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Firas Fadel

The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal Transduction System with the GacS/GacA Two-Component System in Pseudomonas aeruginosa
2016 · Gaël Chambonnier, Lorène Roux, et al. · PLoS Genetics · 149
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Substrate binding mode and catalytic mechanism of human heparan sulfate d -glucuronyl C5 epimerase
2019 · Claire Debarnot, Yoan R. Monneau, et al. · Proceedings of the National Academy of Sciences · 49
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X-Ray Crystal Structure of the Full Length Human Chitotriosidase (CHIT1) Reveals Features of Its Chitin Binding Domain
2016 · Firas Fadel, Yuguang Zhao, et al. · PLoS ONE · 40
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High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP–oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution
2016 · E. I. Howard, B. Guillot, et al. · IUCrJ · 40
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Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma
2017 · Marzena Mazur, Jacek Olczak, et al. · Journal of Medicinal Chemistry · 35
Structural and functional insights into the periplasmic detector domain of the GacS histidine kinase controlling biofilm formation in Pseudomonas aeruginosa
2017 · Ahmad Ali-Ahmad, Firas Fadel, et al. · Scientific Reports · 33
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New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM
2015 · Firas Fadel, Yuguang Zhao, et al. · Acta Crystallographica Section D Biological Crystallography · 31
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Structural features discriminating hybrid histidine kinase Rec domains from response regulator homologs
2023 · Mitchell Brüderlin, Raphael Böhm, et al. · Nature Communications · 13
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Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS
2022 · Firas Fadel, Violla Bassim, et al. · Structure · 13
Digital control of c-di-GMP in E. coli balances population-wide developmental transitions and phage sensitivity
2021 · Alberto Reinders, Benjamin Sellner, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5
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Engineering infrared light detection in blind human retina using ultrasensitive human TRPV1 channels
2025 · Morgan Chevalier, Firas Fadel, et al. · Trends in biotechnology · 3
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NMR assignments of the GacS histidine-kinase periplasmic detection domain from Pseudomonas aeruginosa PAO1
2016 · Ahmad Ali-Ahmad, Olivier Bornet, et al. · Biomolecular NMR Assignments · 3
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Structure of human D-glucuronyl C5 epimerase
2018 · C. Debarnot, Y.R. Monneau, et al. · Worldwide Protein Data Bank · 1
Structure of human D-glucuronyl C5 epimerase in complex with product
2018 · C. Debarnot, Y.R. Monneau, et al. · Worldwide Protein Data Bank · 1
Structure of human D-glucuronyl C5 epimerase in complex with substrate
2018 · C. Debarnot, Y.R. Monneau, et al. · Worldwide Protein Data Bank · 1
Crystal structure of human full-length chitotriosidase (CHIT1)
2015 · F. Fadel, Y. Zhao, et al. · Worldwide Protein Data Bank · 1
Crystal structure of GacS D1 domain in complex with BeF3-
2022 · F. Fadel, V. Bassim, et al. · Worldwide Protein Data Bank
Structural insights into the periplasmic sensor domain of the GacS histidine kinase controlling biofilm formation in Pseudomonas aeruginosa
2017 · A. Ali-Ahmad, O. Bornet, et al. · Worldwide Protein Data Bank
High resolution neutron and X-ray diffraction RT studies of an H-FABP – Oleic acid complex: study of the internal water cluster and the ligand binding by a transferred multipolar electron density distribution
2016 · Alberto Podjarny, Eduardo I. Howard, et al. · Acta Crystallographica Section A Foundations and Advances
Etude structurale et mécanistique à haute résolution de la chitotriosidase humaine (CHIT1)
2014 · Firas Fadel · theses.fr (ABES)
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Crystal structure of human chitotriosidase-1 catalytic domain at 1.0 A resolution
2014 · F. Fadel, Y. Zhao, et al. · Worldwide Protein Data Bank
Structural and mechanistic studies of human chitinase
2014 · Firas Fadel, Yuguang Zhao, et al. · Acta Crystallographica Section A Foundations and Advances
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Works count: 31
Citation count: 418
H-index: 9
I10-index: 9
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