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Karin M. J. Koolen

Observed names: K. M. J. Koolen, Karin J. M. Koolen, Karin J.M. Koolen, Karin M. Koolen, Karin M.J. Koolen, Karin MJ Koolen, Koolen, Karin MJ
Observed institution: TropIQ Health Sciences
ORCID: 0000-0003-2464-7215
Observed ORCID: 0000-0003-2464-7215
OpenAlex ID: A5049839078
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors
2016 · Nobutaka Kato, Eamon Comer, et al. · Nature · 258
Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases
2018 · Marie Miglianico, Maarten Eldering, et al. · Proceedings of the National Academy of Sciences · 101
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Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum
2019 · Joost Schalkwijk, Erik L. Allman, et al. · Science Translational Medicine · 86
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A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes
2015 · Martijn W. Vos, Will J. R. Stone, et al. · Scientific Reports · 75
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A combination of new screening assays for prioritization of transmission-blocking antimalarials reveals distinct dynamics of marketed and experimental drugs
2015 · J. M. Bolscher, K. M. J. Koolen, et al. · Journal of Antimicrobial Chemotherapy · 53
Salinomycin and Other Ionophores as a New Class of Antimalarial Drugs with Transmission-Blocking Activity
2015 · Sarah D'Alessandro, Yolanda Corbett, et al. · Antimicrobial Agents and Chemotherapy · 52
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Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues
2018 · Alessandra Vallone, Sarah D'Alessandro, et al. · European Journal of Medicinal Chemistry · 46
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An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines
2016 · Kazutoyo Miura, Will J. R. Stone, et al. · Malaria Journal · 46
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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183
2022 · Laura E. de Vries, Patrick A. M. Jansen, et al. · Nature Communications · 40
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Novel pantothenate derivatives for anti-malarial chemotherapy
2015 · Helmi E Pett, Patrick AM Jansen, et al. · Malaria Journal · 25
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Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission
2017 · Koen J. Dechering, Hans-Peter Duerr, et al. · Scientific Reports · 24
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A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages
2019 · Catherin Marin-Mogollon, Ahmed M. Salman, et al. · Frontiers in Cellular and Infection Microbiology · 22
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Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out
2022 · Koen J. Dechering, Martijn Timmerman, et al. · SLAS DISCOVERY · 18
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Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening
2023 · Marie Miglianico, Judith M. Bolscher, et al. · Communications Biology · 12
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A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo
2024 · Stanley C. Xie, Chia-Wei Tai, et al. · PLoS Pathogens · 5
Barcoded Asaia bacteria enable mosquito in vivo screens and identify novel systemic insecticides and inhibitors of malaria transmission
2021 · Angelika Sturm, Martijn W. Vos, et al. · PLoS Biology · 3
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Author Correction: Diversity-oriented synthesis yields novel multistage antimalarial inhibitors
2025 · Nobutaka Kato, Eamon Comer, et al. · Nature
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CCDC 1429949: Experimental Crystal Structure Determination
2016 · Kato, Nobutaka, Comer, Eamon, et al. · The Cambridge Structural Database
Works count: 18
Citation count: 866
H-index: 13
I10-index: 14
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