Author

Zackary M. Herbst

Observed names: Z. M. Herbst, Zachary Herbst, Zackary (Ari) M. Herbst, Zackary Herbst, Zackary M Herbst

Observed institution: University of Washington

ORCID: 0000-0002-0097-4222

Observed ORCID: 0000-0002-0097-4222

OpenAlex ID: A5048965702

Urea Derivatives of 2-Aryl-benzothiazol-5-amines: A New Class of Potential Drugs for Human African Trypanosomiasis

2016 · Donald A. Patrick, J. Robert Gillespie, et al. · Journal of Medicinal Chemistry · 61

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1-Benzyl-3-aryl-2-thiohydantoin Derivatives as New Anti- Trypanosoma brucei Agents: SAR and in Vivo Efficacy

2017 · Andriy Buchynskyy, J. Robert Gillespie, et al. · ACS Medicinal Chemistry Letters · 44

Evaluation of Multiple Methods for Quantification of Glycosaminoglycan Biomarkers in Newborn Dried Blood Spots from Patients with Severe and Attenuated Mucopolysaccharidosis-I

2020 · Zackary M. Herbst, Leslie Urdaneta, et al. · International Journal of Neonatal Screening · 39

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New Class of Antitrypanosomal Agents Based on Imidazopyridines

2017 · Daniel G. Silva, J. Robert Gillespie, et al. · ACS Medicinal Chemistry Letters · 34

Evaluation of Two Methods for Quantification of Glycosaminoglycan Biomarkers in Newborn Dried Blood Spots from Patients with Severe and Attenuated Mucopolysaccharidosis Type II

2022 · Zackary M. Herbst, Leslie Urdaneta, et al. · International Journal of Neonatal Screening · 30

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Triazolopyrimidines and Imidazopyridines: Structure–Activity Relationships and in Vivo Efficacy for Trypanosomiasis

2018 · Pendem Nagendar, J. Robert Gillespie, et al. · ACS Medicinal Chemistry Letters · 25

Quantification of lysosphingomyelin and lysosphingomyelin-509 for the screening of acid sphingomyelinase deficiency

2022 · Francyne Kubaski, Alberto Burlina, et al. · Orphanet Journal of Rare Diseases · 21

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Pilot study of newborn screening for six lysosomal diseases in Brazil

2023 · Francyne Kubaski, Ines Sousa, et al. · Molecular Genetics and Metabolism · 17

Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency

2023 · Lars Schlotawa, Karolina Tyka, et al. · EMBO Molecular Medicine · 16

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Combination HSCT and intravenous AAV-mediated gene therapy in a canine model proves pivotal for translation of Krabbe disease therapy

2023 · Allison M. Bradbury, Jessica Bagel, et al. · Molecular Therapy · 15

Endogenous, non-reducing end glycosaminoglycan biomarkers are superior to internal disaccharide glycosaminoglycan biomarkers for newborn screening of mucopolysaccharidoses and GM1 gangliosidosis

2023 · Zackary M. Herbst, Xinying Hong, et al. · Molecular Genetics and Metabolism · 15

Newborn screening for the full set of mucopolysaccharidoses in dried blood spots based on first-tier enzymatic assay followed by second-tier analysis of glycosaminoglycans

2023 · Zackary M. Herbst, Xinying Hong, et al. · Molecular Genetics and Metabolism · 14

Endogenous, non-reducing end glycosaminoglycan biomarkers for the mucopolysaccharidoses: Accurate diagnosis and elimination of false positive newborn screening results

2023 · Jennifer T. Saville, Zackary M. Herbst, et al. · Molecular Genetics and Metabolism · 14

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Achieving Congruence among Reference Laboratories for Absolute Abundance Measurement of Analytes for Rare Diseases: Psychosine for Diagnosis and Prognosis of Krabbe Disease

2020 · Zackary Herbst, Coleman T. Turgeon, et al. · International Journal of Neonatal Screening · 12

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Measurement of sulfatides in the amniotic fluid supernatant: A useful tool in the prenatal diagnosis of metachromatic leukodystrophy

2022 · Francyne Kubaski, Zackary M. Herbst, et al. · JIMD Reports · 10

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Phenotypic Drug Discovery for Human African Trypanosomiasis: A Powerful Approach

2020 · Frederick S. Buckner, Andriy Buchynskyy, et al. · Tropical Medicine and Infectious Disease · 10

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Disease correction in mucopolysaccharidosis type IIIB mice by intraparenchymal or cisternal delivery of a capsid modified AAV8 codon-optimized NAGLU vector

2022 · Courtney J Rouse, Kimberley Hawkins, et al. · Human Molecular Genetics · 8

Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry Analysis of Urinary Oligosaccharides and Glycoamino Acids for the Diagnosis of Mucopolysaccharidosis and Glycoproteinosis

2024 · Parith Wongkittichote, Se Hyun Cho, et al. · Clinical Chemistry · 7

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Biochemical signatures of disease severity in multiple sulfatase deficiency

2023 · Laura A. Adang, Samar Mowafy, et al. · Journal of Inherited Metabolic Disease · 7

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High precision newborn screening for mucopolysaccharidosis type I by enzymatic activity followed by endogenous, non-reducing end glycosaminoglycan analysis

2024 · Zackary M. Herbst, Francyne Kubaski, et al. · Molecular Genetics and Metabolism · 6

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Experience of the NPC Brazil Network with a Comprehensive Program for the Screening and Diagnosis of Niemann-Pick Disease Type C

2022 · Francyne Kubaski, Alberto Burlina, et al. · International Journal of Neonatal Screening · 6

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Biochemical diagnosis of aromatic-L-amino acid decarboxylase deficiency (AADCD) by assay of AADC activity in plasma using liquid chromatography/tandem mass spectrometry

2022 · Gabriel Civallero, Francyne Kubaski, et al. · Molecular Genetics and Metabolism Reports · 6

Evaluation of 3-O-methyldopa as a biomarker for aromatic L-amino acid decarboxylase deficiency in 7 Brazilian cases

2021 · Francyne Kubaski, Zackary M. Herbst, et al. · Molecular Genetics and Metabolism Reports · 5

An Inexpensive, In-House-Made, Microdialysis Device for Measuring Drug–Protein Binding

2017 · Zackary M. Herbst, Sayaka Shibata, et al. · ACS Medicinal Chemistry Letters · 5

Analysis of serum oligosaccharides by UPLC-MS/MS for diagnosis and treatment monitoring of patients with alpha-mannosidosis

2025 · Francyne Kubaski, Allison Cason, et al. · Molecular Genetics and Metabolism · 4

Works count: 40

Citation count: 439

H-index: 13

I10-index: 16