Author

Fabio Bonelli

Observed names: F Bonelli, F. Bonelli, FABIO BONELLI

Institution: IRBM

Observed institutions: Merck & Co., Inc., Rahway, NJ, USA (United States), MSD (Italy), Menarini Group (Italy), Institute of Molecular Biology and Pathology, LivaNova (Italy), IRBM

OpenAlex ID: A5053288890

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

2008 · Vincenzo Summa, Alessia Petrocchi, et al. · Journal of Medicinal Chemistry · 653

Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency

2009 · Paolo Ingallinella, Elisabetta Bianchi, et al. · Proceedings of the National Academy of Sciences · 220

A novel strategy for reducing phospholipids-based matrix effect in LC–ESI-MS bioanalysis by means of HybridSPE

2009 · Vincenzo Pucci, Serena Di Palma, et al. · Journal of Pharmaceutical and Biomedical Analysis · 149

Potent Inhibitors of Subgenomic Hepatitis C Virus RNA Replication through Optimization of Indole-N-Acetamide Allosteric Inhibitors of the Viral NS5B Polymerase

2005 · Steven Harper, Salvatore Avolio, et al. · Journal of Medicinal Chemistry · 86

Characterization of the Hepatitis C Virus NS2/3 Processing Reaction by Using a Purified Precursor Protein

2001 · Michele Pallaoro, Armin Lahm, et al. · Journal of Virology · 82

A novel, inducible, eukaryotic gene expression system based on the quorum‐sensing transcription factor TraR

2003 · Petra Neddermann, Cesare Gargioli, et al. · EMBO Reports · 81

Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors

2007 · Paola Pace, M. Emilia Di Francesco, et al. · Journal of Medicinal Chemistry · 80

Discovery and Synthesis of HIV Integrase Inhibitors: Development of Potent and Orally Bioavailable N-Methyl Pyrimidones

2007 · Cristina Gardelli, Emanuela Nizi, et al. · Journal of Medicinal Chemistry · 67

DPP‐IV‐resistant, long‐acting oxyntomodulin derivatives

2011 · Alessia Santoprete, Elena Capitò, et al. · Journal of Peptide Science · 64

Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor.

2005 · Fumi Kinose, Giuseppe Roscilli, et al. · PubMed · 42

Moving from fast to ballistic gradient in liquid chromatography/tandem mass spectrometry pharmaceutical bioanalysis: matrix effect and chromatographic evaluations

2006 · Claudio De Nardi, Fabio Bonelli · Rapid Communications in Mass Spectrometry · 39

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A multiple antigen peptide from the repetitive sequence of the Plasmodium malariae circumsporozoite protein induces a specific antibody response in mice of various H‐2 haplotypes

1990 · Giuseppe Del Giudice, Chantal Tougne, et al. · European Journal of Immunology · 32

Optimization of Thienopyrrole‐Based Finger‐Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase

2009 · Jose Ignacio Martin Hernando, Jesus Maria Ontoria, et al. · ChemMedChem · 31

Quantitative Prediction of Human Clearance Guiding the Development of Raltegravir (MK-0518, Isentress) and Related HIV Integrase Inhibitors

2009 · Ralph Laufer, Odalys Gonzalez Paz, et al. · Drug Metabolism and Disposition · 31

ApoA-I mimetic peptides promote pre-β HDL formation in vivo causing remodeling of HDL and triglyceride accumulation at higher dose

2010 · Ester Carballo-Jane, Zhu Chen, et al. · Bioorganic & Medicinal Chemistry · 30

HILIC LC‐MS for the determination of 2′‐C‐methyl‐cytidine‐triphosphate in rat liver

2009 · Vincenzo Pucci, Claudio Giuliano, et al. · Journal of Separation Science · 30

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Application of the continuous-flow polyamide method to the solid-phase synthesis of a multiple antigen peptide (MAP) based on the sequence of a malaria epitope

1990 · Antonello Pessi, Elisabetta Bianchi, et al. · Journal of the Chemical Society Chemical Communications · 28

Oligomerization, albumin binding and catabolism of therapeutic peptides in the subcutaneous compartment: An investigation on lipidated GLP-1 analogs

2022 · Mariana Gallo, Domitilla Vanni, et al. · Journal of Pharmaceutical and Biomedical Analysis · 26

An efficient liquid chromatography-high resolution mass spectrometry approach for the optimization of the metabolic stability of therapeutic peptides

2017 · Simone Esposito, Riccardo Mele, et al. · Analytical and Bioanalytical Chemistry · 25

Preclinical pharmacokinetics and metabolism of a potent non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase

2005 · C. Giuliano, F. Fiore, et al. · Xenobiotica · 22

Epitope mapping of the NS4 and NS5 gene products of hepatitis C virus and the use of a chimeric NS4-NS5 synthetic peptide for serodiagnosis

1995 · C. Rosa, S. Osborne, et al. · Journal of Virological Methods · 22

Turbulent Flow Chromatography TFC-tandem mass spectrometry supporting in vitro/vivo studies of NCEs in high throughput fashion

2009 · Maria Verdirame, Maria Veneziano, et al. · Journal of Pharmaceutical and Biomedical Analysis · 21

High sensitivity determination of valproic acid in mouse plasma using semi‐automated sample preparation and liquid chromatography with tandem mass spectrometric detection

2005 · Vincenzo Pucci, Edith Monteagudo, et al. · Rapid Communications in Mass Spectrometry · 20

Use of ‘dilute-and-shoot’ liquid chromatography-high resolution mass spectrometry in preclinical research: application to a DMPK study of perhexiline in mouse plasma

2015 · Simone Esposito, Elena Bracacel, et al. · Journal of Pharmaceutical and Biomedical Analysis · 19

Determination of acetyl coenzyme A in human whole blood by ultra-performance liquid chromatography-mass spectrometry

2018 · Roberto Speziale, Camilla Montesano, et al. · Journal of Chromatography B · 17

Works count: 48

Citation count: 2,069

H-index: 21

I10-index: 32