Author

Andrea Heger

Observed names: A Heger, A. Heger

Observed institution: Octapharma (Austria)

ORCID: 0000-0001-7722-6049

Observed ORCID: 0000-0001-7722-6049

OpenAlex ID: A5055812879

Biochemical quality of the pharmaceutically licensed plasma OctaplasLG® after implementation of a novel prion protein (PrPSc) removal technology and reduction of the solvent/detergent (S/D) process time

2009 · A. Heger, T.‐E. Svae, et al. · Vox Sanguinis · 61

Prion removal effect of a specific affinity ligand introduced into the manufacturing process of the pharmaceutical quality solvent/detergent (S/D)‐treated plasma OctaplasLG®

2009 · A. Neisser‐Svae, A. Bailey, et al. · Vox Sanguinis · 41

Five‐day stability of thawed plasma: solvent/detergent‐treated plasma comparable with fresh‐frozen plasma and plasma frozen within 24 hours

2015 · Andrea Neisser‐Svae, Laurenz Trawnicek, et al. · Transfusion · 34

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Stability of solvent/detergent-treated plasma and single-donor fresh-frozen plasma during 48h after thawing

2005 · Andrea Heger, Jürgen Römisch, et al. · Transfusion and Apheresis Science · 34

A biochemical comparison of a pharmaceutically licensed coagulation active plasma (Octaplas®) with a universally applicable development product (Uniplas) and single-donor FFPs subjected to methylene-blue dye and white-light treatment

2006 · Andrea Heger, Jürgen Römisch, et al. · Transfusion and Apheresis Science · 31

Separation of active and inactive forms of human antithrombin by heparin affinity chromatography

2002 · Andrea Heger, Tom Grunert, et al. · Thrombosis Research · 31

Normal levels of ADAMTS13 and factor H are present in the pharmaceutically licensed plasma for transfusion (Octaplas®) and in the universally applicable plasma (Uniplas) in development

2006 · A. Heger, C. Kannicht, et al. · Vox Sanguinis · 28

Frozen and freeze‐dried solvent/detergent treated plasma: Two different pharmaceutical formulations with comparable quality

2022 · Andrea Heger, Gerhard Gruber · Transfusion · 26

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Characterization of antithrombin III from human plasma by two‐dimensional gel electrophoresis and capillary electrophoretic methods

2003 · Leopold Kremser, Andrea Brückner, et al. · Electrophoresis · 25

Thrombin generation capacity is impaired in methylene-blue treated plasma compared to normal levels in single-donor fresh-frozen plasma, a licensed solvent/detergent-treated plasma (Octaplas®) and a development product (Uniplas®)

2007 · Katharina Pock, Andrea Heger, et al. · Transfusion and Apheresis Science · 24

Prion safety of transfusion plasma and plasma-derivatives typically used for prophylactic treatment

2008 · Tor-Einar Svae, Andrea Neisser-Svae, et al. · Transfusion and Apheresis Science · 17

Thirty years of experience with solvent/detergent‐treated plasma for transfusion medicine

2024 · Sabrina E. Racine‐Brzostek, Melissa M. Cushing, et al. · Transfusion · 15

Clotting factor activity in thawed Octaplas® LG during storage at 2–6°C for 6days from a quality assurance point of view

2012 · Mareike Kristina Keller, Martin Krebs, et al. · Transfusion and Apheresis Science · 13

Exact molecular mass determination of various forms of native and de‐N‐glycosylated human plasma‐derived antithrombin by means of electrospray ionization ion trap mass spectrometry

2004 · Martina Kleinova, Andrea Buchacher, et al. · Journal of Mass Spectrometry · 11

Thawing of Pooled, Solvent/Detergent-Treated Plasma octaplasLG®: Validation Studies Using Different Thawing Devices

2017 · Andrea Heger, Katharina Pock, et al. · Transfusion Medicine and Hemotherapy · 10

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Universal pooled plasma (Uniplas®) does not induce complement-mediated hemolysis of human red blood cells in vitro

2013 · Andrea Heger, Hubert Brandstätter, et al. · Transfusion and Apheresis Science · 10

Removal of prion infectivity by affinity ligand chromatography during OctaplasLG® manufacturing – results from animal bioassay studies

2011 · A. Heger, A. Bailey, et al. · Vox Sanguinis · 10

Comment on: Addendum to the British Committee for Standards in Haematology ( BCSH ): Guidelines for the use of fresh‐frozen plasma, cryoprecipitate and cryosupernatant, 2004 (Br. J Haematol 2004,126,11‐28)

2016 · Andrea Neisser‐Svae, Andrea Heger · British Journal of Haematology · 8

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Solvent/Detergent Plasma

2012 · Tor‐Einar Svae, Andrea Heger, et al. · Wiley eBooks · 8

Comparative biochemical studies of fresh frozen plasma and pooled solvent/detergent‐treated plasma (octaplas LG ®) with focus on protein S and its impact in different thrombin generation assay set‐ups

2016 · A. Heger, S. Janisch, et al. · Vox Sanguinis · 7

Thrombin generation potential and clot‐forming capacity of thawed fresh‐frozen plasma, plasma frozen within 24 h and solvent/detergent‐treated plasma (octaplas LG ®), during 5‐day storage at 1–6°C

2018 · A. Heger, A. Neisser‐Svae, et al. · Vox Sanguinis · 6

A biochemical quality study of a pharmaceutically licenced coagulation active plasma (Octaplas®) thawed by the SAHARA‐III dry tempering system compared to the regular use of a water bath

2007 · A. Heger, J. Römisch, et al. · Vox Sanguinis · 6

Quality differences between solvent/detergent plasmas and fresh‐frozen plasma

2007 · T.‐E. Svae, W. Frenzel, et al. · Transfusion Medicine · 5

Two solvent/detergent‐treated plasma products with a different biochemical profile

2016 · A. Neisser‐Svae, A. Heger · ISBT Science Series · 3

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Validation of current commercially‐available devices to thaw pooled, solvent/detergent‐treated human plasma

2024 · Andrea Heger, Michelle Gareis · Transfusion Medicine · 2

Works count: 31

Citation count: 466

H-index: 13

I10-index: 17