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Manikkam Rajalakshmi

Observed names: M. Rajalakshmi, MANIKKAM RAJALAKSHMI, RAJALAKSHMI M., Rajalakshmi Manikkam, Rajalakshmi, Manikkam
ORCID: 0000-0003-0713-6974
Observed ORCID: 0000-0003-0713-6974
OpenAlex ID: A5054003075
Insulin mimetic impact of Catechin isolated from Cassia fistula on the glucose oxidation and molecular mechanisms of glucose uptake on Streptozotocin-induced diabetic Wistar rats
2009 · P. Daisy, K. Balasubramanian, et al. · Phytomedicine · 136
Cytotoxic Impact of Costunolide Isolated fromCostus speciosuson Breast Cancer via Differential Regulation of Cell Cycle-AnIn-vitroandIn-silico Approach
2015 · Anita Roy, Rajalakshmi Manikkam · Phytotherapy Research · 42
Octyl gallate and gallic acid isolated from Terminalia bellarica regulates normal cell cycle in human breast cancer cell lines
2018 · Mary Selesty Sales, Anita Roy, et al. · Biomedicine & Pharmacotherapy · 40
β-cell regenerative efficacy of a polysaccharide isolated from methanolic extract of Tinospora cordifolia stem on streptozotocin -induced diabetic Wistar rats
2015 · Manikkam Rajalakshmi, Roy Anita · Chemico-Biological Interactions · 39
Database on pharmacophore analysis of active principles, from medicinal plants
2010 · Daisy Pitchai, Rajalakshmi Manikkam, et al. · Bioinformation · 33
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Inhibition of cell survival and proliferation by nimbolide in human androgen-independent prostate cancer (PC-3) cells: involvement of the PI3K/Akt pathway
2016 · Paulraj Raja Singh, Elayapillai Sugantha Priya, et al. · Molecular and Cellular Biochemistry · 31
Computational, antimicrobial, DNA binding and anticancer activities of pyrimidine incorporated ligand and its copper(II) and zinc(II) complexes
2018 · Murugesan Sankarganesh, Nagaraj Revathi, et al. · Journal of the Serbian Chemical Society · 29
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Virtual screening of potential inhibitor against FtsZ protein from Staphylococcus aureus
2014 · Periyasamy Vijayalakshmi, Jaganathan Nisha, et al. · Interdisciplinary Sciences Computational Life Sciences · 28
Hypoglycemic and insulin mimetic impact of catechin isolated from Cassia fistula: a substantiate in silico approach through docking analysis
2011 · Daisy Pitchai, Rajalakshmi Manikkam · Medicinal Chemistry Research · 27
A database for the predicted pharmacophoric features of medicinal compounds
2011 · Pitchai Daisy, Sanjeev Kumar Singh, et al. · Bioinformation · 25
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Metabolism-dependent cytotoxicity of citrinin and ochratoxin A alone and in combination as assessed adopting integrated discrete multiple organ co-culture (IdMOC)
2017 · Loganathan Gayathri, Bagavathy Shanmugam Karthikeyan, et al. · Toxicology in Vitro · 20
Novel Triterpenoids from Cassia fistula Stem Bark Depreciates STZ-Induced Detrimental Changes in IRS-1/Akt-Mediated Insulin Signaling Mechanisms in Type-1 Diabetic Rats
2021 · Sabapathy Indu, Periyasamy Vijayalakshmi, et al. · Molecules · 15
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Hypolipidemic, hepato-protective and renal damage recovering effects of catechin isolated from the methanolic extract of Cassia fistula stem bark on Streptozotocin-induced diabetic Wistar rats: a biochemical and morphological analysis
2012 · Daisy Pitchai, Rajalakshmi Manikkam · Medicinal Chemistry Research · 13
Normalizing effects of Costus speciosus rhizome crude extracts and its fractions on diabetic complications in STZ-induced diabetic rats
2010 · J. Eliza, M. Rajalakshmi, et al. · Medicinal Chemistry Research · 13
Effects of dihydroxy gymnemic triacetate (DGT) on expression of apoptosis associated proteins in human prostate cancer cell lines (PC3)
2015 · Rajamanickam Pon Nivedha, Jayaraman Selvaraj, et al. · Journal of Receptors and Signal Transduction · 10
Octyl Gallate and Gallic Acid Isolated from Terminalia bellirica Circumvent Breast Cancer Progression by Enhancing the Intrinsic Apoptotic Signaling Pathway and Elevating the Levels of Anti-oxidant Enzymes
2023 · Periyasamy Vijayalakshmi, Sabapathy Indu, et al. · Applied Biochemistry and Biotechnology · 9
Triterpenoids from Cassia fistula L. regulate p53 & ERK2 genes to induce apoptosis in HT-29 colon cancer cells
2019 · Rajini M. Kumar, Jeyapriyadharshini S, et al. · Biocatalysis and Agricultural Biotechnology · 7
Chemopreventive effect of saponin isolated from Gymnema sylevestre on prostate cancer through in silico and in vivo analysis
2017 · Rajamanickam Pon Nivedha, Venkatesan Suryanarayanan, et al. · Medicinal Chemistry Research · 6
Molecular docking analysis of quercetin with known CoVid-19 targets
2023 · Rajalakshmi Manikkam · Bioinformation · 5
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DaiCee: A database for anti-cancer compounds with targets and side effect profiles
2020 · Manikkam Rajalakshmi, Sugumaran Suveena, et al. · Bioinformation · 5
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Anti-cancer Potential of Polysaccharide Isolated From Methanolic Extract of Tinospora Cordifolia Stem Bark
2019 · ANTONY LUDAS, SABAPATHY INDU, et al. · International Journal of Pharmacy and Pharmaceutical Sciences · 5
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Synergistic Effects of Multifunctional Phytochemicals Modulating the Cellular Signal Pathways – as Neuroprotective Therapeutic Approach for Neurodegenerative Disorders
2024 · Rajalakshmi Manikkam, Indu Sabapathy, et al. · Springer eBooks · 3
Phytochemical screening and anti-obesity, anti- diabetic and anti-oxidant properties of Scoparia dulcis leaf decoction (crude)
2023 · Arulandhu Clara Mary, Christopher Ireen, et al. · Bioinformation · 3
Repurposing of phytocompounds-derived novel bioactive compounds possessing promising anticancer and cancer therapeutic efficacy through molecular docking, MD simulation, and drug-likeness/ADMET studies
2023 · Rajalakshmi Manikkam, Vijayalakshmi Periyasamy, et al. · Elsevier eBooks · 3
Antioxidant Potential of Polysaccharide Isolated From Methanolic Extract of Tinospora Cordifolia Stem Bark
2018 · Antony Ludas, Sabapathy Indu, et al. · Asian Journal of Pharmaceutical and Clinical Research · 3
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Works count: 52
Citation count: 566
H-index: 13
I10-index: 15
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