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Karen Olivia Dixon
Observed names:
K. Dixon,
Karen Dixon,
Karen O Dixon,
Karen O. Dixon
Institutions:
Brigham and Women's Hospital,
Harvard University,
University of Basel,
Massachusetts General Hospital
Observed institutions:
Broad Institute,
Brigham and Women's Hospital,
Harvard University,
University of Basel,
Leiden University Medical Center,
University Hospital of Basel,
Massachusetts General Hospital,
Klarman Cell Observatory,
Mass General Brigham
show all 9
ORCID:
0000-0001-7811-5439
Observed ORCID:
0000-0001-7811-5439
OpenAlex ID:
A5050026428
Works
37
Awards
6
TIM-3 restrains anti-tumour immunity by regulating inflammasome activation
2021
·
Karen O. Dixon
, Marcin Tabaka
, et al.
·
Nature
·
394
Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
2020
·
Nandini Acharya
, Asaf Madi
, et al.
·
Immunity
·
264
Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity
2018
·
Karen O Dixon
, Michelle Schorer
, et al.
·
The Journal of Immunology
·
169
Neuro-immune cross-talk in cancer
2025
·
Moran Amit
, Tuany Eichwald
, et al.
·
Nature reviews. Cancer
·
139
Human tolerogenic dendritic cells produce IL‐35 in the absence of other IL‐12 family members
2015
·
Karen O. Dixon
, Sandra W. van der Kooij
, et al.
·
European Journal of Immunology
·
110
PDF
Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease
2025
·
Kimitoshi Kimura
, Ayshwarya Subramanian
, et al.
·
Nature
·
89
Beyond T cell exhaustion: TIM-3 regulation of myeloid cells
2024
·
Karen O. Dixon
, Gonzalo Fernandez Lahore
, et al.
·
Science Immunology
·
89
Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function
2022
·
Ruihan Tang
, Nandini Acharya
, et al.
·
Science Immunology
·
59
Myeloperoxidase Directs Properdin-Mediated Complement Activation
2013
·
Joseph O'Flynn
, Karen O. Dixon
, et al.
·
Journal of Innate Immunity
·
55
PDF
Next Directions in the Neuroscience of Cancers Arising outside the CNS
2024
·
Moran Amit
, Corina Anastasaki
, et al.
·
Cancer Discovery
·
50
PDF
Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion
2021
·
Chen Zhu
, Karen O. Dixon
, et al.
·
Science Advances
·
45
Transcription factor TCF1 binds to RORγt and orchestrates a regulatory network that determines homeostatic Th17 cell state
2024
·
Davide Mangani
, Ayshwarya Subramanian
, et al.
·
Immunity
·
38
Properdin and factor H production by human dendritic cells modulates their T‐cell stimulatory capacity and is regulated by IFN‐γ
2017
·
Karen O. Dixon
, Joseph O'Flynn
, et al.
·
European Journal of Immunology
·
37
PDF
Entangled cellular and molecular relationships at the sensory neuron-cancer interface
2025
·
Debpali Sur
, Yi Zeng
, et al.
·
Neuron
·
34
Oncogene-induced TIM-3 ligand expression dictates susceptibility to anti–TIM-3 therapy in mice
2024
·
Nana Talvard-Balland
, Lukas M. Braun
, et al.
·
Journal of Clinical Investigation
·
29
Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity
2023
·
Laura Fernandez-Rodriguez
, Chiara Cianciaruso
, et al.
·
Journal for ImmunoTherapy of Cancer
·
28
PDF
Monomeric C-reactive protein inhibits renal cell-directed complement activation mediated by properdin
2016
·
Joseph O'Flynn
, Pieter van der Pol
, et al.
·
American Journal of Physiology-Renal Physiology
·
22
IL-18: throwing off the shackles to boost anti-tumor immunity
2020
·
Karen O. Dixon
, Vijay K. Kuchroo
·
Cell Research
·
21
PDF
Human disease mutations highlight the inhibitory function of TIM-3
2018
·
Karen O. Dixon
, Madhumita Das
, et al.
·
Nature Genetics
·
19
Phagocytosis of apoptotic or necrotic cells differentially regulates the transcriptional expression of IL-12 family members in dendritic cells
2014
·
Karen O Dixon
, Joseph O'Flynn
, et al.
·
Journal of Leukocyte Biology
·
19
Next-gen tools in cancer neuroscience
2025
·
Vera Thiel
, Debpali Sur
, et al.
·
Cell Reports
·
18
PDF
Human renal fibroblasts generate dendritic cells with a unique regulatory profile
2014
·
Karen O Dixon
, Laura Rossmann
, et al.
·
Immunology and Cell Biology
·
10
The Dorsal Root Ganglia: From a Neuronal Relay to a Sensory Organ
2026
·
Anais Roger
, Linda Kaupp
, et al.
·
Annual Review of Neuroscience
·
4
InTraSeq: A Multimodal Assay that Uncovers New Single-Cell Biology and Regulatory Mechanisms
2024
·
Sean Beausoleil
, Majd Ariss
, et al.
·
Research Square
·
3
PDF
Entangled cellular and molecular relationships at the sensory neuron-cancer interface
2025
·
Debpali Sur
, Yi Zeng
, et al.
·
Neuron
·
2
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Works count:
37
Citation count:
1,757
H-index:
19
I10-index:
22
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