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Michael D. Bright

Observed names: Bright, Michael, Bright, Michael D., M D Bright, M. Bright, Michael Bright
ORCID: 0000-0003-2107-8491
Observed ORCID: 0000-0003-2107-8491
OpenAlex ID: A5050878713
Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements
2011 · Alexander R. C. Wong, Jaclyn S. Pearson, et al. · Molecular Microbiology · 377
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Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control
2017 · C Pawlyn, M D Bright, et al. · Blood Cancer Journal · 109
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Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders
2020 · Benjamin R. Bellenie, Kwai-Ming J. Cheung, et al. · Journal of Medicinal Chemistry · 72
Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress
2015 · Michael D. Bright, Daniel N. Itzhak, et al. · Molecular and Cellular Biology · 71
HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target
2018 · Jacqueline H.L. Fok, Somaieh Hedayat, et al. · Clinical Cancer Research · 55
The motor protein myosin 1G functions in FcγR-mediated phagocytosis
2012 · Anna E. Dart, Sylvain Tollis, et al. · Journal of Cell Science · 46
PAK1 and PAK2 have different roles in HGF-induced morphological responses
2009 · Michael D. Bright, Andrew P. Garner, et al. · Cellular Signalling · 37
An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration
2018 · Virginia Tajadura-Ortega, Ritu Garg, et al. · BMC Biology · 36
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Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors
2022 · Owen A. Davis, Kwai-Ming J. Cheung, et al. · Journal of Medicinal Chemistry · 25
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Oncogenic RAC1 and NRAS drive resistance to endoplasmic reticulum stress through MEK/ERK signalling
2018 · Michael D. Bright, Paul A. Clarke, et al. · Cellular Signalling · 25
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Multiple autophosphorylations significantly enhance the endoribonuclease activity of human inositol requiring enzyme 1α
2014 · Daniel Itzhak, Michael Bright, et al. · BMC Biochemistry · 20
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Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket
2021 · Matthew G. Lloyd, Rosemary Huckvale, et al. · Journal of Medicinal Chemistry · 16
Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo
2022 · Rosemary Huckvale, Alice C. Harnden, et al. · Journal of Medicinal Chemistry · 15
PAK4 phosphorylates myosin regulatory light chain and contributes to Fcγ receptor-mediated phagocytosis
2011 · Michael D. Bright, Gad Frankel · The International Journal of Biochemistry & Cell Biology · 13
Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones
2023 · Alice C. Harnden, Owen A. Davis, et al. · Journal of Medicinal Chemistry · 12
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Inhibition of the Epigenetic Modifier EZH2 Upregulates Cell Cycle Control Genes to Inhibit Myeloma Cell Growth and Overcome High-Risk Disease Features
2016 · Charlotte Pawlyn, Michael Bright, et al. · Blood · 2
Histone Demethylase Inhibition As a Novel Therapeutic Strategy in Myeloma
2014 · Charlotte Pawlyn, Edward Hookway, et al. · Blood · 1
CCDC 2163947: Experimental Crystal Structure Determination
2022 · Huckvale, Rosemary, Harnden, Alice C., et al. · The Cambridge Structural Database
Improved binding affinity and pharmacokinetics enables sustained degradation of BCL6 in vivo
2022 · A. Harnden, R. Huckvale, et al. · European Journal of Cancer
Additional file 1: of An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration
2018 · Tajadura-Ortega, Virginia, Garg, Ritu, et al. · Figshare
Abstract 469: Regulated IRE1-dependent mRNA decay occurs under extreme proteotoxic stress in myeloma, but not under conditions that would affect therapeutic targeting of IRE1α
2014 · Michael D. Bright, Christopher P. Wardell, et al. · Cancer Research
The role and regulation of PAK isoforms in cancer cell migration
2008 · Michael D. Bright · OpenGrey (Institut de l'Information Scientifique et Technique)
Works count: 22
Citation count: 931
H-index: 13
I10-index: 15
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