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Hannah J. Maple

Observed names: H.J. Maple, Hannah J Maple, Hannah Maple, Maple, Hannah J.
Observed institutions: Durham University, University of Bristol, Biomedical Translation Research Center, UCB Pharma (United Kingdom), R&D Systems (United States), MRC Integrative Epidemiology Unit
ORCID: 0000-0001-5050-0562
Observed ORCID: 0000-0001-5050-0562
OpenAlex ID: A5056208276
Developing degraders: principles and perspectives on design and chemical space
2019 · Hannah J. Maple, Nat Clayden, et al. · MedChemComm · 162
Automated Protein–Ligand Interaction Screening by Mass Spectrometry
2011 · Hannah J. Maple, Rachel A. Garlish, et al. · Journal of Medicinal Chemistry · 74
Diastereomeric Resolution Yields Highly Potent Inhibitor of SARS-CoV-2 Main Protease
2022 · Mark S. Cooper, Linlin Zhang, et al. · Journal of Medicinal Chemistry · 40
Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma
2021 · Darko Bosnakovski, Elizabeth T. Ener, et al. · Oncogenesis · 39
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Application of the Exactive Plus EMR for automated protein–ligand screening by non‐covalent mass spectrometry
2014 · Hannah J. Maple, Olaf Scheibner, et al. · Rapid Communications in Mass Spectrometry · 29
Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screening
2025 · Andreas Holmqvist, Nur Mehpare Kocaturk, et al. · Nature Communications · 27
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The Effect of Pre-Analytical Conditions on Blood Metabolomics in Epidemiological Studies
2019 · Diana L Santos Ferreira, Hannah J Maple, et al. · Metabolites · 25
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Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs
2025 · Marisa Actis, Joel Cresser-Brown, et al. · Journal of Medicinal Chemistry · 22
Development of an AchillesTAG degradation system and its application to control CAR-T activity
2021 · Gesine K. Veits, Christina S. Henderson, et al. · Current Research in Chemical Biology · 21
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Analysis of Streptomyces coelicolor Phosphopantetheinyl Transferase, AcpS, Reveals the Basis for Relaxed Substrate Specificity
2011 · Patrick Dall’Aglio, Christopher J. Arthur, et al. · Biochemistry · 20
Chirality: a key parameter in chemical probes
2023 · Andrew McGown, Jordan Nafie, et al. · RSC Chemical Biology · 13
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Synthesis and Biological Investigation of (+)-JD1, an Organometallic BET Bromodomain Inhibitor
2019 · Storm Hassell-Hart, Andrew Runcie, et al. · Organometallics · 11
α4/α9 Integrins Coordinate Epithelial Cell Migration Through Local Suppression of MAP Kinase Signaling Pathways
2021 · Willow Hight-Warburton, Robert Felix, et al. · Frontiers in Cell and Developmental Biology · 10
Structure-Based Optimization of Pyridone α-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease
2025 · Ravi Kumar Akula, Haifa El Kilani, et al. · Journal of Medicinal Chemistry · 8
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Reviewing the toolbox for degrader development in oncology
2021 · Joel O. Cresser-Brown, Graham P. Marsh, et al. · Current Opinion in Pharmacology · 8
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Solution Structure and Conformational Dynamics of a Doublet Acyl Carrier Protein from Prodigiosin Biosynthesis
2021 · Thitapa Thongkawphueak, Ashley J. Winter, et al. · Biochemistry · 8
The aqueous N-phosphorylation and N-thiophosphorylation of aminonucleosides
2014 · Louis P. Conway, Richard J. Delley, et al. · RSC Advances · 7
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Development of p300-targeting degraders with enhanced selectivity and onset of degradation
2025 · Graham P. Marsh, Mark S. Cooper, et al. · RSC Medicinal Chemistry · 6
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BromoCatch: a self-labelling tag platform for protein analysis and live cell imaging
2025 · Maria Rodriguez-Rios, Conner Craigon, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5
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Scale-up and optimization of the synthesis of dual CBP/BRD4 inhibitor ISOX-DUAL
2022 · Anthony K. Edmonds, Catherine S. Oakes, et al. · Organic & Biomolecular Chemistry · 4
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Identification of Differential Protein Binding Affinities in an Atropisomeric Pharmaceutical Compound by Noncovalent Mass Spectrometry, Equilibrium Dialysis, and Nuclear Magnetic Resonance
2013 · Hannah J. Maple, Rachel A. Garlish, et al. · Analytical Chemistry · 4
BromoCatch: a self-labelling tag platform for protein modification and live cell imaging
2026 · Maria Rodriguez-Rios, Conner Craigon, et al. · Nature Communications · 2
Structure-Guided Design of ISOX-DUAL-Based Degraders Targeting BRD4 and CBP/EP300: A Case of Degrader Collapse
2025 · Anthony K. Edmonds, Dimitrios-Ilias Balourdas, et al. · Journal of Medicinal Chemistry · 2
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Efficient, multi-hundred-gram scale access to E3 ubiquitin ligase ligands for degrader development
2023 · Mark S. Cooper, Mark C. Norley, et al. · Organic & Biomolecular Chemistry · 2
Linker-rigidified VHL homodimerizers convert degraders into stabilizers of non-ubiquitinable ternary complexes
2025 · Charlotte Crowe, Alessandra Salerno, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Works count: 48
Citation count: 552
H-index: 11
I10-index: 13
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