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Giuliana Fusco
Observed name:
Fusco, Giuliana
Institutions:
Centro Interuniversitario di Ricerca sui Peptidi Bioattivi,
University of Naples Federico II
Observed institutions:
University of Cambridge,
Centro Interuniversitario di Ricerca sui Peptidi Bioattivi,
Imperial College London,
University of Naples Federico II
ORCID:
0000-0002-3644-9809
Observed ORCID:
0000-0002-3644-9809
OpenAlex ID:
A5050837148
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
2017
·
Giuliana Fusco
, Serene W. Chen
, et al.
·
Science
·
680
PDF
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour
2014
·
Giuliana Fusco
, Alfonso De Simone
, et al.
·
Nature Communications
·
496
PDF
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction
2018
·
Janin Lautenschläger
, Amberley D. Stephens
, et al.
·
Nature Communications
·
342
PDF
Structural basis of synaptic vesicle assembly promoted by α-synuclein
2016
·
Giuliana Fusco
, Tillmann Pape
, et al.
·
Nature Communications
·
261
PDF
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity
2020
·
Amberley D. Stephens
, Maria Zacharopoulou
, et al.
·
Nature Communications
·
166
PDF
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition
2021
·
Wing K. Man
, Bogachan Tahirbegi
, et al.
·
Nature Communications
·
117
PDF
Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity
2016
·
Giuliana Fusco
, Alfonso De Simone
, et al.
·
Scientific Reports
·
108
PDF
The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State
2020
·
Matteo Runfola
, Alfonso De Simone
, et al.
·
Scientific Reports
·
79
PDF
Membrane Interactions and Toxicity by Misfolded Protein Oligomers
2021
·
Mario Gonzalez-Garcia
, Giuliana Fusco
, et al.
·
Frontiers in Cell and Developmental Biology
·
76
PDF
Order and disorder in the physiological membrane binding of α-synuclein
2017
·
Giuliana Fusco
, Maximo Sanz-Hernandez
, et al.
·
Current Opinion in Structural Biology
·
65
Conformational Recognition of an Intrinsically Disordered Protein
2014
·
James M. Krieger
, Giuliana Fusco
, et al.
·
Biophysical Journal
·
57
PDF
Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species
2017
·
Francesco A. Aprile
, Paolo Arosio
, et al.
·
Biochemistry
·
55
The Toxicity of Misfolded Protein Oligomers Is Independent of Their Secondary Structure
2019
·
Mirella Vivoli Vega
, Roberta Cascella
, et al.
·
ACS Chemical Biology
·
53
Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies
2019
·
Roberta Cascella
, Michele Perni
, et al.
·
ACS Chemical Biology
·
51
Structure–Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates
2024
·
Serene W. Chen
, Joseph D. Barritt
, et al.
·
Journal of the American Chemical Society
·
49
PDF
A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles
2020
·
Wing K. Man
, Alfonso De Simone
, et al.
·
Frontiers in Neuroscience
·
45
PDF
Molecular determinants of the interaction of EGCG with ordered and disordered proteins
2018
·
Giuliana Fusco
, Maximo Sanz‐Hernandez
, et al.
·
Biopolymers
·
43
Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters
2018
·
Maria Romano
, Giuliana Fusco
, et al.
·
ACS Chemical Biology
·
40
PDF
Modeling Parkinson’s Disease Neuropathology and Symptoms by Intranigral Inoculation of Preformed Human α-Synuclein Oligomers
2020
·
Laura Boi
, Augusta Pisanu
, et al.
·
International Journal of Molecular Sciences
·
36
PDF
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease
2021
·
Michele Perni
, Annemieke van der Goot
, et al.
·
Frontiers in Cell and Developmental Biology
·
30
PDF
Local Ionic Conditions Modulate the Aggregation Propensity and Influence the Structural Polymorphism of α-Synuclein
2025
·
Maria Zacharopoulou
, Neeleema Seetaloo
, et al.
·
Journal of the American Chemical Society
·
19
Repurposing Pomalidomide as a Neuroprotective Drug: Efficacy in an Alpha-Synuclein-Based Model of Parkinson's Disease
2022
·
Maria Francesca Palmas
, Anna Ena
, et al.
·
Neurotherapeutics
·
19
PDF
1H, 13C and 15N resonance assignments of human muscle acylphosphatase
2011
·
Giuliana Fusco
, Alfonso De Simone
, et al.
·
Biomolecular NMR Assignments
·
16
Metal interactions of α-synuclein probed by NMR amide-proton exchange
2023
·
Mario Gonzalez-Garcia
, Giuliana Fusco
, et al.
·
Frontiers in Chemistry
·
15
α-Synuclein and biological membranes: the danger of loving too much
2023
·
Silvia Mansueto
, Giuliana Fusco
, et al.
·
Chemical Communications
·
15
PDF
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Works count:
54
Citation count:
3,075
H-index:
20
I10-index:
33
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