveness of chronic lymphocytic leukemia B cells activated via surface Igs or CD40 to B-cell tropic factors

1992 · AC Fluckiger, JF Rossi, et al. · Blood · 136

Flice-Inhibitory Protein Is a Key Regulator of Germinal Center B Cell Apoptosis

2001 · Ana Hennino, Marion Bérard, et al. · The Journal of Experimental Medicine · 125

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The TLR1/2 agonist PAM3CSK4 instructs commitment of human hematopoietic stem cells to a myeloid cell fate

2009 · K De Luca, V Frances-Duvert, et al. · Leukemia · 123

Interleukin 4 counteracts the interleukin 2-induced proliferation of monoclonal B cells.

1988 · S Karray, T DeFrance, et al. · The Journal of Experimental Medicine · 123

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Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule.

1995 · C Lagresle, C Bella, et al. · The Journal of Immunology · 122

Human recombinant IL-4 induces activated B lymphocytes to produce IgG and IgM.

1988 · T Defrance, B Vanbervliet, et al. · The Journal of Immunology · 117

Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge

2016 · Pascal Blanc, Ludovic Moro-Sibilot, et al. · Nature Communications · 115

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Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis.

1996 · C Lagresle, P Mondière, et al. · The Journal of Experimental Medicine · 115

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The thymus-independent immunity conferred by a pneumococcal polysaccharide is mediated by long-lived plasma cells

2009 · Morgan Taillardet, Ghina Haffar, et al. · Blood · 102

Interleukin 4 inhibits the proliferation but not the differentiation of activated human B cells in response to interleukin 2.

1988 · T Defrance, B Vanbervliet, et al. · The Journal of Experimental Medicine · 97

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Works count: 117

Citation count: 8,631

H-index: 47

I10-index: 77