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Dominique Guianvarc’h

Observed names: D. Guianvarch, D. Guianvarc’h, Dominique Guianvarc'h, Guianvarc', Dominique, Guianvarc'h, Dominique, Guianvarc’h, Dominique
Observed institutions: Université Paris-Sud, Mohammed V University, Centre National de la Recherche Scientifique, Institut de Chimie des Substances Naturelles, Inserm, Université Paris Sciences et Lettres, Université Paris-Saclay, École Normale Supérieure - PSL, Sorbonne Université, Institut de Chimie de Nice, Muséum national d'Histoire naturelle, Servier (France), Laboratoire de Chimie Organique, Institut de Chimie Moléculaire et des Matériaux d'Orsay, Laboratoire des Biomolécules, Structure et Instabilité des Génomes, Université Nice Sophia Antipolis, Université Pierre-et-Marie-Curie, Institut de Recherches Internationales Servier (France), Institut Curie
ORCID: 0000-0002-7722-370X
Observed ORCID: 0000-0002-7722-370X
OpenAlex ID: A5055175336
Mechanistic Insights on the Inhibition of C5 DNA Methyltransferases by Zebularine
2010 · Christine Champion, Dominique Guianvarc'h, et al. · PLoS ONE · 118
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Synthesis and Evaluation of Analogues of N -Phthaloyl- l -tryptophan (RG108) as Inhibitors of DNA Methyltransferase 1
2013 · Saâdia Asgatay, Christine Champion, et al. · Journal of Medicinal Chemistry · 111
Biotin Synthase, a New Member of the Family of Enzymes Which Uses S-Adenosylmethionine as a Source of Deoxyadenosyl Radical
1997 · Dominique Guianvarc'h, Dominique Florentin, et al. · Biochemical and Biophysical Research Communications · 110
C5‐DNA Methyltransferase Inhibitors: From Screening to Effects on Zebrafish Embryo Development
2011 · Alexandre Ceccaldi, Arumugam Rajavelu, et al. · ChemBioChem · 101
Rapid Synthesis of New DNMT Inhibitors Derivatives of Procainamide
2011 · Ludovic Halby, Christine Champion, et al. · ChemBioChem · 72
Incorporation of a novel nucleobase allows stable oligonucleotide-directed triple helix formation at the target sequence containing a purine·pyrimidine interruption
2001 · Dominique Guianvarc’h, Rachid Benhida, et al. · Chemical Communications · 72
Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells
2017 · Ludovic Halby, Yoann Menon, et al. · Journal of Medicinal Chemistry · 70
Identification of Novel Inhibitors of DNA Methylation by Screening of a Chemical Library
2013 · Alexandre Ceccaldi, Arumugam Rajavelu, et al. · ACS Chemical Biology · 65
Combined analysis of DNA methylation and cell cycle in cancer cells
2015 · Cécile Desjobert, Mounir El Maï, et al. · Epigenetics · 58
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Evaluation of borinic acids as new, fast hydrogen peroxide–responsive triggers
2021 · Blaise Gatin-Fraudet, Roxane Ottenwelter, et al. · Proceedings of the National Academy of Sciences · 57
Stereocontrolled Synthesis of Heterocyclic C-Nucleosides. Protecting Group Effect and Molecular Modeling Studies
2002 · Dominique Guianvarc'h, Jean-Louis Fourrey, et al. · The Journal of Organic Chemistry · 55
Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors
2018 · Ludovic Halby, Nils Marechal, et al. · Philosophical Transactions of the Royal Society B Biological Sciences · 47
Design of artificial nucleobases for the recognition of the AT inversion by triple-helix forming oligonucleotides: A structure–stability relationship study and neighbour bases effect
2003 · Dominique Guianvarc'h, Jean-Louis Fourrey, et al. · Bioorganic & Medicinal Chemistry · 47
Synthesis, Incorporation into Triplex-Forming Oligonucleotide, and Binding Properties of a Novel 2‘-Deoxy-C-Nucleoside Featuring a 6-(Thiazolyl-5)benzimidazole Nucleobase
2002 · Dominique Guianvarc'h, Jean-Louis Fourrey, et al. · Organic Letters · 45
Synthesis and Biological Activity of Sulfonamide Derivatives of Epipodophyllotoxin
2004 · Dominique Guianvarc'h, Maria Duca, et al. · Journal of Medicinal Chemistry · 42
Synthesis and Biological Study of a New Series of 4‘-Demethylepipodophyllotoxin Derivatives
2004 · Maria Duca, Dominique Guianvarc'h, et al. · Journal of Medicinal Chemistry · 39
Exploring the Cellular Activity of Camptothecin-Triple-Helix-Forming Oligonucleotide Conjugates
2005 · Paola B. Arimondo, Craig J. Thomas, et al. · Molecular and Cellular Biology · 30
Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides
2006 · M. Duca, Dominique Guianvarc'h, et al. · Nucleic Acids Research · 27
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Identification of new inhibitors of E. coli cyclopropane fatty acid synthase using a colorimetric assay
2006 · Dominique Guianvarc'h, Thierry Drujon, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 26
Efficient stereocontrolled synthesis of 2-benzimidazolyl- and 2-indolyl-C-nucleosides
2001 · Dominique Guianvarc'h, Rachid Benhida, et al. · Tetrahedron Letters · 25
A direct label-free MALDI-TOF mass spectrometry based assay for the characterization of inhibitors of protein lysine methyltransferases
2017 · Karine Guitot, Thierry Drujon, et al. · Analytical and Bioanalytical Chemistry · 22
Label-free measurement of histone lysine methyltransferases activity by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
2014 · Karine Guitot, Silvia Scarabelli, et al. · Analytical Biochemistry · 22
A short and efficient synthesis of 2′-deoxybenzo- and pyridoimidazole C-nucleosides
2003 · Mohamed Jazouli, Dominique Guianvarc'h, et al. · Tetrahedron Letters · 22
A short and highly stereoselective synthesis of α-(2-aminothiazolyl)-C-nucleosides
2003 · Jean-Michel Navarre, Dominique Guianvarc'h, et al. · Tetrahedron Letters · 21
First access to a mycolic acid-based bioorthogonal reporter for the study of the mycomembrane and mycoloyltransferases in Corynebacteria
2019 · Emilie Lesur, Aurélie Baron, et al. · Chemical Communications · 20
Works count: 95
Citation count: 1,567
H-index: 22
I10-index: 37
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