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Mohamed Elagawany

Expanding the anticancer potential of 1,2,3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases
2020 · Perihan A. Elzahhar, Shrouk M. Abd El Wahab, et al. · European Journal of Medicinal Chemistry · 89
4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments
2023 · Mahmoud A. Ragab, Wagdy M. Eldehna, et al. · European Journal of Medicinal Chemistry · 60
Design, synthesis and biological evaluation of novel 5-((substituted quinolin-3-yl/1-naphthyl) methylene)-3-substituted imidazolidin-2,4-dione as HIV-1 fusion inhibitors
2020 · Tarek S. Ibrahim, Riham M. Bokhtia, et al. · Bioorganic Chemistry · 47
Ligand-based design, synthesis, computational insights, and in vitro studies of novel N -(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease
2022 · Mohamed Elagawany, Ayman Abo Elmaaty, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 43
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Macrocyclic peptidomimetics with antimicrobial activity: synthesis, bioassay, and molecular modeling studies
2015 · Mohamed A. Ibrahim, Siva S. Panda, et al. · Organic & Biomolecular Chemistry · 41
Design, synthesis, and molecular modelling of pyridazinone and phthalazinone derivatives as protein kinases inhibitors
2013 · Mohamed Elagawany, Mohamed A. Ibrahim, et al. · Bioorganic & Medicinal Chemistry Letters · 35
Synthesis and Evaluation of Troponoids as a New Class of Antibiotics
2018 · Feng Cao, Cari Orth, et al. · ACS Omega · 33
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Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy
2020 · Tarek S. Ibrahim, Mohamed M. Hawwas, et al. · Bioorganic Chemistry · 27
Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights
2023 · Waleed A. Badawi, Mahmoud Rashed, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 26
Synthesis, computational studies, antimycobacterial and antibacterial properties of pyrazinoic acid–isoniazid hybrid conjugates
2019 · Siva S. Panda, Adel S. Girgis, et al. · RSC Advances · 24
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Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffold
2018 · Shaimaa S. Goher, Kristine Griffett, et al. · Bioorganic & Medicinal Chemistry Letters · 24
Modulation of estrogen-related receptors subtype selectivity: Conversion of an ERRβ/γ selective agonist to ERRα/β/γ pan agonists
2020 · Mohamed Shahien, Mohamed Elagawany, et al. · Bioorganic Chemistry · 21
Biological evaluation and molecular docking study of metabolites from Salvadora Persica L. Growing in Egypt
2019 · AhmedM Metwaly, MohammedM Ghoneim, et al. · Pharmacognosy Magazine · 21
Traceless chemical ligations from O-acyl serine sites
2012 · Mirna El Khatib, Mohamed Elagawany, et al. · Organic & Biomolecular Chemistry · 20
Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N -(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies
2023 · Ahmed A. Al-Karmalawy, Dalia S. El-Gamil, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 19
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Identification of 4-isopropyl–thiotropolone as a novel anti-microbial: regioselective synthesis, NMR characterization, and biological evaluation
2018 · Mohamed Elagawany, Lamees Hegazy, et al. · RSC Advances · 17
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Total synthesis of cyclic heptapeptide Rolloamide B
2013 · Mirna El Khatib, Mohamed Elagawany, et al. · Chemical Communications · 17
Discovery of Novel Piperidinyl-Based Benzoxazole Derivatives as Anticancer Agents Targeting VEGFR-2 and c-Met Kinases
2025 · Wagdy M. Eldehna, Zainab M. Elsayed, et al. · Pharmaceuticals · 15
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Towards the Development of Dual Hypouricemic and Anti-inflammatory Candidates: Design, Synthesis, Stability Studies and Biological Evaluation of Some Mutual Ester Prodrugs of Febuxostat-NSAIDs
2023 · Aya Y. Rashad, Hoda G. Daabees, et al. · Bioorganic Chemistry · 15
Development of certain benzylidene coumarin derivatives as anti-prostate cancer agents targeting EGFR and PI3Kβ kinases
2024 · Lina M. A. Abdel Ghany, Tarek S. Ibrahim, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 13
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A New Avenue for Enhanced Treatment of Hyperuricemia and Oxidative Stress: Design, Synthesis and Biological Evaluation of Some Novel Mutual Prodrugs Involving Febuxostat Conjugated with Different Antioxidants
2023 · Aya Y. Rashad, Hoda G. Daabees, et al. · Bioorganic Chemistry · 13
Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity
2021 · Mahmoud A. Ragab, Mohamed Elagawany, et al. · Bioorganic Chemistry · 13
Catalyst- and organic solvent-free synthesis of thioacids in water
2019 · Mohamed Elagawany, Lamees Hegazy, et al. · Tetrahedron Letters · 13
One-pot synthesis of bi- and tricyclic heterocyclic compounds using benzotriazole chemistry
2016 · Mohamed Elagawany, Mohamed A. Ibrahim, et al. · Tetrahedron Letters · 13
Identification of Novel Triazole–Pyrazole Conjugates as Potential Anticonvulsant Agents: Synthesis and Biological Evaluations
2025 · Wagdy M. Eldehna, Mahmoud Abdelrahman Alkabbani, et al. · ACS Chemical Neuroscience · 11
Works count: 72
Citation count: 827
H-index: 17
I10-index: 28
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