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Nathalie Fretellier

T1-Weighted Hypersignal in the Deep Cerebellar Nuclei After Repeated Administrations of Gadolinium-Based Contrast Agents in Healthy Rats: Difference Between Linear and Macrocyclic Agents
2015 · Philippe Robert, Stéphane Lehericy, et al. · Investigative Radiology · 261
Physicochemical and Pharmacokinetic Profiles of Gadopiclenol: A New Macrocyclic Gadolinium Chelate With High T1 Relaxivity
2019 · Caroline Robic, Marc Port, et al. · Investigative Radiology · 157
The role of gadolinium chelates in the mechanism of nephrogenic systemic fibrosis: A critical update
2014 · Jean-Marc Idée, Nathalie Fretellier, et al. · Critical Reviews in Toxicology · 113
Comparative In Vivo Dissociation of Gadolinium Chelates in Renally Impaired Rats: A Relaxometry Study
2011 · Nathalie Fretellier, Jean-Marc Idée, et al. · Investigative Radiology · 63
Clinical, Biological, and Skin Histopathologic Effects of Ionic Macrocyclic and Nonionic Linear Gadolinium Chelates in a Rat Model of Nephrogenic Systemic Fibrosis
2010 · Nathalie Fretellier, Jean-Marc Idée, et al. · Investigative Radiology · 56
Gadolinium Retention, Brain T1 Hyperintensity, and Endogenous Metals: A Comparative Study of Macrocyclic Versus Linear Gadolinium Chelates in Renally Sensitized Rats
2018 · Marlène Rasschaert, Andréa Emerit, et al. · Investigative Radiology · 55
Methodological Aspects for Preclinical Evaluation of Gadolinium Presence in Brain Tissue: Critical Appraisal and Suggestions for Harmonization—A Joint Initiative
2018 · Philippe Robert, Thomas Frenzel, et al. · Investigative Radiology · 52
Moderate Renal Failure Accentuates T1 Signal Enhancement in the Deep Cerebellar Nuclei of Gadodiamide-Treated Rats
2016 · Marlène Rasschaert, Jean-Marc Idée, et al. · Investigative Radiology · 49
Total gadolinium tissue deposition and skin structural findings following the administration of structurally different gadolinium chelates in healthy and ovariectomized female rats.
2015 · Yì-Xiáng J Wáng, Joseph Schroeder, et al. · Europe PMC (PubMed Central) · 47
Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues? A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats
2018 · Nathalie Fretellier, Agnès Granottier, et al. · Investigative Radiology · 44
Multimodal Imaging Study of Gadolinium Presence in Rat Cerebellum: Differences Between Gd Chelates, Presence in the Virchow-Robin Space, Association With Lipofuscin, and Hypotheses About Distribution Pathway
2018 · Marlène Rasschaert, Josef A. Schroeder, et al. · Investigative Radiology · 40
Nephrogenic Systemic Fibrosis-Like Effects of Magnetic Resonance Imaging Contrast Agents in Rats with Adenine-Induced Renal Failure
2012 · Nathalie Fretellier, Nejma Bouzian, et al. · Toxicological Sciences · 25
Gadolinium Contrast Agent Associated Stimulation of Human Fibroblast Collagen Production
2011 · Sheila MacNeil, Sarah Bains, et al. · Investigative Radiology · 23
Preclinical Safety Assessment of Gadopiclenol: A High-Relaxivity Macrocyclic Gadolinium-Based MRI Contrast Agent
2023 · Célia Gendron, Philippe Bourrinet, et al. · Investigative Radiology · 22
Hyperphosphataemia sensitizes renally impaired rats to the profibrotic effects of gadodiamide
2011 · N Fretellier, JM Idée, et al. · British Journal of Pharmacology · 22
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Non-clinical safety assessment of gadoterate meglumine (Dotarem®) in neonatal and juvenile rats
2015 · Hervé Giorgi, Jennifer Ammerman, et al. · Regulatory Toxicology and Pharmacology · 21
Safety and Gadolinium Distribution of the New High-Relaxivity Gadolinium Chelate Gadopiclenol in a Rat Model of Severe Renal Failure
2021 · Nathalie Fretellier, Marlène Rasschaert, et al. · Investigative Radiology · 16
Distribution profile of gadolinium in gadolinium chelate-treated renally-impaired rats: Role of pharmaceutical formulation
2015 · Nathalie Fretellier, Mariem Salhi, et al. · European Journal of Pharmaceutical Sciences · 16
Analytical Interference in Serum Iron Determination Reveals Iron Versus Gadolinium Transmetallation With Linear Gadolinium-Based Contrast Agents
2014 · Nathalie Fretellier, Nathalie Poteau, et al. · Investigative Radiology · 13
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Overall Gadolinium Exposure Within the First 5 Months After Injection of Human Equivalent Doses of Gadopiclenol, Gadoterate, or Gadobutrol in Healthy Rats
2025 · Marlène Rasschaert, Emilie Couloumy, et al. · Investigative Radiology · 12
Physico-chimie et profil toxicologique d’agents de contraste pour l’imagerie par résonance magnétique, les chélates de gadolinium
2015 · J.-M. Idée, N. Fretellier, et al. · Annales Pharmaceutiques Françaises · 11
Gadolinium Deposition in Bone Tissues After Contrast-enhanced Magnetic Resonance Imaging: A Comprehensive Review
2025 · Nathalie Fretellier, Jean-Marc Idée, et al. · Investigative Radiology · 9
Safety profiles of gadolinium chelates in juvenile rats differ according to the risk of dissociation
2014 · Nathalie Fretellier, Meryam Maazouz, et al. · Reproductive Toxicology · 8
Region of Interest Selection in Nonclinical Studies of Accumulated Gadolinium-based Contrast Agent–induced T1 Hyperintensity in Deep Cerebellar Nuclei
2018 · Jean-Marc Idée, Philippe Robert, et al. · Radiology · 5
Evaluation of gadolinium‐based contrast agents in pregnant CD ‐1 mice and subsequent in utero exposure of the developing offspring, including behavioral evaluations
2023 · Elise M. Lewis, Simona Bussi, et al. · Birth Defects Research · 4
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Works count: 33
Citation count: 1,151
H-index: 16
I10-index: 21
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