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Philippe Mellet

Alkoxyamines: a new family of pro-drugs against cancer. Concept for theranostics
2013 · Gérard Audran, Paul Brémond, et al. · Organic & Biomolecular Chemistry · 56
New Concepts in Molecular Imaging: Non-Invasive MRI Spotting of Proteolysis Using an Overhauser Effect Switch
2009 · Philippe Mellet, Philippe Massot, et al. · PLoS ONE · 55
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Alkoxyamines: Toward a New Family of Theranostic Agents against Cancer
2014 · Damien Moncelet, Pierre Voisin, et al. · Molecular Pharmaceutics · 48
In vivo high‐resolution 3D Overhauser‐enhanced MRI in mice at 0.2 T
2012 · Philippe Massot, Elodie Parzy, et al. · Contrast Media & Molecular Imaging · 40
Enzymatically Shifting Nitroxides for EPR Spectroscopy and Overhauser‐Enhanced Magnetic Resonance Imaging
2015 · Gérard Audran, Lionel Bosco, et al. · Angewandte Chemie International Edition · 39
In vivo Overhauser‐enhanced MRI of proteolytic activity
2014 · Neha Koonjoo, Elodie Parzy, et al. · Contrast Media & Molecular Imaging · 38
Smart Alkoxyamines: A New Tool for Smart Applications
2020 · Gérard Audran, Sylvain R. A. Marque, et al. · Accounts of Chemical Research · 37
DNA Strongly Impairs the Inhibition of Cathepsin G by α1-Antichymotrypsin and α1-Proteinase Inhibitor
2000 · Jérôme Duranton, Christian Boudier, et al. · Journal of Biological Chemistry · 34
Stopped Flow Fluorescence Energy Transfer Measurement of the Rate Constants Describing the Reversible Formation and the Irreversible Rearrangement of the Elastase-α1-Proteinase Inhibitor Complex
1998 · Philippe Mellet, Christian Boudier, et al. · Journal of Biological Chemistry · 32
An elastase activity reporter for Electronic Paramagnetic Resonance (EPR) and Overhauser-enhanced Magnetic Resonance Imaging (OMRI) as a line-shifting nitroxide
2018 · Natacha Jugniot, Indranil Duttagupta, et al. · Free Radical Biology and Medicine · 26
Overhauser-Enhanced MRI of Elastase Activity from In Vitro Human Neutrophil Degranulation
2013 · Elodie Parzy, Véronique Bouchaud, et al. · PLoS ONE · 26
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Dynamic Covalent Bond: Modes of Activation of the C—ON Bond in Alkoxyamines
2023 · Gérard Audran, Elena G. Bagryanskaya, et al. · Progress in Polymer Science · 24
Heat-induced Conversion of Ovalbumin into a Proteinase Inhibitor
1996 · Philippe Mellet, Bernard Michels, et al. · Journal of Biological Chemistry · 24
Evidence That Translocation of the Proteinase Precedes Its Acylation in the Serpin Inhibition Pathway
2000 · Philippe Mellet, Joseph G. Bieth · Journal of Biological Chemistry · 22
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Enzymatic triggering of C–ON bond homolysis of alkoxyamines
2019 · Gérard Audran, Lionel Bosco, et al. · Organic Chemistry Frontiers · 21
Cellular Density Effect on RGD Ligand Internalization in Glioblastoma for MRI Application
2013 · Damien Moncelet, Véronique Bouchaud, et al. · PLoS ONE · 19
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Neutrophil Elastase Activity Imaging: Recent Approaches in the Design and Applications of Activity-Based Probes and Substrate-Based Probes
2019 · Natacha Jugniot, Pierre Voisin, et al. · Contrast Media & Molecular Imaging · 16
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Mapping the Heparin-Binding Site of Mucus Proteinase Inhibitor
1995 · Philippe Mellet, Jacques Ermolieff, et al. · Biochemistry · 16
Neutrophil Elastase-Activatable Prodrugs Based on an Alkoxyamine Platform to Deliver Alkyl Radicals Cytotoxic to Tumor Cells
2022 · Seda Seren, Jean-Patrick Joly, et al. · Journal of Medicinal Chemistry · 15
An enzymatic acetal/hemiacetal conversion for the physiological temperature activation of the alkoxyamine C–ON bond homolysis
2020 · Muriel Albalat, Gérard Audran, et al. · Organic Chemistry Frontiers · 15
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Selective On/Off‐Nitroxides as Radical Probes to Investigate Non‐radical Enzymatic Activity by Electron Paramagnetic Resonance
2018 · Indranil Duttagupta, Natacha Jugniot, et al. · Chemistry - A European Journal · 14
Nitrite tryptophan reaction: evidence for an equilibrium between tryptophan and its nitrosated form
1986 · Philippe O. Mellet, Patrick R. Noel, et al. · Journal of Agricultural and Food Chemistry · 13
Hybrid Peptide-Alkoxyamine Drugs: A Strategy for the Development of a New Family of Antiplasmodial Drugs
2024 · Ange W. Embo-Ibouanga, Michel Nguyen, et al. · Molecules · 11
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The β-phosphorus hyperfine coupling constant in nitroxide: part 3: titration of water by electron paramagnetic resonance
2015 · Gérard Audran, Lionel Bosco, et al. · Organic & Biomolecular Chemistry · 10
β-Phosphorus hyperfine coupling constant in nitroxides: 5. Solvent effect
2016 · Gérard Audran, Lionel Bosco, et al. · RSC Advances · 9
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Works count: 67
Citation count: 757
H-index: 16
I10-index: 24
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