Get started
Author

Cristina Paulino

Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM
2017 · Cristina Paulino, Valeria Kalienkova, et al. · Nature · 296
PDF
Structure of a volume-regulated anion channel of the LRRC8 family
2018 · Dawid Deneka, Marta Sawicka, et al. · Nature · 198
Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
2017 · Cristina Paulino, Yvonne Neldner, et al. · eLife · 167
Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F
2019 · Carolina Alvadia, Novandy K. Lim, et al. · eLife · 158
AI is a viable alternative to high throughput screening: a 318-target study
2024 · The Atomwise AIMS Program, Izhar Wallach, et al. · Scientific Reports · 149
Cryo-EM structure of the human neutral amino acid transporter ASCT2
2018 · Alisa A. Garaeva, Gert T. Oostergetel, et al. · Nature Structural & Molecular Biology · 133
Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM
2019 · Valeria Kalienkova, Vanessa Clerico Mosina, et al. · eLife · 116
The Groovy TMEM16 Family: Molecular Mechanisms of Lipid Scrambling and Ion Conduction
2021 · Valeria Kalienkova, Vanessa Clerico Mosina, et al. · Journal of Molecular Biology · 105
PDF
A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2
2019 · Alisa A. Garaeva, Albert Guskov, et al. · Nature Communications · 101
PDF
Structure and transport mechanism of the sodium/proton antiporter MjNhaP1
2014 · Cristina Paulino, David Wöhlert, et al. · eLife · 92
Structural basis for the activation of the lipid scramblase TMEM16F
2022 · Melanie Arndt, Carolina Alvadia, et al. · Nature Communications · 61
PDF
Structure of the archaeal Na+/H+ antiporter NhaP1 and functional role of transmembrane helix 1
2010 · Panchali Goswami, Cristina Paulino, et al. · The EMBO Journal · 60
Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA
2020 · Hendrik R. Sikkema, Marco van den Noort, et al. · Science Advances · 59
PDF
Gating the pore of the calcium-activated chloride channel TMEM16A
2021 · Andy K. M. Lam, Jan Rheinberger, et al. · Nature Communications · 58
PDF
Rational design of ASCT2 inhibitors using an integrated experimental-computational approach
2021 · Rachel-Ann A. Garibsingh, Elias Ndaru, et al. · Proceedings of the National Academy of Sciences · 55
PDF
Biparatopic sybodies neutralize SARS‐CoV‐2 variants of concern and mitigate drug resistance
2022 · Justin D. Walter, Cedric A.J. Hutter, et al. · EMBO Reports · 49
PDF
Cryo-EM structures of KdpFABC suggest a K+ transport mechanism via two inter-subunit half-channels
2018 · C. Stock, L. Hielkema, et al. · Nature Communications · 49
PDF
Keeping It Simple, Transport Mechanism and pH Regulation in Na+/H+ Exchangers
2014 · Octavian Călinescu, Cristina Paulino, et al. · Journal of Biological Chemistry · 46
PDF
Optimized cryo-EM data-acquisition workflow by sample-thickness determination
2021 · Jan Rheinberger, Gert Oostergetel, et al. · Acta Crystallographica Section D Structural Biology · 35
PDF
pH- and sodium-induced changes in a sodium/proton antiporter
2014 · Cristina Paulino, Werner Kühlbrandt · eLife · 32
Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
2021 · Jakob M. Silberberg, Robin A. Corey, et al. · Nature Communications · 24
PDF
Structures of a sperm-specific solute carrier gated by voltage and cAMP
2023 · Valeria Kalienkova, Martin F. Peter, et al. · Nature · 21
PDF
Inhibited KdpFABC transitions into an E1 off-cycle state
2022 · Jakob M. Silberberg, Charlott Stock, et al. · eLife · 21
Expulsion mechanism of the substrate-translocating subunit in ECF transporters
2023 · Chancievan Thangaratnarajah, Mark Nijland, et al. · Nature Communications · 19
PDF
Cryo-EM studies of membrane proteins at 200 keV
2022 · Chancievan Thangaratnarajah, Jan Rheinberger, et al. · Current Opinion in Structural Biology · 17
PDF
Works count: 92
Citation count: 2,205
H-index: 21
I10-index: 28
Year
Topic
Type