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Matilda J. Bingham

Recent progress in the design and synthesis of artificial enzymes
2001 · W.B. Motherwell, M.J. Bingham, et al. · Tetrahedron · 264
Ring‐Closing Metathesis as a Basis for the Construction of Aromatic Compounds
2006 · Timothy J. Donohoe, Allan J. Orr, et al. · Angewandte Chemie International Edition · 189
A Metathesis Approach to Aromatic Heterocycles
2005 · Timothy J. Donohoe, Allan J. Orr, et al. · European Journal of Organic Chemistry · 57
Flexible metathesis-based approaches to highly functionalised furans and pyrroles
2007 · Timothy J. Donohoe, Neil M. Kershaw, et al. · Tetrahedron · 55
A study of some molecularly imprinted polymers as protic catalysts for the isomerisation of α-pinene oxide to trans-carveol
2004 · William B. Motherwell, Matilda J. Bingham, et al. · Tetrahedron · 47
The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand–dependent Cancer Models
2022 · Caroline Phillips, Inder Bhamra, et al. · Cancer Research Communications · 40
Ringschlussmetathese: ein Schlüssel zur Arensynthese
2006 · Timothy J. Donohoe, Allan J. Orr, et al. · Angewandte Chemie · 38
Eating, sleeping and rewarding: orexin receptors and their antagonists.
2006 · Matilda J Bingham, Jiaqiang Cai, et al. · PubMed · 28
A Simple Route to Functionalized Δ1-Pyrrolenines
2013 · Samir Z. Zard, Matilda Bingham, et al. · Heterocycles · 20
Development of an organo- and enzyme-catalysed one-pot, sequential three-component reaction
2012 · Angela Kinnell, Thomas Harman, et al. · Tetrahedron · 17
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Transporters as Targets for Drugs
2009 · Susan Napier, Matilda Bingham · Topics in medicinal chemistry · 12
Medicinal Chemistry Challenges in CNS Drug Discovery
2012 · Matilda Bingham, Zoran Rankovic · Royal Society of Chemistry eBooks · 11
Novel porcupine (PORCN) inhibitor RXC004: Evaluation in models of RNF43 loss of function cancers.
2017 · Inder Bhamra, Nick Adams, et al. · Journal of Clinical Oncology · 10
Abstract 3764: Porcupine inhibitor RXC004 enhances immune response in pre-clinical models of cancer
2018 · Inder Bhamra, Richard Armer, et al. · Cancer Research · 9
The identification, and optimisation of hERG selectivity, of a mixed NET/SERT re-uptake inhibitor for the treatment of pain
2010 · Derek Angus, Matilda Bingham, et al. · Bioorganic & Medicinal Chemistry Letters · 9
The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists
2011 · Susan Napier, Grant Wishart, et al. · Bioorganic & Medicinal Chemistry Letters · 8
Biophysical screening and characterisation in medicinal chemistry
2023 · Matilda Bingham, Thomas Pesnot, et al. · Progress in medicinal chemistry · 5
Novel C-7 carbon substituted fourth generation fluoroquinolones targeting N. Gonorrhoeae infections
2020 · Ralph Kirk, Mark Betson, et al. · Bioorganic & Medicinal Chemistry Letters · 5
Abstract 5160: Development of REDX05358, a novel highly selective and potent pan RAF inhibitor and a potential therapeutic for BRAF and RAS mutant tumors
2017 · Helen Mason, Simon Scrace, et al. · Cancer Research · 4
REDX08608, a Novel, Potent and Selective, Reversible BTK Inhibitor with Efficacy and Equivalent Potency Against Wild-Type and Mutant C481S BTK
2016 · Nicolas E. S. Guisot, Stuart A. Best, et al. · Blood · 4
Optimisation of pharmacokinetic properties to afford an orally bioavailable and selective V1A receptor antagonist
2011 · William Arbuckle, James Baker, et al. · Bioorganic & Medicinal Chemistry Letters · 4
P016 GI restricted ROCK inhibitors show potential to treat fibrosis and stenosis associated with inflammatory bowel disease
2018 · C Jones, P Bunyard, et al. · Journal of Crohn s and Colitis · 2
Overview: Transporters as Targets for Drug Discovery
2009 · Matilda Bingham, Susan Napier · Topics in medicinal chemistry · 2
Identification of an RNF43 mutated gastric cancer patient population with potential sensitivity to porcupine inhibitor RXC004 and development of a complimentary ctDNA liquid biopsy assay for patient screening
2017 · M. Bingham, I. Bhamra, et al. · Annals of Oncology · 1
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Novel Porcupine inhibitor RXC004: Potent efficacy in animal models of cancer through direct tumour targeting and immunomodulatory mechanisms
2016 · I. Bhamra, V. Abet, et al. · European Journal of Cancer · 1
Works count: 78
Citation count: 845
H-index: 11
I10-index: 13
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