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Leontien Bosch

CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells
2010 · Sven Jähnichen, Christophe Blanchetot, et al. · Proceedings of the National Academy of Sciences · 265
Focal aberrations indicate EYA2 and hsa‐miR‐375 as oncogene and tumor suppressor in cervical carcinogenesis
2012 · Mariska Bierkens, Oscar Krijgsman, et al. · Genes Chromosomes and Cancer · 89
Retracted: Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity
2023 · Claire Vennin, Chiara M. Cattaneo, et al. · Cancer Cell · 66
Noncompetitive Antagonism and Inverse Agonism as Mechanism of Action of Nonpeptidergic Antagonists at Primate and Rodent CXCR3 Chemokine Receptors
2008 · Dennis Verzijl, Stefania Storelli, et al. · Journal of Pharmacology and Experimental Therapeutics · 62
Gene replacement ameliorates deficits in mouse and human models of cyclin-dependent kinase-like 5 disorder
2020 · Yunan Gao, Elaine E Irvine, et al. · Brain · 59
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Neutralizing Nanobodies Targeting Diverse Chemokines Effectively Inhibit Chemokine Function
2013 · Christophe Blanchetot, Dennis Verzijl, et al. · Journal of Biological Chemistry · 55
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Methylation-mediated repression of PRDM14 contributes to apoptosis evasion in HPV-positive cancers
2014 · S. Snellenberg, S. A. G. M. Cillessen, et al. · Carcinogenesis · 47
Nonpeptidergic Allosteric Antagonists Differentially Bind to the CXCR2 Chemokine Receptor
2009 · Petra de Kruijf, Jane van Heteren, et al. · Journal of Pharmacology and Experimental Therapeutics · 43
Differential In Vitro Immortalization Capacity of Eleven, Probable High-Risk Human Papillomavirus Types
2013 · Denise M. Schütze, Peter J. F. Snijders, et al. · Journal of Virology · 34
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Immortalization capacity of HPV types is inversely related to chromosomal instability
2016 · Denise M. Schütze, Oscar Krijgsman, et al. · Oncotarget · 31
Development of a replication‐deficient adenoviral vector‐based vaccine candidate for the interception of HPV16‐ and HPV18‐induced infections and disease
2017 · Selina Khan, Koen Oosterhuis, et al. · International Journal of Cancer · 29
Synthesis and Structure‐Activity Relationships of 3H‐Quinazolin‐4‐ones and 3H‐Pyrido[2,3‐d]pyrimidin‐4‐ones as CXCR3 receptor antagonists
2007 · Stefania Storelli, Dennis Verzijl, et al. · Archiv der Pharmazie · 24
CXCR3 antagonists: Quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors
2011 · Maikel Wijtmans, Dennis Verzijl, et al. · Bioorganic & Medicinal Chemistry · 23
Ultrarapid Delayed Rectifier K+ Channelopathies in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
2020 · Sarah Hilderink, Harsha D. Devalla, et al. · Frontiers in Cell and Developmental Biology · 20
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The functional role of Notch signaling in HPV-mediated transformation is dose-dependent and linked to AP-1 alterations
2012 · Florianne E. Henken, Johanna De-Castro Arce, et al. · Cellular Oncology · 20
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Luminescence-based screening for extracellular vesicle release modulators reveals a role for PI4KIIIβ in exosome biogenesis upon lysosome inhibition
2023 · Maarten P. Bebelman, Caitrin Crudden, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 16
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Tumor-Secreted Extracellular Vesicles Counteract Therapy Response by Triggering Inflammatory Mesenchymal Stem Cell Development
2024 · Crescenzo Massaro, Hilal N. Sensoy, et al. · Clinical Cancer Research · 15
Comparison of cell-free and small extracellular-vesicle-associated DNA by sequencing plasma of lung cancer patients
2024 · Norbert Moldovan, Sandra Verkuijlen, et al. · iScience · 13
Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7
2012 · F.E. Henken, K. Oosterhuis, et al. · Vaccine · 11
Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy
2009 · Maikel Wijtmans, Dennis Verzijl, et al. · Bioorganic & Medicinal Chemistry Letters · 9
Circulating extracellular vesicle isomiR signatures predict therapy response in patients with multiple myeloma
2025 · Cristina Gómez-Martín, Esther E.E. Drees, et al. · Cell Reports Medicine · 6
Unbiased and UMI-informed sequencing of cell-free miRNAs at single-nucleotide resolution
2021 · M.A.J. van Eijndhoven, E. Aparicio-Puerta, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5
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Full-length tRNAs lacking a functional CCA tail are selectively sorted into the lumen of extracellular vesicles
2024 · Chantal Scheepbouwer, Ernesto Aparicio-Puerta, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 3
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Small and Large Extracellular Vesicles in Circulation of Diffuse Large B‐Cell Lymphoma Patients Originate From Different Cell Types of the Tumor Microenvironment
2026 · Filippo Maltoni, Steven Wang, et al. · Journal of Extracellular Vesicles · 1
Synthesis and Structure—Activity Relationships of 3H‐Quinazolin‐4‐ones and 3H‐Pyrido[2,3‐d]pyrimidin‐4‐ones as CXCR3 Receptor Antagonists.
2007 · Stefania Storelli, Dennis Verzijl, et al. · ChemInform · 1
Works count: 39
Citation count: 947
H-index: 16
I10-index: 19
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