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Jan Jaap van Lier

Observed names: J J van Lier, J. J. Van Lier, J. J. van Lier, J. van Lier, J.J van Lier, J.J. Van Lier, J.J. van Lier, Jan J van Lier, Jan J. Van Lier, Jan J. van Lier, Jan Jaap Van Lier, Jan van Lier
ORCID: 0000-0001-9676-5136
Observed ORCID: 0000-0001-9676-5136
OpenAlex ID: A5055811263
Metabolism and Excretion of the Once-Daily Human Glucagon-Like Peptide-1 Analog Liraglutide in Healthy Male Subjects and Its In Vitro Degradation by Dipeptidyl Peptidase IV and Neutral Endopeptidase
2010 · Monika Malm-Erjefält, Inga Bjørnsdottir, et al. · Drug Metabolism and Disposition · 222
Absorption, metabolism and excretion of the GLP-1 analogue semaglutide in humans and nonclinical species
2017 · Lene Jensen, Hans Helleberg, et al. · European Journal of Pharmaceutical Sciences · 193
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Antiviral activity, pharmacokinetics and safety of vicriviroc, an oral CCR5 antagonist, during 14-day monotherapy in HIV-infected adults
2007 · Dirk Schürmann, Gerd Fätkenheuer, et al. · AIDS · 85
Absorption, metabolism and excretion of a single oral dose of 14 C-repaglinide during repaglinide multiple dosing
1999 · P. N. M. van Heiningen, V. Hatorp, et al. · European Journal of Clinical Pharmacology · 83
Oral ferroportin inhibitor VIT‐2763: First‐in‐human, phase 1 study in healthy volunteers
2019 · Frank Richard, Jan Jaap van Lier, et al. · American Journal of Hematology · 75
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Absorption, Metabolism and Excretion of [14C]Mirabegron (YM178), a Potent and Selective β3-Adrenoceptor Agonist, after Oral Administration to Healthy Male Volunteers
2012 · Shin Takusagawa, Jan Jaap van Lier, et al. · Drug Metabolism and Disposition · 65
Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite
2020 · Ulrike Glaenzel, Yi Jin, et al. · Drug Metabolism and Disposition · 62
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The cognitive, subjective, and physical effects of a ginkgo biloba/panax ginseng combination in healthy volunteers with neurasthenic complaints.
1997 · K A Wesnes, R A Faleni, et al. · PubMed · 60
The Effect of Telmisartan on the Steady‐State Pharmacokinetics of Digoxin in Healthy Male Volunteers
2000 · Joachim Stangier, Chung‐An P. F. Su, et al. · The Journal of Clinical Pharmacology · 54
Lack of Pharmacokinetic Interaction for ISIS 113715, a 2???-0-Methoxyethyl Modified Antisense Oligonucleotide Targeting Protein Tyrosine Phosphatase 1B Messenger RNA, with Oral Antidiabetic Compounds Metformin, Glipizide or Rosiglitazone
2006 · Richard S Geary, JoAnn D Bradley, et al. · Clinical Pharmacokinetics · 50
Inhibitory Effect of Telmisartan on the Blood Pressure Response to Angiotensin II Challenge
2001 · Joachim Stangier, Chung-An P. F. Su, et al. · Journal of Cardiovascular Pharmacology · 44
Absorption, metabolism and excretion of 14C-candesartan and 14C-candesartan cilexetil in healthy volunteers.
1997 · J J van Lier, P N van Heiningen, et al. · PubMed · 44
The absolute bioavailability and effect of food on the pharmacokinetics of zolmitriptan in healthy volunteers
1998 · Emma J. Seaber, Richard W. Peck, et al. · British Journal of Clinical Pharmacology · 43
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Antiviral Activity of Narlaprevir Combined with Ritonavir and Pegylated Interferon in Chronic Hepatitis C Patients
2010 · Joep de Bruijne, Jilling F. Bergmann, et al. · Hepatology · 40
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First‐in‐human study evaluating safety, pharmacokinetics, and pharmacodynamics of lorundrostat, a novel and highly selective aldosterone synthase inhibitor
2024 · Hidetoshi Shimizu, Michael A. Tortorici, et al. · Clinical and Translational Science · 34
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Absorption, distribution, metabolism and excretion of the P2Y12 receptor antagonist selatogrel after subcutaneous administration in healthy subjects
2019 · Mike Ufer, Christine Huynh, et al. · Xenobiotica · 29
Lack of effect of lacosamide on the pharmacokinetic and pharmacodynamic profiles of warfarin
2013 · Armel Stockis, Jan Jaap van Lier, et al. · Epilepsia · 26
Open-label, single-center, phase I trial to investigate the mass balance and absolute bioavailability of the highly selective oral MET inhibitor tepotinib in healthy volunteers
2020 · Andreas Johne, Holger Scheible, et al. · Investigational New Drugs · 25
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A pharmacokinetic study of radiprodil oral suspension in healthy adults comparing conventional venous blood sampling with two microsampling techniques
2019 · David Sciberras, Christian Otoul, et al. · Pharmacology Research & Perspectives · 24
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An evaluation of human ADME and mass balance studies using regular or low doses of radiocarbon
2016 · A.F. Roffel, S.P. van Marle, et al. · Journal of Labelled Compounds and Radiopharmaceuticals · 23
Metabolism and disposition of the αv‐integrin ß3/ß5 receptor antagonist cilengitide, a cyclic polypeptide, in humans
2015 · Andreas Becker, Oliver von Richter, et al. · The Journal of Clinical Pharmacology · 23
Absorption, Distribution, Metabolism, and Excretion of the Oral Prostaglandin D2 Receptor 2 Antagonist Fevipiprant (QAW039) in Healthy Volunteers and In Vitro
2017 · David Pearson, H. Markus Weiss, et al. · Drug Metabolism and Disposition · 22
Anticoagulant Pharmacodynamics of Tinzaparin Following 175 IU/kg Subcutaneous Administration to Healthy Volunteers
2001 · Jeffrey S. Barrett, James W. Hainer, et al. · Thrombosis Research · 22
Absorption, Distribution, Metabolism, and Excretion of [14C]iptacopan in Healthy Male Volunteers and in In Vivo and In Vitro Studies
2023 · Alexander David James, Kenneth Kulmatycki, et al. · Drug Metabolism and Disposition · 21
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Steady‐State Pharmacodynamics and Pharmacokinetics of Warfarin in the Presence and Absence of Telmisartan in Healthy Male Volunteers
2000 · Joachim Stangier, Chung‐An P. F. Su, et al. · The Journal of Clinical Pharmacology · 19
Works count: 46
Citation count: 1,511
H-index: 22
I10-index: 31
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