Get started
Author

Okechukwu T. Ukairo

Observed names: Okechukwu T Ukairo, Okechukwu Ukairo, Okechukwu Ukairo Dustin R Berger Brenton R Ware Michael McVay
Observed institutions: Merck & Co., Inc., Rahway, NJ, USA (United States), Duquesne University, University of Massachusetts Chan Medical School, Pfizer (United States), Bristol-Myers Squibb (United States), Agios Pharmaceuticals (United States), Medtronic (United Kingdom), Ipsen (United States), BioIVT (United States), Colorado State University
ORCID: 0000-0002-1785-7663
Observed ORCID: 0000-0002-1785-7663
OpenAlex ID: A5049284371
Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans
2012 · Salman R. Khetani, Chitra Kanchagar, et al. · Toxicological Sciences · 218
Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
2015 · Theresa V Nguyen, Okechukwu Ukairo, et al. · Drug Metabolism and Disposition · 138
Long‐Term Stability of Primary Rat Hepatocytes in Micropatterned Cocultures
2013 · Okechukwu Ukairo, Chitra Kanchagar, et al. · Journal of Biochemical and Molecular Toxicology · 62
Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans
2016 · Franck A. Atienzar, Eric A. Blomme, et al. · BioMed Research International · 60
PDF
Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism
2015 · T. Eric Ballard, Shuai Wang, et al. · Drug Metabolism and Disposition · 53
Recognition of Benztropine by the Dopamine Transporter (DAT) Differs from That of the Classical Dopamine Uptake Inhibitors Cocaine, Methylphenidate, and Mazindol as a Function of a DAT Transmembrane 1 Aspartic Acid Residue
2005 · Okechukwu T. Ukairo, Corry D. Bondi, et al. · Journal of Pharmacology and Experimental Therapeutics · 47
Critical role for apoptosis signal-regulating kinase 1 in the development of inflammatory K/BxN serum-induced arthritis
2010 · Stephen J. Mnich, Patrick M. Blanner, et al. · International Immunopharmacology · 38
Recognition of psychostimulants, antidepressants, and other inhibitors of synaptic neurotransmitter uptake by the plasma membrane monoamine transporters
2005 · Christopher K. Surratt, Okechukwu T. Ukairo, et al. · The AAPS Journal · 26
Dissociation of High-Affinity Cocaine Analog Binding and Dopamine Uptake Inhibition at the Dopamine Transporter
2003 · Wenfei Wang, Mark S Sonders, et al. · Molecular Pharmacology · 21
Fluctuation of the dopamine uptake inhibition potency of cocaine, but not amphetamine, at mammalian cells expressing the dopamine transporter
2006 · Okechukwu T. Ukairo, Suneetha Ramanujapuram, et al. · Brain Research · 12
Bioactivation and Toxicity of Acetaminophen in a Rat Hepatocyte Micropatterned Coculture System
2013 · Okechukwu Ukairo, Michael McVay, et al. · Journal of Biochemical and Molecular Toxicology · 10
Liver safety evaluation of endothelin receptor antagonists using HepatoPac®: A single model impact assessment on hepatocellular health, function and bile acid disposition
2019 · Michael D. Aleo, Okechukwu Ukairo, et al. · Journal of Applied Toxicology · 9
Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity
2025 · Sayumi Yamazoe, Yam Poudel, et al. · Journal of Medicinal Chemistry · 5
PDF
In vitro modeling of cytokine–drug interactions using micropatterned co-cultures of primary hepatocytes and Kupffer macrophages
2013 · Michael McVay, Chitra Kanchagar, et al. · Toxicology Letters · 2
Nuclear Receptor-Mediated Gene Expression Changes in a Human Hepatic Micropatterned Coculture Model After Treatment with Hepatotoxic Compounds
2016 · Kelly Rose, Kristina K. Wolf, et al. · Applied In Vitro Toxicology · 1
Fluctuation of the dopamine uptake inhibition potency of cocaine, but not amphetamine, in CHO cells stably transfected with the dopamine transporter
2006 · Suneetha Ramanujapuram, Okechukwu T Ukairo, et al. · The FASEB Journal · 1
Exploring chronic drug dosing in engineered human liver cultures using global expression profiling
2015 · Okechukwu Ukairo Dustin R Berger Brenton R Ware Michael McVay, Salman R. Khetani · Journal of Drug Metabolism & Toxicology
Toxicity of selected bioactivated compounds in primary rat hepatocytes cultured in micropatterned co-cultures
2014 · Okechukwu Ukairo, Julianne Shi, et al. · Toxicology Letters
Recognition of Psychostimulants, Antidepressants, and Other Inhibitors of Synaptic Neurotransmitter Uptake by the Plasma Membrane Monoamine Transporters
2008 · Christopher K. Surratt, Okechukwu T. Ukairo, et al. · Springer eBooks
Structural Determinants for Substrate and Inhibitor Recognition by the Dopamine Transporter
2005 · Okechukwu Ukairo
Works count: 20
Citation count: 703
H-index: 10
I10-index: 11
Year
Topic
Type