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Thimo Kurz
Observed names:
Kurz Thimo,
Kurz, Thimo,
T. Kurz
Institutions:
Evotec (United Kingdom),
University of Glasgow
Observed institutions:
University of Dundee,
University of Oregon,
ETH Zurich,
MRC Protein Phosphorylation and Ubiquitylation Unit,
Evotec (United Kingdom),
Institute of Biochemistry,
University of Glasgow,
Medical Research Council
show all 8
ORCID:
0000-0003-0700-6993
Observed ORCID:
0000-0003-0700-6993
OpenAlex ID:
A5049577833
The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase
2003
·
Lionel Pintard
, John H. Willis
, et al.
·
Nature
·
435
UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome
2016
·
Roland Hjerpe
, John S. Bett
, et al.
·
Cell
·
308
PDF
The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction
2013
·
Akihito Ohta
, Frances-Rose Schumacher
, et al.
·
Biochemical Journal
·
226
PDF
Cytoskeletal Regulation by the Nedd8 Ubiquitin-Like Protein Modification Pathway
2002
·
Thimo Kurz
, Lionel Pintard
, et al.
·
Science
·
207
Dcn1 Functions as a Scaffold-Type E3 Ligase for Cullin Neddylation
2008
·
Thimo Kurz
, Yang-Chieh Chou
, et al.
·
Molecular Cell
·
200
PDF
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae
2005
·
Thimo Kurz
, Nurhan Özlü
, et al.
·
Nature
·
188
Neddylation and Deneddylation of CUL-3 Is Required to Target MEI-1/Katanin for Degradation at the Meiosis-to-Mitosis Transition in C. elegans
2003
·
Lionel Pintard
, Thimo Kurz
, et al.
·
Current Biology
·
182
PDF
Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes
2011
·
Roland Hjerpe
, Yann Thomas
, et al.
·
Biochemical Journal
·
109
PDF
Characterisation of the Cullin‐3 mutation that causes a severe form of familial hypertension and hyperkalaemia
2015
·
Frances‐Rose Schumacher
, Keith Siew
, et al.
·
EMBO Molecular Medicine
·
104
PDF
CSN- and CAND1-dependent remodelling of the budding yeast SCF complex
2013
·
Aleksandra Zemla
, Yann Thomas
, et al.
·
Nature Communications
·
102
PDF
A Dual E3 Mechanism for Rub1 Ligation to Cdc53
2010
·
Daniel C. Scott
, Julie K. Monda
, et al.
·
Molecular Cell
·
102
PDF
The Cullin Rtt101p Promotes Replication Fork Progression through Damaged DNA and Natural Pause Sites
2006
·
Brian Luke
, Gwennaelle Versini
, et al.
·
Current Biology
·
93
PDF
The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes
2009
·
Nathalie Meyer-Schaller
, Yang-Chieh Chou
, et al.
·
Proceedings of the National Academy of Sciences
·
91
Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulation
2014
·
Frances-Rose Schumacher
, Fiona J. Sorrell
, et al.
·
Biochemical Journal
·
79
PDF
Degrade to create: developmental requirements for ubiquitin-mediated proteolysis during earlyC. elegansembryogenesis
2006
·
Bruce Bowerman
, Thimo Kurz
·
Development
·
78
WNK signalling pathways in blood pressure regulation
2016
·
Meena Murthy
, Thimo Kurz
, et al.
·
Cellular and Molecular Life Sciences
·
57
PDF
Altered ubiquitin signaling induces Alzheimer’s disease-like hallmarks in a three-dimensional human neural cell culture model
2023
·
Inbal Maniv
, Mahasen Sarji
, et al.
·
Nature Communications
·
54
PDF
Characterization of the mammalian family of DCN-type NEDD8 E3 ligases
2016
·
Matthew J. Keuss
, Yann Thomas
, et al.
·
Journal of Cell Science
·
54
PDF
Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers
2014
·
John S. Bett
, Maria Stella Ritorto
, et al.
·
Biochemical Journal
·
53
The TFIIH Subunit Tfb3 Regulates Cullin Neddylation
2011
·
Gwenaël Rabut
, Gaëlle Le Dez
, et al.
·
Molecular Cell
·
53
PDF
Global proteomics of Ubqln2-based murine models of ALS
2020
·
Alexandra M. Whiteley
, Miguel A. Prado
, et al.
·
Journal of Biological Chemistry
·
52
NEDD8 Overexpression Results in Neddylation of Ubiquitin Substrates by the Ubiquitin Pathway
2012
·
Roland Hjerpe
, Yann Thomas
, et al.
·
Journal of Molecular Biology
·
51
PDF
Unanchored tri‐NEDD8 inhibits PARP‐1 to protect from oxidative stress‐induced cell death
2019
·
Matthew J Keuss
, Roland Hjerpe
, et al.
·
The EMBO Journal
·
47
PDF
The COP9 signalosome is vital for timely repair of DNA double-strand breaks
2015
·
Michal Meir
, Yaron Galanty
, et al.
·
Nucleic Acids Research
·
46
PDF
Cullin neddylation and substrate‐adaptors counteract SCF inhibition by the CAND1‐like protein Lag2 in Saccharomyces cerevisiae
2009
·
Edyta Siergiejuk
, Daniel C Scott
, et al.
·
The EMBO Journal
·
35
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Works count:
36
Citation count:
3,063
H-index:
25
I10-index:
29
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